http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Bipolar disorder – where patients experience recurrent episodes of mood disturbance, ranging from extreme elation (mania) to severe depression – is thought to affect roughly 2% of the world's population in its most pronounced forms (bipolar I and II), with milder forms of the disorder affecting another 2%. A new Lancet Series provides a comprehensive overview of the genetics, diagnosis, and treatment of bipolar disorder, outlining future challenges, and debating imminent changes to the criteria that psychiatrists use to diagnose the illness. http://medicalxpress.com/news/2013-05-lancet-series-bipolar-disorder.html Psychology & Psychiatry Thu, 09 May 2013 18:30:02 EST news287337873 A group of researchers from the University of Copenhagen has taken a significant step towards understanding the reasons for both diabetes and growth hormone deficiency. Their new discoveries centre on the body's ability to regulate certain hormones, and their findings have just been published in the respected scientific journal PLOS Biology. http://medicalxpress.com/news/2013-04-explanation-diabetes-poor-growth.html Medical research Tue, 23 Apr 2013 17:01:37 EST news285955270 New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to "rewire" themselves in response to external stimuli and the mechanism by which certain viruses hijack normal cellular processes to facilitate their replication that can ultimately lead to cancer. The research will be published in the April 12, 2013 issue of the Journal of Biological Chemistry. http://medicalxpress.com/news/2013-04-reveals-rx-hpv-hep-cancers.html Medical research Wed, 10 Apr 2013 14:43:34 EST news284823807 Researchers from the Centre for Genomic Regulation (CRG) in Barcelona reprogramme lymphoma and leukaemia cells to halt their malignancy. Resulting cells remain benign even when no longer subjected to treatment and reduce likelihood of developing new tumours. http://medicalxpress.com/news/2013-04-cell-reprogramming-leukaemia-lymphoma.html Cancer Wed, 03 Apr 2013 07:50:47 EST news284194240 A non-invasive imaging technique which may help in the earlier detection of cancer is among the innovative research being presented at BioPIC 2013, a BioPhotonics and Imaging Conference, taking place in Castleknock Hotel and Country Club, Dublin from 25th - 27th March. http://medicalxpress.com/news/2013-03-cancer-brain-imaging-techniques.html Cancer Wed, 27 Mar 2013 09:31:15 EST news283595468 UConn researchers are at the forefront of new discoveries and understanding about the smallest molecules in the body that can have a momentous impact on human health. http://medicalxpress.com/news/2013-03-dna-sequencing-landscape-science-biology.html Genetics Tue, 26 Mar 2013 08:21:37 EST news283504887 Think new discoveries are the bee's knees? This one is even better—this research out of Rhode Island Hospital is the mice's knees. Researchers have found that adding lubricin, a protein that our bodies naturally produce, to the fluid in our joints may reduce the risk of or even prevent osteoarthritis (OA). http://medicalxpress.com/news/2013-03-team-strategy-effectively-osteoarthritis.html Arthritis & Rheumatism Mon, 25 Mar 2013 15:00:22 EST news283435184 A new study suggests that people get frustrated when they are offered the opportunity to cheat or steal and that chance is then taken away from them. http://medicalxpress.com/news/2013-03-denied-chance-people-violent-video.html Psychology & Psychiatry Mon, 11 Mar 2013 11:47:15 EST news282221202 Last month, the National Institutes of Health announced a new collaborative initiative that aims to accelerate the search for biomarkers—changes in the body that can be used to predict, diagnose or monitor a disease—in Parkinson's disease, in part by improving collaboration among researchers and helping patients get involved in clinical studies. http://medicalxpress.com/news/2013-03-effort-parkinson-biomarkers.html Parkinson's & Movement disorders Tue, 05 Mar 2013 12:41:45 EST news281709697 The spread of breast cancer to distant organs within the body, an event that often leads to death, appears in many cases to involve the loss of a key protein, according to UC San Francisco researchers, whose new discoveries point to possible targets for therapy. http://medicalxpress.com/news/2013-01-drug-breast-cancer-metastasis.html Cancer Sun, 27 Jan 2013 13:00:16 EST news278503753 The study, published in PLOS Genetics on 20 December, adds to growing evidence that particular genes are involved in chronic pain and highlights this pathway as a potential target for more effective pain relief treatments for patients. http://medicalxpress.com/news/2012-12-genetic-differences-sensitivity-pain.html Genetics Thu, 20 Dec 2012 