http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. When it comes to a cancer diagnosis, timing can be everything – the sooner it's found, the more treatable it is. But when and how often should someone get screened? http://medicalxpress.com/news/2013-05-gaps-decision-aids-cancer-screening.html Cancer Fri, 10 May 2013 12:23:14 EST news287407277 The volume of cases performed at an institution each year has a direct effect on the outcome of surgical procedures, and should always be considered when looking at the benefits of a technique, according to a team of researchers at Henry Ford Hospital in Detroit. http://medicalxpress.com/news/2013-05-hospital-surgical-volume-procedures.html Cancer Sun, 05 May 2013 16:32:13 EST news286990327 Two researchers at the National Institutes of Health discovered a new genetic link between the rapid growth of healthy fetuses and the uncontrolled cell division in cancer. The findings shed light on normal development and on the genetic underpinnings of common cancers. http://medicalxpress.com/news/2013-04-genetic-link-fetal-growth-cancer.html Genetics Tue, 09 Apr 2013 04:20:29 EST news284700022 (HealthDay)—Colorectal cancer is the second leading cause of cancer death in the United States, but there are ways you can help prevent it, an expert says. http://medicalxpress.com/news/2013-03-colon-cancer-expert.html Cancer Fri, 08 Mar 2013 15:06:37 EST news281977587 Researchers at Moffitt Cancer Center have found a potential targeted therapy for patients with tobacco-associated non-small cell lung cancer. It is based on the newly identified oncogene IKBKE, which helps regulate immune response. http://medicalxpress.com/news/2013-02-moffitt-potential-therapeutic-non-small-cell.html Cancer Fri, 15 Feb 2013 03:17:20 EST news280120593 Work-related stress is not linked to the development of colorectal, lung, breast or prostate cancers, a study published today in BMJ suggests. http://medicalxpress.com/news/2013-02-stress-cancer.html Cancer Thu, 07 Feb 2013 18:30:02 EST news279472501 By harnessing the very qualities that make sickle cell disease a lethal blood disorder, a research team led by Duke Medicine and Jenomic, a private cancer research company in Carmel, Calif., has developed a way to deploy the misshapen red blood cells to fight cancer tumors. http://medicalxpress.com/news/2013-01-sickle-cells-potential-aggressive-cancer.html Cancer Wed, 09 Jan 2013 17:00:06 EST news276961342 Despite the decline in cancer death rates in the U.S., there is an increase in incidence rates for cancers associated with human papillomavirus (HPV) infection and more efforts are needed to increase HPV vaccination coverage levels to prevent the occurrence of these cancers in the future according to a study published January 7 in the Journal of the National Cancer Institute. http://medicalxpress.com/news/2013-01-hpv-associated-cancer-incidence-efforts-hpv.html Cancer Mon, 07 Jan 2013 16:00:03 EST news276772319 The rate of people who seek preventive cancer screenings has fallen over the last ten years in the United States with wide variations between white-collar and blue-collar workers, according to a University of Miami Miller School of Medicine study published on December 27 in the open-access journal Frontiers in Cancer Epidemiology. http://medicalxpress.com/news/2012-12-cancer-screening-decline-years.html Cancer Thu, 27 Dec 2012 02:00:01 EST news275757596 (HealthDay)—For patients with one of five common cancers, 43.6 percent receive at least one prescription of opioids in the last three months of life, according to a study published in the Dec. 10 issue of the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-12-percent-cancer-patients-opioids-life.html Medications Thu, 13 Dec 2012 15:40:01 EST news274633899 Scientists at Dana-Farber Cancer Institute have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, which normally are needed to spur the cancer's growth. They say the finding could lead to a new treatment for prostate cancers that are no longer controlled by hormone-blocking