http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A protein known to be a key player in the development of Parkinson's disease is able to enter and harm cells in the same way that viruses do, according to a Loyola University Chicago Stritch School of Medicine study. http://medicalxpress.com/news/2013-04-parkinson-disease-protein-virus.html Parkinson's & Movement disorders Thu, 25 Apr 2013 17:00:01 EST news286122034 As part of a new initiative to speed the search for changes in the body that can help predict, diagnose, or monitor Parkinson's disease, a research team led by Pacific Northwest National Laboratory recently received a grant from the National Institute of Neurological Disorders and Stroke (NINDS). Scientists from PNNL, University of Miami, Baylor College of Medicine, and Rush University have teamed to identify new components of the Lewy bodies that accumulate in the brain during Parkinson's, and then use ultra-sensitive methods to see if any of these proteins have leaked into cerebrospinal fluid or blood. http://medicalxpress.com/news/2013-03-parkinson-puzzle-assay-components-protein.html Parkinson's & Movement disorders Tue, 26 Mar 2013 08:50:02 EST news283505003 (Medical Xpress)—Researchers at the Virginia Commonwealth University Parkinson's and Movement Disorders Center have found that mitochondrial quality and functional capacity play an important role in Parkinson's disease. http://medicalxpress.com/news/2013-03-parkinson-disease-link.html Parkinson's & Movement disorders Tue, 19 Mar 2013 08:05:21 EST news282899112 Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells. The study, which published online today in the journal Nature Neuroscience, could also open up treatment possibilities for both familial Parkinson's and the more common form of Parkinson's that is not inherited. http://medicalxpress.com/news/2013-03-scientists-clean-up-snafu-brain-cells.html Parkinson's & Movement disorders Sun, 03 Mar 2013 13:00:18 EST news281520529 Flinders University researchers have discovered that a protein in the brain may play a role in the development of Parkinson's disease – a common degenerative neurological disorder which affects the control of body movements. http://medicalxpress.com/news/2013-02-early-diagnosis-treatment-parkinson.html Parkinson's & Movement disorders Fri, 15 Feb 2013 10:40:05 EST news280145163 Columbia University Medical Center (CUMC) researchers have identified a protein trafficking defect within brain cells that may underlie common non-familial forms of Parkinson's disease. The defect is at a point of convergence for the action of at least three different genes that had been implicated in prior studies of Parkinson's disease. Whereas most molecular studies focus on mutations associated with rare familial forms of the disease, these findings relate directly to the common non-familial form of Parkinson's. The study was published today in the online edition of the journal Neuron. http://medicalxpress.com/news/2013-02-treatment-non-familial-parkinson.html Parkinson's & Movement disorders Wed, 06 Feb 2013 13:17:15 EST news279379025 A research team in Israel has devised a novel approach to identifying the molecular basis for designing a drug that might one day decrease the risk diabetes patients face of developing Alzheimer's disease. The team will present its work at the 57th Annual Meeting of the Biophysical Society (BPS), held Feb. 2-6, 2013, in Philadelphia, Pa. http://medicalxpress.com/news/2013-02-ii-diabetes-alzheimer.html Alzheimer's disease & dementia Fri, 01 Feb 2013 16:44:17 EST news278959450 (Medical Xpress)—Rice University scientists have discovered a new way to look inside living cells and see the insoluble fibrillar deposits associated with Parkinson's disease. http://medicalxpress.com/news/2012-12-rice-window-parkinson-disease.html Parkinson's & Movement disorders Mon, 17 Dec 2012 07:07:29 EST news274950435 A new understanding of what takes place on the cellular level during the development of neurodegenerative diseases, such as Parkinson's, Alzheimer's, ALS and Huntington's diseases, offers promise towards possible new strategies for combating such diseases, say Hebrew University of Jerusalem researchers. http://medicalxpress.com/news/2012-12-srategies-neurodegenerative-diseases.html Medical research Thu, 06 Dec 2012 10:44:36 EST news274013065 By using a model, researchers at the University of Montreal have identified and "switched off" a chemical chain that causes neurodegenerative diseases such as Huntington's disease, amyotrophic lateral sclerosis and dementia. The findings could one day be of particular therapeutic benefit to Huntington's disease