http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. AIDS experts cautioned Monday against hype of a cure after doctors in the United States suppressed HIV in a child born with the virus by administering a potent drug cocktail shortly after birth. http://medicalxpress.com/news/2013-03-hiv-infancy-caution-experts.html HIV & AIDS Mon, 04 Mar 2013 12:46:36 EST news281623580 (Medical Xpress)—A novel way to image the entire brain's glymphatic pathway, a dynamic process that clears waste and solutes from the brain that otherwise might build-up and contribute to the development of Alzheimer's disease, may provide the basis for a new strategy to evaluate disease susceptibility, according to a research paper published online in The Journal of Clinical Investigation. Through contrast enhanced magnetic resonance imaging (MRI) and other tools, a Stony Brook University-led research team successfully mapped this brain-wide pathway and identified key anatomical clearance routes of brain waste. http://medicalxpress.com/news/2013-02-scientists-image-brain-alzheimer-diagnostic.html Neuroscience Mon, 25 Feb 2013 07:38:50 EST news281000324 (Medical Xpress)—A drug that works through the same brain mechanism as the fast-acting antidepressant ketamine briefly improved treatment-resistant patients' depression symptoms in minutes, with minimal untoward side effects, in a clinical trial conducted by the National Institutes of Health. The experimental agent, called AZD6765, acts through the brain's glutamate chemical messenger system. http://medicalxpress.com/news/2012-12-experimental-agent-briefly-eases-depression.html Psychology & Psychiatry Tue, 11 Dec 2012 08:19:31 EST news274436364 For people using 30-day extended-wear/continuous-wear (EW/CW) contact lenses, replacing lenses at night doesn't lower the risk of complications compared to changing lenses monthly, suggests a study – "The Effect of Daily Lens Replacement During Overnight Wear on Ocular Adverse Events", appearing in the December issue of Optometry and Vision Science, official journal of the American Academy of Optometry. http://medicalxpress.com/news/2012-12-morning-nighttime-affects-adverse-events.html Ophthalmology Mon, 10 Dec 2012 09:36:12 EST news274354509 Johns Hopkins researchers report concrete steps in the use of human stem cells to test how diseased cells respond to drugs. Their success highlights a pathway toward faster, cheaper drug development for some genetic illnesses, as well as the ability to pre-test a therapy's safety and effectiveness on cultured clones of a patient's own cells. http://medicalxpress.com/news/2012-11-advances-stem-cells-personalized-medicine.html Medical research Mon, 26 Nov 2012 15:37:33 EST news273166640 Biologists in Canada have made a medical enzyme using genetically-engineered corn, a feat that could one day slash the cost of treating a life-threatening inherited disease, a journal reported on Tuesday. http://medicalxpress.com/news/2012-09-lab-drug-on-the-cob-rare-disease.html Diseases, Conditions, Syndromes Tue, 18 Sep 2012 12:26:25 EST news267189967 A targeted approach to treating toxoplasmosis, a parasitic disease, shows early promise in test-tube and animal studies, where it prevented the parasites from making selected proteins. When tested in newly infected mice, it reduced the number of viable parasites by more than 90 percent, researchers from the University of Chicago Medicine report in the Proceedings of the National Academy of Sciences. http://medicalxpress.com/news/2012-08-antisense-approach-treatment-parasitic-infections.html Medical research Mon, 13 Aug 2012 15:03:45 EST news264088963 Gene therapy strategies to prevent and treat inherited diseases of the retina that can cause blindness have progressed rapidly. Positive results in animal models of human retinal disease continue to emerge, as reported in several articles published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The articles are available free on the Human Gene Therapy website at http://www.liebertpub.com/hum. http://medicalxpress.com/news/2012-05-advances-inherited-retinal-diseases-highlighted.html Genetics Tue, 08 May 2012 12:51:42 EST news255700295 The antiangiogenic drug pazopanib has demonstrated clinically meaningful activity in patients with refractory urothelial cancer, according to results presented at the AACR Annual Meeting 2012, held here March 31 - April 4. The results also revealed that increases in interleukin-8 levels early after treatment with pazopanib may predict a lack of tumor response to the therapy. http://medicalxpress.com/news/2012-04-biomarker-drug-response-refractory-urothelial.html Cancer Sun, 01 Apr 2012 06:05:21 EST news252479112 New research shows that infectious disease-fighting drugs could be designed to block a pathogen's entry into cells rather than to kill the bug itself. http://medicalxpress.com/news/2012-01-strategy-infectious-diseases.html Medical research Mon, 09 Jan 2012 15:00:10 EST news245325555 Researchers have demonstrated the feasibility of focused fetal gene expression analysis of target genes found in amniotic fluid using Standardized NanoArray PCR (SNAP) technology. This analysis could be used to monitor fetal development, enabling clinicians to determine very early in pregnancy whether fetal organ systems are developing normally. The study appears in the September issue of The Journal of Molecular Diagnostics. http://medicalxpress.com/news/2011-08-genetic-analysis-amniotic-fluid-fetal.html Genetics Mon, 08 Aug 2011 03:50:01 EST news231993381 A new study published today in the journal Science has shown that the childhood disorder Rett syndrome, can be reestablished in adult animals by "switching off" a critical disease causing gene in healthy adult animals. The gene was "switched off" in adult mice by use of a sophisticated genetic trick, resulting in the appearance of behaviors typically seen in Rett syndrome. The leading author Christopher McGraw, MD/PhD student, carried out the study in the laboratory of Dr. Huda Zoghbi, a renowned neuroscientist based at Baylor College of Medicine, and director of the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital in Houston TX. http://medicalxpress.com/news/2011-06-developmental-disease-recreated-adult.html Diseases, Conditions, Syndromes Thu, 02 Jun 2011 17:26:00 EST news226254345 Omega-3 fatty acids, combined with two blood-thinning drugs, significantly changed the blood-clotting process and may reduce the risk of heart attacks in patients with stents in their heart arteries, according to research reported in Arteriosclerosis, Thrombosis and Vascular Biology: Journal of the American Heart Association. http://medicalxpress.com/news/2011-05-omega-artery-disease-heart-patients.html Cardiology Thu, 26 May 2011 16:37:14 EST news225646606