http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. High-energy lower-extremity trauma (HELET) is common in modern warfare, often resulting in severe tissue damage, chronic pain, neurovascular injury and significant muscle loss, according to the new research presented today at the 2013 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). http://medicalxpress.com/news/2013-03-military-personnel-duty-severe-injury.html Other Tue, 19 Mar 2013 04:40:12 EST news282886803 A new study has found a link between the activity levels of elderly people who have just been released from the hospital and the risk that they will require readmission within 30 days. http://medicalxpress.com/news/2013-03-recovery-motion-post-discharge-linked-hospital.html Health Wed, 13 Mar 2013 10:11:05 EST news282388257 Muscle withering can occur as part of the progression of many diseases, including cancer and muscular dystrophy, as well as during the normal aging process. Cellular organelles known as mitochondria provide energy for muscle contraction, and their fragmentation within muscle cells can lead to muscle wasting. Now, a team of researchers led by Ravi Kambadur at the A*STAR Singapore Institute for Clinical Sciences has identified a key role for mitochondrial E3 ubiquitin protein ligase 1 (Mul1) in mitochondrial fragmentation. Such fragmentation occurs in response to stimuli that cause muscle loss. http://medicalxpress.com/news/2013-03-cell-metabolism-muscle-loss-mitochondrial.html Medical research Wed, 13 Mar 2013 08:00:01 EST news282379201 People tend to lose muscle mass as they age; researchers are investigating ways to delay or counteract age-related muscle loss. A study conducted by the Exercise Metabolism Research Group at McMaster University suggests that current guidelines for meat consumption are based on the protein needed to prevent deficiency without consideration for preservation of muscle mass, particularly for older individuals who are looking to maintain their muscle as they age. This research was published in the journal Applied Physiology, Nutrition, and Metabolism. http://medicalxpress.com/news/2013-02-beef-middle-aged-men-muscle-mass.html Health Mon, 04 Feb 2013 10:45:32 EST news279197115 Many cancer patients suffer from a dramatic loss of fat and muscle mass. This extreme wasting, or cachexia, is often the actual cause of death in cancer patients. Heidelberg scientists have now discovered in mice that tumors stimulate the production of a key gene switch in the liver. Activity of this switch lowers blood fat levels so that the animals lose weight. This finding may lead to approaches to slow down this fatal loss of body mass. http://medicalxpress.com/news/2013-01-liver-cancer-overactive-gene-blood.html Cancer Mon, 14 Jan 2013 10:28:20 EST news277381693 A research study from Nanyang Technological University (NTU) has yielded important breakthroughs on how the body loses muscle, paving the way for new treatments for aging, obesity and diabetes. http://medicalxpress.com/news/2012-12-ways-muscle-loss-obesity-diabetes.html Medical research Wed, 19 Dec 2012 09:19:57 EST news275131190 Scientists at Dana-Farber Cancer Institute have isolated a previously unknown protein in muscles that spurs their growth and increased power following resistance exercise. They suggest that artificially raising the protein's levels might someday help prevent muscle loss caused by cancer, prolonged inactivity in hospital patients, and aging. http://medicalxpress.com/news/2012-12-scientists-linking-bigger-stronger-muscles.html Medical research Thu, 06 Dec 2012 12:00:48 EST news274004883 Researchers have identified a new technique that can help determine the severity of muscle loss in critically ill patients. The breakthrough could lead to new research to help prevent muscle-wasting and new therapeutic interventions to help treat critically ill patients. http://medicalxpress.com/news/2012-09-technique-degree-muscle-critically-ill.html Diseases, Conditions, Syndromes Sun, 02 Sep 2012 13:54:24 EST news265812856 (Medical Xpress) -- Cachexia, a syndrome characterized by rapid weight loss and muscle deterioration, is a major cause of death among patients suffering from diseases like cancer, AIDS and chronic infection. In fact, 30 per cent of