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Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs (miRNAs) before it's dissolved, researchers reported in an early online publication at Nature. http://medicalxpress.com/news/2013-05-oxygen-short-egfr-maturation-cancer-fighting.html Cancer Thu, 23 May 2013 16:30:07 EST news288544056 A study has identified microRNA-155 as a new independent prognostic marker and treatment target in patients with acute myeloid leukemia that has normal-looking chromosomes under the microscope (that is, cytogenetically normal acute myeloid leukemia, or CN-AML). http://medicalxpress.com/news/2013-05-acute-leukemia-marker-treatment.html Cancer Mon, 13 May 2013 16:49:07 EST news287682539 (HealthDay)—Life expectancy of people with aggressive brain cancer may be easier to determine with a new method under development at the University of Alabama at Birmingham, researchers say. http://medicalxpress.com/news/2013-04-gauging-brain-cancer-survival-easier.html Cancer Wed, 10 Apr 2013 19:00:01 EST news284834780 Researchers at Moffitt Cancer Center have determined that the overexpression of microRNA-155 (miR-155), a short, single strand of ribonucleic acid encoded by the miR-155 host gene, promotes the growth of blood vessels in tumors, tumor inflammation, and metastasis. As a therapeutic target, miR-155 could potentially provide a new avenue of treatment when targeted with drugs to suppress its activity. http://medicalxpress.com/news/2013-04-specific-microrna-tumor-growth-cancer.html Cancer Wed, 03 Apr 2013 15:09:37 EST news284220569 Recent studies have demonstrated that molecular-targeted agents, such as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI), may prolong survival of selected patients based on tumor biomarkers. The presence of mutation in the EGFR gene is known as a predictive marker for the response to treatment. However, whether or not these EGFR mutations are prognostic factors for non-small cell lung cancer (NSCLC) has not been known. A recent study published in the February 2013 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, concludes EGFR mutations are not a prognostic factor in surgically resected patients or patients with recurrence treated with conventional therapies. However, after disease recurrence, administration of EGFR tyrosine kinase inhibitors can prolong survival. http://medicalxpress.com/news/2013-01-egfr-mutation-prognostic-factor-non-small.html Cancer Tue, 15 Jan 2013 11:17:07 EST news277471018 Prostate cancer presents a dilemma for patients and the physicians who treat them. Which cancers are essentially indolent and present no risk and which are life threatening? Which can be watched and which need aggressive treatment? http://medicalxpress.com/news/2012-11-coup-tfii-prostate-cancer.html Cancer Wed, 28 Nov 2012 13:00:28 EST news273327643 Leukaemia arises as a result of genetic or epigenetic alterations in blood cells, leading to an aberrant accumulation of undifferentiated blasts. Understanding the molecular pathogenesis and aetiology of infant leukaemia induced by the MLL-AF4 fusion gene was the subject of the Leukaemogenesis project. http://medicalxpress.com/news/2012-10-infant-leukaemia.html Cancer Mon, 15 Oct 2012 07:32:21 EST news269505136 A metabolic protein that nourishes cancer cells also activates tumor-promoting genes by loosening part of the packaging that entwines DNA to make up chromosomes, a team led by scientists at The University of Texas MD Anderson Cancer Center reports in the Aug. 16 issue of Cell. http://medicalxpress.com/news/2012-08-metabolic-protein-wields-phosphate-group.html Cancer Thu, 16 Aug 2012 13:19:53 EST news264341964 Researchers have identified a prognostic marker in the most common form of chronic leukemia that can help to distinguish which patients should start treatment quickly from those who can safely delay treatment, perhaps for years. http://medicalxpress.com/news/2012-06-marker-distinguishes-more-aggressive-less-aggressive-chronic.html Cancer Tue, 12 Jun 2012 11:40:01 EST news258718111 A study has identified microRNA-3151 as a new independent prognostic marker in certain patients with acute leukemia. The study involves patients with acute myeloid leukemia and normal-looking chromosomes (CN-AML). http://medicalxpress.com/news/2012-05-microrna-prognostic-marker-acute-leukemia.html Cancer Mon, 14 May 2012 14:12:58 EST news256223449 Henry Ford Hospital researchers have found that the presence of excess protein in a common urine test is an effective prognostic marker of acute renal failure in patients with severe sepsis. http://medicalxpress.com/news/2012-05-urine-dipstick-accurate-predictor-renal.html Diseases, Conditions, Syndromes Mon, 14 May 2012 10:00:01 EST news256207102 Omega-3 fatty acids may help to reduce the physical harm caused by smoking, according to a new study presented at the World Congress of Cardiology. http://medicalxpress.com/news/2012-04-omega-fatty-acids-physical.html Cardiology Fri, 20 Apr 2012 02:30:01 EST news254105749 Researchers at the Stanford University School of Medicine have used an innovative mathematical technique to find markers that effectively predict how deadly a cancer will be. The discovery, which in this case concerned bladder cancer, could lead to faster, less expensive and more accurate analysis of cancer risk and better treatment of the disease. http://medicalxpress.com/news/2012-01-algorithm-bladder-cancer-marker.html Cancer Tue, 17 Jan 2012 09:06:30 EST news246013580 Among patients with acute coronary syndromes undergoing a procedure such as angioplasty, those who received platelet function tests before receiving antithrombotic therapy to determine appropriate clopidogrel dosing and who had high residual platelet reactivity (platelets resistant to antithrombotic therapy) were at an increased risk of an ischemic event at short- and long-term follow-up of up to 2 years, according to a study in the September 21 issue of JAMA. http://medicalxpress.com/news/2011-09-platelet-function-antithrombotic-treatment-pci.html Diseases, Conditions, Syndromes Tue, 20 Sep 2011 17:00:38 EST news235756819