drugs. http://medicalxpress.com/news/2012-12-culprit-castration-resistant-prostate-cancer.html Cancer Thu, 13 Dec 2012 14:19:08 EST news274630741 Discovery of a new drug with high potential to treat Ewing sarcoma, an often deadly cancer of children and young adults, and the previously unknown mechanism behind it, come hand-in-hand in a new study by researchers from Huntsman Cancer Institute (HCI) at the University of Utah. The report appears in today's online issue of the journal Oncogene. http://medicalxpress.com/news/2012-11-treatment-ewing-sarcoma.html Cancer Mon, 26 Nov 2012 13:49:26 EST news273160157 Storing music and photos on distant computers via "cloud" technology is nothing new. But Johns Hopkins researchers are now using this tactic to collect detailed information from thousands of cancer cell samples. The goal is to help doctors make better predictions about how a patient's illness will progress and what type of treatment will be most effective. http://medicalxpress.com/news/2012-11-cancer-cloud-effective-treatment.html Cancer Tue, 06 Nov 2012 13:34:48 EST news271431270 Scientists at Karolinska Institutet in Sweden and the University of Helsinki in Finland have shown that the "switches" that regulate the expression of genes play a major role in the development of cancer. In a study, published in Science, they have investigated a gene region that contains a particular single nucleotide variant associated with increased risk for developing colorectal and prostate cancers – and found that removing this region caused dramatic resistance to tumor formation. http://medicalxpress.com/news/2012-11-scientists-gene-important-cancer.html Cancer Thu, 01 Nov 2012 14:00:37 EST news270997228 The first detailed study to estimate the global impact of cancer on the number of healthy years of life lost by patients has revealed that nearly 170 million years of healthy life were lost because of cancer in 2008, according to an article published Online First in the Lancet. http://medicalxpress.com/news/2012-10-million-years-healthy-life-lost.html Cancer Mon, 15 Oct 2012 18:30:03 EST news269520941 (Medical Xpress)—A new technique that allows scientists to grow lung cancer cells in three dimensions could accelerate discoveries for a type of cancer that has benefited little from scientific research over the last several decades. http://medicalxpress.com/news/2012-10-d-lung-cancer-mimics-real.html Cancer Thu, 11 Oct 2012 07:25:41 EST news269159120 Mental illnesses and addictions take more of a toll on the health of Ontarians than cancer or infectious diseases, according to a new report by the Institute for Clinical Evaluative Sciences and Public Health Ontario – yet this burden could be reduced with treatment, say scientists from Canada's Centre for Addiction and Mental Health (CAMH). http://medicalxpress.com/news/2012-10-high-toll-mental-illness-addictions.html Psychology & Psychiatry Wed, 10 Oct 2012 13:12:53 EST news269093563 A lysophosphatidic acid receptor 1 (LPAR1) inhibitor, known as Debio-0719, suppresses the development of metastases in mice by inducing cancer cell dormancy, according to a study published August 21 in the Journal of the National Cancer Institute. http://medicalxpress.com/news/2012-08-lpa1-inhibition-metastatic-dormancy-mouse.html Cancer Tue, 21 Aug 2012 16:00:07 EST news264782231 Two common viruses known to be associated with human cancers are both present – and may even be collaborating with each other - in most male prostate cancers, a new study suggests. http://medicalxpress.com/news/2012-07-human-papilloma-virus-epstein-barr.html Cancer Tue, 31 Jul 2012 14:47:37 EST news262964836 (Medical Xpress) -- On the complex road to eradicating cancer, controlling or preventing metastatic growth initiated by primary tumors is high on the to-do list. A key area of such research is the development of therapies based on identifying markers of metastasis associated with altered choline metabolism in breast, ovarian, and prostate cancers. Recently, scientists at the Leibniz Research Centre for Working Environment and Human Factors (IfADO), University of