http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Repeated stress triggers the production and accumulation of insoluble tau protein aggregates inside the brain cells of mice, say researchers at the University of California, San Diego School of Medicine in a new study published in the March 26 Online Early Edition of the Proceedings of the National Academy of Sciences. http://medicalxpress.com/news/2012-03-chronic-stress-spawns-protein-aggregates.html Alzheimer's disease & dementia Mon, 26 Mar 2012 15:00:11 EST news251981811 Curcumin, a compound found in the spice turmeric, is proving effective at preventing clumping of a protein involved in Parkinson's disease, says a Michigan State University researcher. http://medicalxpress.com/news/2012-03-curcumin-parkinson-disease.html Parkinson's & Movement disorders Tue, 20 Mar 2012 11:41:54 EST news251462476 Drawing on X-ray crystallography and experimental data, as well as a software suite for predicting and designing protein structures, a UC Davis School of Medicine researcher has developed an algorithm that predicts what has been impossible to generate in the laboratory: the conformational changes in voltage-gated sodium channels when they are at rest or actively transmitting a signal in muscle and nerve cells. http://medicalxpress.com/news/2011-12-foster-drug-pain-epilepsy.html Medical research Mon, 12 Dec 2011 16:16:30 EST news242928978 (Medical Xpress) -- Scientists at the Friedrich Miescher Institute for Biomedical Research (FMI) of the Novartis Research Foundation have elucidated the mechanisms underlying the repair of UV-induced damage in DNA, which frequently causes skin cancer. The protein structures additionally determined by these researchers will improve our understanding of how the body protects itself against skin cancer. These studies lay the foundations for the development of a new class of anti cancer agents. The findings were published today in Cell. http://medicalxpress.com/news/2011-11-internal-skin-cancer-uv.html Cancer Thu, 24 Nov 2011 07:55:16 EST news241343677 Antiviral drugs used to target the herpes virus could be effective at slowing the progression of Alzheimer's disease (AD), a new study shows. http://medicalxpress.com/news/2011-10-antiviral-drugs-alzheimer.html Neuroscience Mon, 17 Oct 2011 09:37:09 EST news238062999 Researchers at Emory University School of Medicine have identified a new type of potential anticancer drug. The compound, named FOBISIN, targets 14-3-3 proteins, important for the runaway growth of cancer cells. http://medicalxpress.com/news/2011-09-x-ray-protein-probe-potential-anticancer.html Cancer Mon, 12 Sep 2011 15:52:51 EST news235061547 The September issue of the online scientific journal Acta Crystallographica: Structural Biology and Crystallization Communications (Acta Cryst F) will consist entirely of work done at the Seattle Structural Genomics Center for Infectious Disease (SSGCID), a consortium of researchers from Seattle BioMed, Emerald BioStructures, the University of Washington and Pacific Northwest National Laboratory (PNNL). This free online edition features 30 peer-reviewed manuscripts, describing 40 unique infectious disease protein structures, as well as high-throughput gene-to-structure methodologies developed by SSGCID, and marks only the second time that Acta Cryst F has dedicated an entire issue to a single Structural Genomics center. The elucidation of such a large number of protein structures, all of which are freely available to scientific researchers to study and compare, provides a highly detailed "blueprint" for fighting infectious disease and bioterrorism. http://medicalxpress.com/news/2011-09-genomics-blueprint-infectious-disease-biodefense.html Diseases, Conditions, Syndromes Thu, 01 Sep 2011 13:42:33 EST news234103328 Collaborating researchers at Stanford University and The Scripps Research Institute have identified chemical compounds that show promise as potential therapeutics for a set of medical conditions caused by the abnormal clumping together of a protein known as transthyretin (TTR). http://medicalxpress.com/news/2011-08-scientists-drug-candidates-protein-folding-diseases.html Medical research Mon, 29 Aug 2011 14:45:04 EST news233847868 Telomeres, the body's own cellular clocks, may be a crucial factor underlying the development of emphysema, according to research from Johns Hopkins University. http://medicalxpress.com/news/2011-07-links-telomere-length-emphysema.html Medical research Fri, 15 Jul 2011 03:21:54 EST news229918898 (Medical Xpress) -- University of Michigan researcher Gabrielle Rudenko and her Life Sciences Institute lab have solved the structure of a protein that is implicated in a number of neuropsychiatric disorders including autism spectrum disorder, schizophrenia and mental retardation. http://medicalxpress.com/news/2011-07-revealed-protein-implicated-autism-similar.html Medical research Fri, 08 Jul 2011 07:45:27 EST news229329904 Researchers at the Salk Institute have been able to genetically incorporate "unnatural" amino acids, such as those emitting green fluorescence, into neural stem cells, which then differentiate into brain neurons with the incandescent "tag" intact. http://medicalxpress.com/news/2011-07-unnatural-chemical-protein-action-brain.html Medical research Thu, 07 Jul 2011 14:31:22 EST news229267864 She's a biologist investigating microbial genomics. He studies protein structures using electron microscopy. Put them together and their research opens doors. http://medicalxpress.com/news/2011-06-treatments-alzheimer-parkinson.html Medical research Mon, 06 Jun 2011 11:30:05 EST news226575767 Although all cells in an organism have the same DNA, cells function differently based on the genes they express. While most studies of gene expression focus on activities in the cell's nucleus, a new Cornell study finds that processes outside the nucleus -- along the cell membrane -- also play important roles in gene expression. http://medicalxpress.com/news/2011-05-weill-uncover-basic-cell-pathway.html Genetics Tue, 24 May 2011 07:31:16 EST news225440998