Medical Xpress: PHYSorg news tagged with: randomized clinical trials http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. No evidence drugs, vitamins, supplements help prevent cognitive decline in healthy older adults A review of published research has found no evidence that drugs, herbal products or vitamin supplements help prevent cognitive decline in healthy older adults. http://medicalxpress.com/news/2013-04-evidence-drugs-vitamins-supplements-cognitive.html Health Mon, 15 Apr 2013 16:10:16 EST news285261006 Co-Q10 deficiency may relate to concern with statin drugs, higher risk of diabetes (Medical Xpress)—A laboratory study has shown for the first time that coenzyme Q10 offsets the cellular changes that are linked to a side-effect of some statin drugs - an increased risk of adult-onset diabetes. http://medicalxpress.com/news/2013-04-co-q10-deficiency-statin-drugs-higher.html Diseases, Conditions, Syndromes Wed, 10 Apr 2013 12:40:46 EST news284816434 Feeling hungry may protect the brain against Alzheimer's disease, study finds The feeling of hunger itself may protect against Alzheimer's disease, according to study published today in the journal PLOS ONE. Interestingly, the results of this study in mice suggest that mild hunger pangs, and related hormonal pathways, may be as important to the much-discussed value of "caloric restriction" as actually eating less. http://medicalxpress.com/news/2013-04-hungry-brain-alzheimer-disease.html Alzheimer's disease & dementia Wed, 03 Apr 2013 09:27:10 EST news284200011 Use of adjunctive antipsychotic medications in depression A study published this week in PLOS Medicine finds that while antipsychotic medications are associated with small-to-moderate improvements in depressive symptoms in adults, there is little evidence for improvement on measures of quality of life and these medications are linked to adverse events such as weight gain and sedation. http://medicalxpress.com/news/2013-03-adjunctive-antipsychotic-medications-depression.html Psychology & Psychiatry Tue, 12 Mar 2013 17:00:07 EST news282323089 Clinical trials with nonblinded outcome assessors have high observer bias A new study of randomized clinical trials found significant observer bias toward a more beneficial treatment effect in nonblinded trials when the researcher knew the treatment being given to the participant. The study is published in CMAJ (Canadian Medical Association Journal). http://medicalxpress.com/news/2013-01-clinical-trials-nonblinded-outcome-assessors.html Other Mon, 28 Jan 2013 12:00:07 EST news278588983