http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. (Medical Xpress) -- New ways that viruses manipulate the human immune response have been revealed in a research paper just published in Nature involving TCD scientists. Dr Orla Mulhern and Professor Andrew Bowie, School of Biochemistry and Immunology based in the Trinity Biomedical Sciences Institute were part of the multi-disciplinary, multi-centre study comprising immunologists, virologists, biochemists and bioinformaticians from across Europe. http://medicalxpress.com/news/2012-08-ways-viruses-affect-human-immune.html Immunology Fri, 03 Aug 2012 07:52:15 EST news263199129 Researchers have identified a potential new pathway in prostate cancer cells by which cancer-driving gene products can be generated, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2012-06-abnormal-gene-product-prostate-cancer.html Cancer Tue, 19 Jun 2012 10:51:59 EST news259321786 The histone de-acetylase (HDAC) inhibitor panobinostat is able to target and destroy triple negative breast cancer, reveals a new study published in BioMed Central's open access journal Breast Cancer Research. Researchers from Tulane University Health Sciences Center have shown that panobinostat was able to destroy breast cancer cells and reduce tumor growth in mice. http://medicalxpress.com/news/2012-05-blocking-dna-hdac-inhibitor-triple.html Cancer Mon, 21 May 2012 03:57:54 EST news256791449 Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR Annual Meeting 2012. http://medicalxpress.com/news/2012-04-pi3kmtor-pathway-proteins-tied-poor.html Cancer Sun, 01 Apr 2012 12:32:10 EST news252502306 Researchers at Winship Cancer Institute are developing a technique to remove cancer cells' defenses against radiation. http://medicalxpress.com/news/2012-03-disabling-cancer-cells-defenses.html Cancer Thu, 15 Mar 2012 14:46:43 EST news251041594 Uncovering the network of genes regulated by a crucial molecule involved in cancer called mTOR, which controls protein production inside cells, researchers at the University of California, San Francisco (UCSF) have discovered how a protein "master regulator" goes awry, leading to metastasis, the fatal step of cancer. http://medicalxpress.com/news/2012-02-analysis-mtor-protein-drugs-defeat.html Cancer Wed, 22 Feb 2012 13:00:06 EST news249137019 Researchers at the Salk Institute have discovered a startling feature of early brain development that helps to explain how complex neuron wiring patterns are programmed using just a handful of critical genes. The findings, published February 3 in Cell, may help scientists develop new therapies for neurological disorders, such as amyotrophic lateral sclerosis (ALS), and provide insight into certain cancers. http://medicalxpress.com/news/2012-02-complex-wiring-nervous-genes-proteins.html Medical research Fri, 10 Feb 2012 16:15:30 EST news248112920 Most research on glioblastoma development, a complicated tumor of the brain with a poor prognosis, has focused on the gene transcription level, but scientists suggest that post-transcriptional regulation could be equally or even more important. http://medicalxpress.com/news/2012-01-scientists-uncover-mechanism-glioblastoma.html Cancer Wed, 18 Jan 2012 03:46:26 EST news246080765 Whitehead Institute scientists have identified conserved, long intervening non-coding RNAs (lincRNAs) that play key roles during embryonic brain development in zebrafish. They also show that the human versions of the lincRNAs can substitute for the zebrafish versions, which implies that the functions of these non-coding RNAs have been retained in humans as well as fish. http://medicalxpress.com/news/2011-12-intervening-non-coding-rnas-pivotal-roles.html Medical research Thu, 22 Dec 2011 12:00:01 EST news243777267 A protein linked to the immune system could play a key role in helping scientists understand how vCJD spreads throughout the body. http://medicalxpress.com/news/2011-12-protein-insight-vcjd.html Medical research Fri, 02 Dec 2011 08:06:00 EST news242035479 Patients with HER2-positive breast cancer may soon have an alternative therapy when they develop resistance to trastuzumab, also known as Herceptin, according to a laboratory finding published in Clinical Cancer Research. http://medicalxpress.com/news/2011-07-therapy-her2-positive-breast-cancer.html Cancer Tue, 26 Jul 2011 13:00:06 EST news230885661 Though we all depend on reading people's faces, each of us sees others' faces a bit differently. Some of us may gaze deeply into another's eyes, while others seem more reserved. At one end of this spectrum people with autism spectrum conditions (ASC) look less at other people's faces, and have trouble understanding others people's feelings. New research published in BioMed Central's open-access journal Molecular Autism has found variations of the cannabinoid receptor (CNR1) gene that alter the amount of time people spend looking at happy faces. http://medicalxpress.com/news/2011-06-happy-genes.html Psychology & Psychiatry Wed, 29 Jun 2011 04:01:45 EST news228538667 In a new study published today in the journal Nature, scientists discovered an entirely new way to change the genetic code. The findings, though early, are significant because they may ultimately help researchers alter the course of devastating genetic disorders, such as cystic fibrosis, muscular dystrophy and many forms of cancer. http://medicalxpress.com/news/2011-06-scientists-override-errant-genetic.html Medical research Wed, 15 Jun 2011 13:00:01 EST news227361434 Working with a group of national and international researchers, scientists from the Florida campus of The Scripps Research Institute have developed a new genetic model of premature aging disorders that could shed light on these rare conditions in humans and provide a novel platform for large-scale screening of compounds to combat these and other age-related diseases. http://medicalxpress.com/news/2011-04-scientists-genetic-premature-aging-diseases.html Genetics Fri, 29 Apr 2011 10:16:37 EST news223290969