cancer-related deaths are the result of cachexia-induced muscle loss rather than the primary malignancy. And while scientists are making strides in gaining a better understanding of this deadly condition, no effective anti-cachectic therapies exist to date. However, a newly published study by McGill University researchers shows that a low dose of Pateamine A (PatA) is effective at preventing cancer-induced muscle wasting – findings that could someday point to the development of cachexia-fighting drugs. http://medicalxpress.com/news/2012-06-tool-combat-cachexia-induced-muscle.html Medical research Wed, 13 Jun 2012 07:30:01 EST news258790639 Nutritional supplements are often associated with athletes and body builders, but a University of Kansas professor is conducting a research project to determine whether they are in fact, effective and if they might be able to help older individuals with muscle loss. http://medicalxpress.com/news/2012-05-professor-supplements-muscles.html Other Thu, 24 May 2012 06:44:29 EST news257060660 A team of Japanese researchers will reveal study results Monday at the Experimental Biology 2012 meeting that show how acupuncture therapy mitigates skeletal muscle loss and holds promise for those seeking improved mobility through muscle rejuvenation. http://medicalxpress.com/news/2012-04-japanese-acupuncture-skeletal-muscle-atrophy.html Medical research Mon, 23 Apr 2012 15:30:01 EST news254397275 (AP) -- A team of American scientists and researchers flew to the Mount Everest region on Friday to set up a laboratory at the base of the world's highest mountain to study the effects of high altitude on humans. http://medicalxpress.com/news/2012-04-scientists-mount-everest.html Medical research Fri, 20 Apr 2012 05:14:51 EST news254117681 It's a natural laboratory for studying heart disease, lung problems, muscle loss, sleeping disorders and new medical technologies. It's also the highest mountain in the world. Mount Everest's extreme altitude puts climbers under the same conditions experienced by patients suffering from heart disease, obesity or advanced age. To take advantage of that, Mayo Clinic researchers are joining an expedition to Everest with National Geographic, The North Face and Montana State University. The Mayo group will monitor up to nine climbers from base camp for the duration of the climb, which will run from mid-April to mid-May. http://medicalxpress.com/news/2012-03-mayo-clinic-climbers-everest-heart.html Sleep apnea Thu, 22 Mar 2012 11:53:42 EST news251635986 Permanent disconnection between nerves and muscles may be the reason behind progressive loss of muscle mass and function in elderly people, Perth-based researchers have found. http://medicalxpress.com/news/2012-02-clues-muscle-elderly-people.html Medical research Fri, 24 Feb 2012 07:00:01 EST news249288240 University of Illinois researchers determined that an adult stem cell present in muscle is responsive to exercise, a discovery that may provide a link between exercise and muscle health. The findings could lead to new therapeutic techniques using these cells to rehabilitate injured muscle and prevent or restore muscle loss with age. http://medicalxpress.com/news/2012-02-triggers-stem-cells-muscle.html Medical research Mon, 06 Feb 2012 12:39:51 EST news247754383 It's not how old but how frail patients are that can predict how well they will fare after a melanoma diagnosis. In fact, young patients in poor health may have worse outcomes than older patients in good shape. http://medicalxpress.com/news/2011-08-patients-underlying-health-linked-worse.html Cancer Tue, 30 Aug 2011 11:26:56 EST news233922395 (AP) -- Baby boomers say their biggest health fear is cancer. Given their waistlines, heart disease and diabetes should be atop that list, too. Boomers are more obese than other generations, a new poll finds, setting them up for unhealthy senior years. http://medicalxpress.com/news/2011-07-poll-obesity-boomers.html Health Mon, 18 Jul 2011 15:13:05 EST news230220770 (PhysOrg.com) -- Fish oil supplements may help prevent muscle loss in breast cancer survivors, according to new University of Queensland research. http://medicalxpress.com/news/2011-04-fish-oil-muscle-loss-breast.html Cancer Tue, 12 Apr 2011 08:02:47 EST news221814090