http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (HealthDay)—For untreated patients with hepatitis C virus (HCV), treatment with an oral nucleotide inhibitor of HCV polymerase, sofosbuvir, plus ribavirin seems effective for genotypes 1, 2, and 3; and the HCV NS3 protease inhibitor ABT-450, combined with low-dose ritonavir (ABT-450/r) plus the nonnucleoside NS5B polymerase inhibitor ABT-333 and ribavirin, seems effective for genotype 1, according to two studies published in the Jan. 2 issue of the New England Journal of Medicine. http://medicalxpress.com/news/2013-01-interferon-free-therapies-hep-virus.html Diseases, Conditions, Syndromes Thu, 03 Jan 2013 11:00:01 EST news276431532 A combination of anti-HIV drugs has been found to also reduce the risk of recurrent malaria by nearly half among HIV-positive children, according to researchers supported by the National Institutes of Health. http://medicalxpress.com/news/2012-11-hiv-treatment-malaria-recurrence-children.html Diseases, Conditions, Syndromes Wed, 28 Nov 2012 17:00:10 EST news273344123 The HIV protease inhibitor, Nelfinavir, can be used to treat HER2-positive breast cancer in the same capacity and dosage regimen that it is used to treat HIV, according to a study published October 5 in the Journal of the National Cancer Institute. http://medicalxpress.com/news/2012-10-hiv-drug-efficacy-mouse-her2.html Cancer Sat, 06 Oct 2012 07:14:51 EST news268726474 Infants of human immunodeficiency virus 1 (HIV-1) infected mothers who were treated before and after birth with the protease inhibitor lopinavir-ritonavir were more likely to experience adrenal dysfunction, including life-threatening adrenal insufficiency in premature infants, compared with a zidovudine-based regimen, according to a preliminary report in the July 6 issue of JAMA. http://medicalxpress.com/news/2011-07-hiv-medication-adrenal-dysfunction-newborns.html HIV & AIDS Tue, 05 Jul 2011 17:15:09 EST news229104878 The drug telaprevir (Incivek) provides a dramatic improvement in the treatment of the most common form of hepatitis C infection, says an international team of investigators led by Dr. Ira M. Jacobson of NewYork-Presbyterian Hospital/Weill Cornell Medical Center. http://medicalxpress.com/news/2011-06-drug-breakthrough-treatment-hepatitis.html Medications Wed, 22 Jun 2011 17:23:00 EST news227982164 Researchers at the University of California, San Diego, the Medical University of South Carolina and American Life Science Pharmaceuticals of San Diego have demonstrated that oral administration of a cysteine protease inhibitor, E64d, not only reduces the build-up of β-amyloid (Aβ) in the brains of animal models for Alzheimer's disease, but also results in a substantial improvement in memory deficit. http://medicalxpress.com/news/2011-05-potential-drug-candidate-alzheimer-disease.html Diseases, Conditions, Syndromes Tue, 31 May 2011 13:08:33 EST news226066079 Researchers at the University of California, San Diego and Hunter College of the City University of New York (CUNY) have identified potential human molecular targets of the anti-HIV drug Nelfinavir, which may explain why the drug is also effective as a cancer therapy. Their study will be published in the online edition of PLoS Computational Biology on April 28. http://medicalxpress.com/news/2011-04-molecular-hiv-drug-cancer-therapy.html Medications Thu, 28 Apr 2011 18:00:01 EST news223230398