http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death. http://medicalxpress.com/news/2013-03-parkinson-disease-parkin-neuronal-cell.html Parkinson's & Movement disorders Fri, 01 Mar 2013 11:07:03 EST news281358185 Researchers from King's College London have discovered that neuronal activity can stimulate tau release from healthy neurons in the absence of cell death. The results published by Diane Hanger and her colleagues in EMBO reports show that treatment of neurons with known biological signaling molecules increases the release of tau into the culture medi-um. The release of tau from cortical neurons is therefore a physiological process that can be regulated by neuronal activity. http://medicalxpress.com/news/2013-02-neuronal-tau-healthy-neurons.html Alzheimer's disease & dementia Fri, 15 Feb 2013 11:20:03 EST news280148351 The two infamous proteins, amyloid-beta (Aβ) and tau, that characterize advanced Alzheimer's disease (AD), start healthy neurons on the road to cell death long before the appearance of the deadly plaques and tangles by working together to reactivate the supposedly blocked cell cycle in brain cells, according to research presented on Dec. 17 at the American Society for Cell Biology's Annual Meeting in San Francisco. http://medicalxpress.com/news/2012-12-neurons-die-alzheimer-faulty-cell.html Alzheimer's disease & dementia Mon, 17 Dec 2012 13:00:10 EST news274961394 Scientists searching for ways to develop treatments for Huntington's disease (HD) just got a roadmap that could dramatically speed their discovery process. Researchers at the Buck Institute have used RNA interference (RNAi) technology to identify hundreds of "druggable" molecular targets linked to the toxicity associated with the devastating, ultimately fatal disease. The results from this unprecedented genome-scale screen in a human cell model of HD are published in the November 29, 2012 edition of PLOS Genetics. The work was is a collaboration between Buck Institute faculty members Robert E. Hughes, Ph.D., Sean Mooney, Ph.D., Lisa Ellerby, Ph.D. and Juan Botas, Ph.D. at the Baylor College of Medicine. http://medicalxpress.com/news/2012-11-genome-scale-hundreds-potential-drug-huntington.html Genetics Thu, 29 Nov 2012 17:32:16 EST news273432726 In a study published in the current issue of Restorative Neurology and Neuroscience scientists report that a therapy combining exercise with the neurovascular protective agent S-nitrosoglutathione (GSNO) improved recovery from stroke in a rat model. GSNO is a compound found naturally in the body and it has no known side effects or toxicity. http://medicalxpress.com/news/2012-08-therapy-combining-neuroprotective-agent-victims.html Neuroscience Wed, 15 Aug 2012 12:45:09 EST news264253502 A new study identifies specific cell-stress signaling pathways that link injury of the optic nerve with irreversible vision loss. The research, published by Cell Press in the February 9 issue of the journal Neuron, may lead to new strategies that will help to protect vulnerable neurons in the retina after optic nerve damage and diseases. http://medicalxpress.com/news/2012-02-stress-pathway-potential-therapeutic-vision.html Neuroscience Wed, 08 Feb 2012 12:00:01 EST news247918616 (Medical Xpress) -- When you cut an apple and leave it out, it turns brown. Squeeze the apple with lemon juice, an antioxidant, and the process slows down. http://medicalxpress.com/news/2011-12-antioxidant-potential-alzheimer.html Neuroscience Wed, 14 Dec 2011 05:56:53 EST news243064534