http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress)—A team of researchers at Indiana University's School of Medicine has found that giving meloxicam, a non-steroidal anti-inflammatory drug (NSAID), to people and baboons boosts the number of haematopoietic stem cells that enter the blood stream from bone marrow. This, the team writes in their paper they've had published in the journal Nature, may help cancer patients recover their ability to create new blood cells following chemotherapy. http://medicalxpress.com/news/2013-03-nsaids-stem-cells-bloodstream-prior.html Medical research Thu, 14 Mar 2013 08:37:33 EST news282469042 Osteoarthritis is a progressive joint disease that affects approximately one third of individuals age 65 and older. The disorder causes gradual loss of joint cartilage and bony degeneration while simultaneously creating new bone formation, or bone spurs. The end result of this cascade is joint stiffness, loss of motion and pain. In addition, some individuals also experience irritation of the joint lining, synovitis, which causes painful accumulation of excess joint fluid. http://medicalxpress.com/news/2013-02-nonsurgical-treatment-osteoarthritis-discussed.html Diseases, Conditions, Syndromes Tue, 05 Feb 2013 06:54:10 EST news279269643 Sick children, especially those with some dehydration from flu or other illnesses, risk significant kidney injury if given drugs such as ibuprofen and naproxen, Indiana University School of Medicine researchers said Friday. http://medicalxpress.com/news/2013-01-non-steroidal-anti-inflammatory-drugs-kidney-failure.html Medications Fri, 25 Jan 2013 00:00:01 EST news278272980 (HealthDay)—Nonsteroidal anti-inflammatory drugs (NSAIDs) aggravate exercise-induced small intestinal injury in athletes, according to a study published in the December issue of Medicine & Science in Sports & Exercise. http://medicalxpress.com/news/2012-12-nsaids-exacerbate-exercise-induced-small-intestinal.html Other Wed, 12 Dec 2012 14:30:01 EST news274541237 (HealthDay)—There appears to be no association between persistent pulmonary hypertension of the newborn (PPHN) and gestational exposure to nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, according to a study published online Dec. 3 in Pediatrics. http://medicalxpress.com/news/2012-12-fetal-nsaid-exposure-tied-persistent.html Pediatrics Mon, 03 Dec 2012 16:59:13 EST news273776344 Researchers found that aspirin use is associated with a decreased risk of developing hepatocellular carcinoma and death from chronic liver disease (CLD), according to a study published November 28 in the Journal of the National Cancer Institute. http://medicalxpress.com/news/2012-11-nsaid-linked-hepatocellular-carcinoma-mortality.html Cancer Wed, 28 Nov 2012 16:28:03 EST news273342452 Daily low dose aspirin could slow the decline in brain power among elderly women at high risk of heart disease, indicates observational research published in the online journal BMJ Open. http://medicalxpress.com/news/2012-10-aspirin-temper-brain-power-decline.html Medications Wed, 03 Oct 2012 18:30:04 EST news268504639 Aspirin, the everyday drug taken by countless people around the world to ward off pain and reduce their risk of developing heart disease, may have a new trick up its sleeve –-preventing cancer. http://medicalxpress.com/news/2012-10-aspirin-cancer.html Cancer Mon, 01 Oct 2012 03:32:37 EST news268281147 Dr. Anglea Wandinger-Ness and Dr. Laurie Hudson were awarded a Provocative Questions grant to investigate the use of R-ketorolac against ovarian cancer. Ketorolac is an NSAID that the FDA approved for human use in 1991. They are investigating their hypothesis that R-ketorolac, and not S-ketorolac, acts on GTPases in the cell to control cell adhesion and growth in ovarian cancer cells. http://medicalxpress.com/news/2012-09-drug.html Medications Thu, 27 Sep 2012 13:44:25 EST news267972257 For those suffering from osteoarthritis of the knees or hands, applying topical non-steroidal anti-inflammatory drugs (NSAIDs)—in the form of creams, gels and patches—can bring weeks of pain relief, finds a new review by The Cochrane Library. http://medicalxpress.com/news/2012-09-topical-nsaids-relief-arthritis-pain.html Arthritis & Rheumatism Wed, 19 Sep 2012 09:50:42 EST news267267035 (Medical Xpress)—Headache? Back