http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. MIAMI—The stem cell transplant regimen that was commonly used in the United States to treat advanced neuroblastoma in children appears to be more toxic than the equally effective regimen employed in Europe and Egypt, according to a new study being presented at the 26th annual meeting of the American Society of Pediatric Hematology Oncology in Miami April 24-27. The U.S. regimen was associated with more acute toxicity to the kidneys and liver. http://medicalxpress.com/news/2013-04-toxicity-differences-decision-conditioning-neuroblastoma.html Cancer Wed, 24 Apr 2013 13:30:02 EST news286025901 When the eye cancer retinoblastoma is diagnosed in racial and ethnic minority children whose families don't have private health insurance, it often takes a more invasive, potentially life-threatening course than in other children, probably because of delays in diagnosis, Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) researchers will report at the 26th annual meeting of the American Society of Pediatric Hematology Oncology being held in Miami, April 24-27. http://medicalxpress.com/news/2013-04-diagnosis-worsen-outlook-minority-uninsured.html Cancer Wed, 24 Apr 2013 13:30:01 EST news286025989 (HealthDay)—Intraperitoneal (IP) chemotherapy is associated with improved survival in advanced ovarian cancer compared with standard intravenous (IV) therapy, according to a study presented at the Society of Gynecologic Oncology's Annual Meeting on Women's Cancer, held from March 9 to 12 in Los Angeles. http://medicalxpress.com/news/2013-03-sog-intraperitoneal-chemo-ups-ovarian.html Cancer Tue, 12 Mar 2013 12:30:01 EST news282308471 (Medical Xpress)—Patients with advanced, recurrent, or persistent cervical cancer that was not curable with standard treatment who received the drug bevacizumab (Avastin) lived 3.7 months longer than patients who did not receive the drug, according to an interim analysis of a large, randomized clinical trial. http://medicalxpress.com/news/2013-02-bevacizumab-significantly-survival-patients-recurrent.html Cancer Fri, 08 Feb 2013 07:50:01 EST news279531567 (HealthDay)—Current recommendations for the assessment and management of female reproductive complications following treatment of cancers in childhood, adolescence, and young adulthood have been updated, according to a review published online Feb. 4 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2013-02-guidelines-young-ca-survivors-fertility.html Cancer Tue, 05 Feb 2013 13:09:54 EST news279292182 After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked the disease's reemergence to specific genetic anomalies. http://medicalxpress.com/news/2013-02-mutations-linked-relapse-childhood-leukemia.html Genetics Sun, 03 Feb 2013 13:00:04 EST news279114848 About 75 percent of children with leukemia who take chemotherapy face life-threatening heart problems as they age, but an international study led by a University of Rochester Medical Center investigator shows that giving a cardio-protective drug during cancer treatment may prevent the damage. http://medicalxpress.com/news/2012-06-drug-hearts-childhood-leukemia-survivors.html Cancer Mon, 04 Jun 2012 10:52:58 EST news258025955 (HealthDay) -- Ten-year data from the Southwestern Oncology Group-directed Intergroup Study 0116 confirm the benefits of adjuvant radiochemotherapy after gastric cancer resection in terms of overall survival (OS) and relapse-free survival (RFS), according to research published online May 14 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-05-adjuvant-radiochemotherapy-benefit-gastric-cancer.html Cancer Fri, 18 May 2012 13:10:01 EST news256563770 A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma. http://medicalxpress.com/news/2012-05-children-cancer-responses-oncology-group.html Cancer Thu, 17 May 2012 04:59:33 EST news256449566 Preoperative treatment with aromatase inhibitors increases the likelihood that postmenopausal women with estrogen receptor-positive breast cancer will be able to have breast-conserving surgery rather than a mastectomy, according to the results of a national clinical trial presented today at the Society of Surgical Oncology annual meeting in Orlando, Fla. http://medicalxpress.com/news/2012-03-preoperative-estrogen-blocking-therapy-preempt-mastectomy.html Cancer Fri, 23 Mar 2012 09:22:17 EST news251713260 A study by the Children's Oncology Group (COG) reported that five-year survival for acute lymphoblastic leukemia (ALL, the most common type of pediatric cancer) among children treated through COG clinical trials increased from 83.7 percent during the period 1990-1994 to 90.4 percent in the period 2000-2005. The improvements in survival were observed among all children over age 1 regardless of age, sex, ethnicity, or subtype of ALL. This analysis, which is the largest study to date of ALL survival, showed similar gains in 10-year survival. The findings are published March 12 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-03-steady-long-term-survival-children-acute.html Cancer Mon, 12 Mar 2012 16:00:09 EST news250779264 Hispanic children are more likely than those from other racial and ethnic backgrounds to be diagnosed with acute lymphoblastic leukemia (ALL) and are more likely to die of their disease. Work led by St. Jude Children's Research Hospital scientists has pinpointed genetic factors behind the grim statistics. http://medicalxpress.com/news/2012-01-inherited-factors-childhood-leukemia-common.html Cancer Mon, 30 Jan 2012 17:02:48 EST news247165360