Dortmund, Germany, studying the tumor metabolome – the characteristic metabolic phenotype of tumor cells fundamental to the tumor’s metastatic capacity – identified EDI3 (endometrial differential 3) as the enzyme responsible for a decreased glycerophosphocholine (GPC) to phosphocholine (PC) ratio by cleaving GPC to produce choline. The scientists concluded that since inhibiting EDI3 activity corrects the GPC/PC ratio and thereby decreases tumor cell migration capacity, it represents a possible therapeutic modality. http://medicalxpress.com/news/2012-05-limits-growth-scientists-key-metastasis-enabling.html Medical research Tue, 22 May 2012 09:00:01 EST news256893186 Lung cancer is the most lethal cancer in the United States. According to the National Cancer Institute, lung cancer causes more than 150,000 deaths annually and has a survival rate of 16 percent. More Americans die of lung cancer each year than of cervical, breast, colon and prostate cancers combined. http://medicalxpress.com/news/2012-04-lung-cancer-screening-benefit.html Cancer Tue, 10 Apr 2012 09:34:55 EST news253269286 (HealthDay) -- Primary venous thromboembolism prophylaxis with apixaban, an oral direct Factor Xa inhibitor, in ambulatory cancer patients undergoing first- or second-line chemotherapy for advanced or metastatic cancer, is safe and well tolerated, according to a phase II study published online March 12 in the Journal of Thrombosis and Haemostasis. http://medicalxpress.com/news/2012-03-prophylaxis-apixaban-feasible-cancer-patients.html Cancer Thu, 29 Mar 2012 13:09:53 EST news252245375 Researchers at Moffitt Cancer Center in Tampa, Fla., have discovered that the immune response regulator IKBKE (serine/threonine kinase) plays two roles in tobacco-related non-small cell lung cancers. Tobacco carcinogens induce IKBKE and, in turn, IKBKE induces chemotherapy resistance. http://medicalxpress.com/news/2012-02-important-role-tobacco-related-lung-cancers.html Cancer Thu, 09 Feb 2012 12:55:37 EST news248014519 British patients will soon take part in a trial of a Cuban-designed therapeutic lung cancer vaccine, the first of its kind, a company executive announced Thursday. http://medicalxpress.com/news/2011-11-britons-cuban-lung-cancer-vaccine.html Cancer Fri, 25 Nov 2011 05:16:32 EST news241420577 Researchers at the University of Michigan Comprehensive Cancer Center have discovered two cancer-spurring gene rearrangements that may trigger 5 to 7 percent of all breast cancers. http://medicalxpress.com/news/2011-11-genetic-rearrangements-percent-breast-cancers.html Cancer Sun, 20 Nov 2011 13:28:00 EST news241018065 (Medical Xpress) -- Newcastle and Harvard University reseachers have found that blocking a key component of the DNA repair process could extend the use of a new range of 'smart' cancer drugs called PARP inhibitors. http://medicalxpress.com/news/2011-06-breakthrough-smart-drugs-effective-cancer.html Cancer Mon, 27 Jun 2011 08:42:25 EST news228382932 Cancer is crafty. When one avenue driving its growth is blocked by drugs targeting that path, the malignancy often creates a detour, finding an alternative route to get around the roadblock. http://medicalxpress.com/news/2011-06-prostate-cancer-hormone-therapy-survival.html Cancer Tue, 14 Jun 2011 15:06:34 EST news227282778 About half of prostate cancers have a genetic anomaly that appears to make tumor cells responsive to a new class of cancer-fighting drugs, a new study from the University of Michigan Comprehensive Cancer Center finds. http://medicalxpress.com/news/2011-05-prostate-cancers-potentially-benefit-cancer.html Cancer Wed, 18 May 2011 10:13:15 EST news224932386 A new test for prostate cancer that measures levels of prostate specific antigen (PSA) as well as six specific antibodies found in the blood of men with the disease was more sensitive and more specific than the conventional PSA test used today, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center. http://medicalxpress.com/news/2011-05-prostate-cancer-specific-sensitive-psa.html Cancer Mon, 16 May 2011 17:25:51 EST news224785527