pain? At the first sign of pain, you might reach for a pain-relieving medicine to sooth your bodily woes. http://medicalxpress.com/news/2012-09-analgesics-linked-loss-women.html Medications Wed, 12 Sep 2012 11:59:43 EST news266669949 Heart attack survivors who take common painkillers after a heart attack have a higher long-term risk of dying or having a second heart attack, according to a new study published in Circulation, an American Heart Association journal. http://medicalxpress.com/news/2012-09-painkillers-death-heart-survivors.html Cardiology Mon, 10 Sep 2012 16:00:04 EST news266501155 Aspirin use appears to reduce the risk of Barrett's esophagus (BE), the largest known risk factor for esophageal cancer, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. http://medicalxpress.com/news/2012-07-aspirin-barrett-esophagus.html Cancer Mon, 23 Jul 2012 12:31:36 EST news262265452 Research published today in Biomed Central's open access journal Journal of Neuroinflammation suggests that chronic inflammation can predispose the brain to develop Alzheimer's disease. http://medicalxpress.com/news/2012-07-chronic-inflammation-brain-alzheimer-disease.html Alzheimer's disease & dementia Mon, 02 Jul 2012 04:08:32 EST news260420839 (Medical Xpress) -- Recent clinical studies have indicated that long-term usage of non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin can significantly reduce the risk of various cancers — some up to 30 per cent.  New findings, published today in Current Biology, provides fresh evidence into their protective properties. http://medicalxpress.com/news/2012-06-scientists-mechanisms-aspirin-cancer.html Cancer Fri, 01 Jun 2012 07:27:34 EST news257754437 A new study suggests that aspirin and other similar painkillers may help protect against skin cancer. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the findings indicate that skin cancer prevention may be added to the benefits of these commonly used medications. http://medicalxpress.com/news/2012-05-commonly-painkillers-skin-cancer.html Cancer Tue, 29 May 2012 03:35:27 EST news257481285 To relieve pain, arthritis sufferers are prescribed medications that may include non-steroidal anti-inflammatory drugs (NSAIDs) or cyclooxygenase-2 (COX-2) inhibitors, both of which can irritate the digestive tract. At times additional drugs are co-prescribed with NSAIDs or COX-2 inhibitors to prevent adverse gastrointestinal (GI) effects. Now a new study available today in the American College of Rheumatology journal, Arthritis & Rheumatism, reveals that decreasing gastroprotective agent (GPA) adherence among users of COX-2 inhibitors is linked to an increased risk of such upper GI complications. http://medicalxpress.com/news/2012-04-gastroprotective-drugs-anti-inflammatory-medicines.html Arthritis & Rheumatism Mon, 16 Apr 2012 03:57:14 EST news253766693 Prescribing opioids for pain to older patients within seven days of short-stay surgery appears to be associated with long-term analgesic use compared to those patients who did not receive prescriptions for analgesics after surgery, according to a study published in the March 12 issue of Archives of Internal Medicine. http://medicalxpress.com/news/2012-03-opioids-pain-short-stay-surgery-long-term.html Medications Mon, 12 Mar 2012 16:00:08 EST news250779581 Patients with recent use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDS), or anti-clotting drugs such as clopidogreal (Plavix) do not appear to have an increased risk of bleeding during or after removal of precancerous lesions in the digestive tract, according to results of a Mayo Clinic study. The findings, culled from a review of 1,382 procedures of patients treated at Mayo Clinic in Florida, are being presented at the annual meeting of the American College of Gastroenterology in Washington, D.C. http://medicalxpress.com/news/2011-11-anti-clotting-drugs-gi-procedure.html Cardiology Tue, 01 Nov 2011 13:39:20 EST news239373550 Use of acetaminophen and nonaspirin nonsteroidal anti-inflammatory drugs was associated with a significantly increased risk for developing renal cell carcinoma, according to data presented at the 10th AACR International Conference on Frontiers in Cancer Prevention Research, held Oct. 22-25, 2011. http://medicalxpress.com/news/2011-10-analgesics-renal-cell-carcinoma.html Cancer