patients. http://medicalxpress.com/news/2012-11-chemical-neurodegenerative-diseases.html Neuroscience Tue, 27 Nov 2012 04:50:39 EST news273214228 New research into the cell-damaging effects of Huntington's disease suggests a potentially new approach for identifying possible therapeutic targets for treating the nerve-destroying disorder. http://medicalxpress.com/news/2012-06-cell-contents-key-toxicity-huntington.html Genetics Wed, 06 Jun 2012 10:50:42 EST news258198628 Two studies by neurological researchers at Rush University Medical Center suggest that, in the future, colonic tissue obtained during either colonoscopy or flexible sigmoidoscopy may be used to predict who will develop Parkinson's disease, a neurodegenerative disorder of aging that that leads to progressive deterioration of motor function due to loss of neurons in the brain that produce dopamine, a neurotransmitter essential to executing movement. http://medicalxpress.com/news/2012-05-colonoscopy-flexible-sigmoidoscopy-parkinson.html Parkinson's & Movement disorders Tue, 15 May 2012 15:00:01 EST news256299941 Repeated stress triggers the production and accumulation of insoluble tau protein aggregates inside the brain cells of mice, say researchers at the University of California, San Diego School of Medicine in a new study published in the March 26 Online Early Edition of the Proceedings of the National Academy of Sciences. http://medicalxpress.com/news/2012-03-chronic-stress-spawns-protein-aggregates.html Alzheimer's disease & dementia Mon, 26 Mar 2012 15:00:11 EST news251981811 Scientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in "mad cow" disease, but is at least 10 times more lethal than larger prion species. This toxic single molecule or "monomer" challenges the prevailing concept that neuronal damage is linked to the toxicity of prion protein aggregates called "oligomers." http://medicalxpress.com/news/2012-02-scientists-lethal-species-prion-protein.html Medical research Thu, 09 Feb 2012 14:57:36 EST news248021728 The same gene mutations linked to inherited, early-onset Alzheimer's disease have been found in people with the more common late-onset form of the illness. http://medicalxpress.com/news/2012-02-genes-linked-early-late-onset-alzheimer.html Alzheimer's disease & dementia Wed, 01 Feb 2012 17:00:03 EST news247336642 The brains of individuals with Alzheimer's disease contain protein aggregates called plaques and tangles, which interfere with normal communication between nerve cells and cause progressive learning and memory deficits. Now, a research team led by Takaomi Saido from the RIKEN Brain Science Institute in Wako has identified a particular fragment of the amyloid precursor protein (APP) that contributes to the formation of plaques in the brain. http://medicalxpress.com/news/2011-12-characterizing-toxic.html Neuroscience Fri, 09 Dec 2011 06:50:02 EST news242635245 A red dye derived from lichens that has been used for centuries to color fabrics and food appears to reduce the abundance of small toxic protein aggregates in Alzheimer's disease. The dye, a compound called orcein, and a related substance, called O4, bind preferentially to small amyloid aggregates that are considered to be toxic and cause neuronal dysfunction and memory impairment in Alzheimer's disease. http://medicalxpress.com/news/2011-12-natural-dye-lichens-combat-alzheimer.html Medical research Fri, 02 Dec 2011 10:20:03 EST news242042259 Researchers at the RIKEN Brain Science Institute (BSI) have discovered a key mechanism responsible for selectively degrading aggregates of ubiquitinated proteins from the cell. Their findings indicate that the capture and removal of such aggregates is mediated by the phosphorylation of a protein called p62, opening the door to new avenues for treating neurodegenerative diseases such as Huntington's disease and Alzheimer's disease. http://medicalxpress.com/news/2011-11-uncovers-brain-cells-degrade-dangerous.html Medical research Mon, 07 Nov 2011 11:04:36 EST news239886270 Researchers at Lund University have discovered a new function for vitamin C. Treatment with vitamin C can dissolve the toxic protein aggregates that build up in the brain in Alzheimer's disease. The research findings are now being presented in the Journal of Biological Chemistry. http://medicalxpress.com/news/2011-08-treatment-vitamin-dissolves-toxic-protein.html Medical research Thu, 18 Aug 2011 10:33:40 EST news232882391 She's a biologist investigating microbial genomics. He studies protein structures using electron microscopy. Put them together and their research opens doors. http://medicalxpress.com/news/2011-06-treatments-alzheimer-parkinson.html Medical research Mon, 06 Jun 2011 11:30:05 EST news226575767