17:00:06 EST news275244800 Genomic technology has revolutionized gene discovery and disease understanding in autism, according to an article published in the December 20 issue of the journal Neuron. http://medicalxpress.com/news/2012-12-high-throughput-sequencing-potentially-hundreds-gene.html Genetics Wed, 19 Dec 2012 14:33:25 EST news275149998 Cleveland Clinic researchers from the Lerner Research Institute have uncovered two new genes associated with Cowden syndrome (CS) according to a new study, published today in the online version of the American Journal of Human Genetics. http://medicalxpress.com/news/2012-12-genetic-mutations-cowden-syndrome.html Genetics Thu, 13 Dec 2012 12:00:13 EST news274620353 (Medical Xpress)—John Ioannidis, a researcher at Stanford University has, along with graduate student Joshua Nicholson, published a commentary piece in the journal Nature, taking the National Institutes of Health (NIH) to task for maintaining a system that they say rewards conformity while ignoring innovation. http://medicalxpress.com/news/2012-12-nih-grant-totally-broken.html Other Thu, 06 Dec 2012 08:10:01 EST news274000897 By growing new retinal cells to replace those that have malfunctioned, scientists hope to one day create and fuse entire layers of fresh cells –– a synthetic patch akin to a contact lens –– as a treatment for age-related macular degeneration, the top cause of visual impairment among people over 60. http://medicalxpress.com/news/2012-10-envisioning-approaches-eye-disease-medicine.html Medical research Tue, 16 Oct 2012 13:24:49 EST news269612673 (Medical Xpress)—Researchers at Moffitt Cancer Center and colleagues at the University of South Florida; Duke University; Johns Hopkins University; the Brazilian National Cancer Institute; and the Rio de Janeiro Federal Institute of Education, Science and Technology have discovered that an intricate system to repair DNA damage called the "DNA damage response" (DDR) contains previously unknown components, including proteins that could be targeted as sensitizers for chemotherapy. Some of these targets may already have drugs available that have unrecognized uses in cancer therapy, said the researchers. http://medicalxpress.com/news/2012-10-proteins-dna-response-network-therapies.html Medical research Tue, 16 Oct 2012 04:13:09 EST news269579571 (Medical Xpress)—They haven't cured the common cold yet, but a nationwide "big science" team aims to identify new strategies for orchestrating immune responses to better fight disease. http://medicalxpress.com/news/2012-08-immunological-genome-probe-immune-cell.html Immunology Thu, 30 Aug 2012 09:52:22 EST news265539122 The legal system needs to take greater account of new discoveries in neuroscience that show how a difficult childhood can affect the development of a young person's brain which can increase the risk adolescent crimes, according to researchers. The research will be presented as part of an Economic and Social Research Council seminar series in conjunction with the Parliamentary Office of Science and Technology. http://medicalxpress.com/news/2012-06-children-brain-criminal-law.html Psychology & Psychiatry Mon, 18 Jun 2012 10:58:59 EST news259235167 (AP) -- The clock is ticking: The first National Alzheimer's Plan sets a deadline of 2025 to finally find effective ways to treat, or at least stall, the mind-destroying disease. http://medicalxpress.com/news/2012-05-clock-alzheimer.html Alzheimer's disease & dementia Tue, 15 May 2012 03:28:37 EST news256271289 Ever since the water supply in Walkerton, Ont., was contaminated by E. coli in 2000, Dr. Philip Marsden has been trying to figure out just how a toxin released by that particular strain of the bacteria causes kidney damage in children. http://medicalxpress.com/news/2012-01-cells-therapy-kidney-failure-coli.html Diseases, Conditions, Syndromes Tue, 10 Jan 2012 12:17:24 EST news245420232 New discoveries about follicular lymphoma, a currently intractable form of cancer, highlight the power of functional genomics in cancer gene discovery. A report in the Oct 28th issue of Cell demonstrates how genetic insights can be translated directly into therapies. http://medicalxpress.com/news/2011-10-genomic-cancer-drug.html Cancer Thu, 27 Oct 2011 13:05:37 EST news238939529 Patients at Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare were the first in the nation to participate in a clinical trial to determine the safety, tolerability and effectiveness for usage of a new drug combination consisting of a standard drug called gemcitabine and a drug called nab-paclitaxel for patients with advanced pancreatic cancer. http://medicalxpress.com/news/2011-10-results-drug-pancreatic-cancer-patients.html Cancer Tue, 04 Oct 2011 17:20:58 EST news236967650