Mon, 24 Oct 2011 17:56:54 EST news238697779 Postmenopausal women who reported having used nonsteroidal anti-inflammatory drugs for at least 10 years at the time of enrollment in the Women's Health Initiative study had a lower risk for death from colorectal cancer compared with women who reported no use of these drugs at enrollment, according to data presented at the 10th AACR International Conference on Frontiers in Cancer Prevention Research, held Oct. 22-25, 2011. http://medicalxpress.com/news/2011-10-nsaid-colorectal-cancer-mortality-postmenopausal.html Cancer Mon, 24 Oct 2011 04:27:49 EST news238649261 A team led by scientists from The Scripps Research Institute has identified a new metabolic pathway for controlling brain inflammation, suggesting strategies for treating it. http://medicalxpress.com/news/2011-10-inflammation-differently-brain-tissues.html Medical research Thu, 20 Oct 2011 14:00:12 EST news238330579 A study, in mice, by investigators at the Stanford University School of Medicine points toward potential new therapies for stroke, the nation's third-leading cause of death and foremost single cause of severe neurological disability. The study, which will be published online Oct. 3 in the Journal of Clinical Investigation, also may reveal why a much-heralded class of blockbuster drugs failed to live up to their promise. http://medicalxpress.com/news/2011-10-cox-inhibitors-class-drugs.html Medical research Mon, 03 Oct 2011 12:00:03 EST news236861802 A new study from Rhode Island Hospital researchers suggests that controlling cholesterol may be important for heart health in patients who are taking non-steroidal anti-inflammatory drugs (NSAIDs) such as naproxen. The findings are based on a study on the safety of NSAID medications in clinically relevant animal models when high cholesterol is a factor. The study is published in the current issue of the journal Surgery. http://medicalxpress.com/news/2011-09-cardiovascular-nsaid.html Cardiology Mon, 26 Sep 2011 12:22:54 EST news236258556 Ibuprofen, naproxen, and related non-steroidal anti-inflammatory drugs (NSAIDs) – the subjects of years of study – still have some secrets to reveal about how they work. http://medicalxpress.com/news/2011-09-ibuprofen-actions.html Medical research Sun, 25 Sep 2011 13:17:26 EST news236175432 Long-term use of nonaspirin anti-inflammatory drugs (NSAIDs) is associated with an increased risk of renal cell cancer (RCC), according to a report in the September issue of Archives of Internal Medicine. http://medicalxpress.com/news/2011-09-association-long-term-nonaspirin-anti-inflammatory-drugs.html Inflammatory disorders Mon, 12 Sep 2011 16:31:19 EST news235063855 The risk of miscarriage is 2.4 times greater for women who took any type and dosage of nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs) in early pregnancy, according to a study in CMAJ (Canadian Medical Association Journal). http://medicalxpress.com/news/2011-09-anti-inflammatory-drugs-early-pregnancy-miscarriage.html Health Tue, 06 Sep 2011 12:27:48 EST news234530683 During involution -- the process during which milk-producing cells are killed and replaced by fat cells -- the breast is especially susceptible to the development of aggressive cancers. This study shows that NSAIDs like ibuprofen reduce the severity of these cancers. http://medicalxpress.com/news/2011-08-common-class-pain-drugs-severity.html Cancer Thu, 11 Aug 2011 16:51:30 EST news232300260 Commonly used painkillers to treat inflammation are linked to an increased risk of irregular heart rhythm (known as atrial fibrillation or flutter), concludes a study published in the British Medical Journal today. http://medicalxpress.com/news/2011-07-common-painkillers-linked-irregular-heart.html Medications Mon, 04 Jul 2011 18:30:01 EST news229009494 Results from a UK health-care practitioner (HCP) study presented today at the EULAR 2011 Annual Congress outline a lack of uniform practice between health-care professionals (HCPs) and highlight a strong need for guidelines on the treatments prescribed to patients with rheumatic conditions during conception, pregnancy and during the breastfeeding period. http://medicalxpress.com/news/2011-05-uk-survey-differences-clinicians-rheumatology.html Diseases, Conditions, Syndromes Thu, 26 May 2011 08:07:03 EST news225616009