http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Recent research has shown that cancer cells have a much different – and more complex – metabolism than normal cells. Now, scientists at The University of Texas at Dallas have found that exploiting these differences might provide a new strategy to combat lung cancer. http://medicalxpress.com/news/2013-06-approach-lung-cancer.html Cancer Tue, 18 Jun 2013 16:48:41 EST news290792913 (Medical Xpress)—A major discovery involving a cellular competition and space compensation mechanism within tissues is the subject of an article published May 27 in Developmental Cell by a research team at Florida State University. http://medicalxpress.com/news/2013-05-cellular-competition-space-compensation.html Medical research Wed, 29 May 2013 08:08:08 EST news289033677 Dana-Farber Cancer Institute scientists and colleagues have discovered that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control the deadly cancer. http://medicalxpress.com/news/2013-03-scientists-potential-loophole-pancreatic-cancer.html Cancer Wed, 27 Mar 2013 14:00:07 EST news283606570 A compound that stimulates the production of a tumor-fighting protein may improve the usefulness of the protein in cancer therapy, according to a team of researchers. http://medicalxpress.com/news/2013-02-compound-tumor-fighting-protein-cancer-therapy.html Cancer Wed, 06 Feb 2013 15:19:06 EST news279386339 DNA, like houses and cars, needs ongoing maintenance. Rays of ultraviolet sunlight, chemical pollutants and normal biochemical processes in the cell can damage it. Cells routinely repair this damage before making proteins or copying DNA for cell division. The repairs are remarkably accurate in normal cells but cancer cells make far more mistakes in fixing their DNA. Alan Tomkinson, PhD, University of New Mexico Professor of Internal Medicine and Associate Director of Basic Research at the UNM Cancer Center, wants to understand why and how these repair mechanisms go awry in cancer cells. This understanding could lead to new targets for cancer drugs. Dr. Tomkinson recently won a 4-year $1 million grant renewal to continue his 18-year research investigation on DNA ligases, the enzymes that repair DNA strands. http://medicalxpress.com/news/2012-12-abnormal-dna-maintenance-cancer.html Cancer Mon, 10 Dec 2012 13:18:24 EST news274367890 Cancer cells grow fast. That's an essential characteristic of what makes them cancer cells. They've crashed through all the cell-cycle checkpoints and are continuously growing and dividing, far outstripping our normal cells. To do this they need to speed up their metabolism. http://medicalxpress.com/news/2012-10-team-antisense-technology-exploits-gene.html Cancer Wed, 31 Oct 2012 20:20:08 EST news270930907 Whitehead Institute researchers have found that increased expression of a specific set of genes is strongly associated with metastasis and death in patients with breast, colon, and lung cancers. Not only could this finding help scientists identify a gene profile predictive of patient outcomes and response to treatment, it could also guide the development of therapeutics to target multiple cancer types. http://medicalxpress.com/news/2012-08-heat-shock-factor-reveals-unique-role.html Cancer Thu, 02 Aug 2012 12:00:02 EST news263127408 Investigators reporting in the July issue of the journal Cancer Cell have found that blocking a fundamental process deep within cancer cells can selectively kill them and spare normal cells. http://medicalxpress.com/news/2012-07-deep-cancer-cells.html Cancer Mon, 09 Jul 2012 12:00:12 EST news261052876 Research from Queen Mary, University of London has uncovered the mechanism which causes normal cells to develop into cancer, giving hope in the fight against one of the UK's biggest killers. http://medicalxpress.com/news/2012-03-cancer-early-stages.html Cancer Mon, 26 Mar 2012 17:37:33 EST news252002236 A new discovery published online in The FASEB Journal may lead to a new tool to help physicians assess breast cancer risk as well as diagnose the disease. In the report, researchers from Johns Hopkins University and the University of Maryland, explain how proteins, called "obscurins," once believed to only be in muscle cells, act as "tumor suppressor genes" in the breast. When their expression is lost, or their genes mutated in epithelial cells of the breast, cancer develops. It promises to tell physicians how breast cancer develops and/or how likely it is. http://medicalxpress.com/news/2012-03-obscurins-breast-tissue-physicians-cancer.html Cancer Wed, 21 Mar 2012 14:36:57 EST news251559405 In a major step that could revolutionize biomedical research, scientists have discovered a way to keep normal cells as well as tumor cells taken from an individual cancer patient alive in the laboratory — which previously had not been possible. Normal cells usually die in the lab after dividing only a few times, and many common cancers will not grow, unaltered, outside of the body. http://medicalxpress.com/news/2011-12-discovery-significantly-biomedical.html Cancer Mon, 19 Dec 2011 04:49:24 EST news243492543 Just as people's bodies and minds can become addicted to substances such as drugs, caffeine, alcohol, their cancers can become addicted to certain genes that insure their continued growth and dominance. http://medicalxpress.com/news/2011-12-oncogene-cancer-cell-treatment.html Cancer Thu, 08 Dec 2011 14:00:02 EST news242573362 A research team led by UT Southwestern Medical Center scientists has identified an atypical metabolic pathway unique to some tumors, possibly providing a future target for drugs that could reduce or halt the spread of cancer. http://medicalxpress.com/news/2011-11-tumor-specific-pathway.html Cancer Tue, 22 Nov 2011 10:04:08 EST news241178637