https://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine. Scientists from the University of Sheffield are part of an international collaboration to develop a new class of drugs to treat a common genetic kidney disease which is a major cause of kidney failure. https://medicalxpress.com/news/2019-06-drug-compound-tackle-major-life-limiting.html Tue, 18 Jun 2019 09:06:31 EDT news480067583 National Institutes of Health researchers and their colleagues have identified how resveratrol, a naturally occurring chemical found in red wine and other plant products, may confer its health benefits. The authors present evidence that resveratrol does not directly activate sirtuin 1, a protein associated with aging. Rather, the authors found that resveratrol inhibits certain types of proteins known as phosphodiesterases (PDEs), enzymes that help regulate cell energy. https://medicalxpress.com/news/2012-02-uncovers-probable-mechanism-underlying-resveratrol.html Thu, 02 Feb 2012 12:00:10 EST news247402648 Giving patients with chronic obstructive pulmonary disease (COPD) newly available oral phosphodiesterase 4 (PDE4) inhibitors, roflumilast or cilomilast, improves lung function and reduces the likelihood of a flareup, but does not increase general quality of life. These are the findings of a new systematic review by Cochrane researchers. https://medicalxpress.com/news/2011-05-phosphodiesterase-inhibitors-marginal-benefits-people.html Wed, 11 May 2011 04:20:01 EDT news224305072