http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A small, naturally occurring nucleic acid sequence, called a microRNA, known to regulate a number of different cancers, appears to alter the activity of the androgen receptor, which plays a critical role in prostate cancer. Directly targeting microRNA-125b to block androgen receptor activity represents a novel approach for treating castrate-resistant prostate cancer. This promising new strategy for improving the effectiveness of anti-androgenic and other hormonal therapies is described in an article in BioResearch Open Access. http://medicalxpress.com/news/2012-07-therapeutic-prostate-cancer.html Cancer Tue, 17 Jul 2012 11:27:26 EST news261743239 (Medical Xpress) -- The ability to control whether certain stem cells ultimately become bone cells holds great promise for regenerative medicine and potential therapies aimed at treating metabolic bone diseases. http://medicalxpress.com/news/2012-07-epigenetic-links-cell-fate-decisions-adult.html Genetics Mon, 09 Jul 2012 06:10:20 EST news261032998 The University of Nottingham has begun the search for a new class of injectable materials that will stimulate stem cells to regenerate damaged tissue in degenerative and age related disorders of the bone, muscle and heart. http://medicalxpress.com/news/2012-07-tissue-regeneration-state-of-the-art.html Medical research Fri, 06 Jul 2012 09:31:16 EST news260785859 Regenerative medicine researchers at Wake Forest Baptist Medical Center have reached an early milestone in a long-term project that aims to build replacement kidneys in the lab to help solve the shortage of donor organs. http://medicalxpress.com/news/2012-06-lab-engineered-kidney-early-milestone.html Surgery Thu, 21 Jun 2012 13:40:29 EST news259504787 Cedars-Sinai's Regenerative Medicine Institute has pioneered research on how motor-neuron cell-death occurs in patients with spinal muscular atrophy, offering an important clue in identifying potential medicines to treat this leading genetic cause of death in infants and toddlers. http://medicalxpress.com/news/2012-06-stem-cells-advance-spinal-muscular.html Medical research Wed, 20 Jun 2012 09:45:26 EST news259404305 For the first time scientists have succeeded in taking skin cells from heart failure patients and reprogramming them to transform into healthy, new heart muscle cells that are capable of integrating with existing heart tissue. http://medicalxpress.com/news/2012-05-scientists-patients-skin-cells-heart.html Cardiology Wed, 23 May 2012 04:11:11 EST news256965049 Autologous (self-donated) mononuclear cells derived from bone marrow (BMMNCs) have been found to significantly induce vascular growth when transplanted into patients with diabetes who are suffering from critical limb ischemia caused by peripheral artery disease (PAD), a complication of diabetes. The team of researchers in Seville, Spain who carried out the study published their results in a recent issue of Cell Transplantation (20:10), now freely available on-line. http://medicalxpress.com/news/2012-04-autologous-bone-marrow-derived-mononuclear-cell.html Medical research Wed, 18 Apr 2012 13:14:02 EST news253973634 (Medical Xpress) -- Researchers at the Stanford Institute for Stem Cell Biology and Regenerative Medicine have discovered genetic markers that may ultimately allow women to track and predict declining fertility. http://medicalxpress.com/news/2012-03-genetic-markers-fertility-decline-women.html Obstetrics & gynaecology Tue, 27 Mar 2012 08:38:55 EST news252056325 Scientists have shed light on how the liver repairs itself with research that could help develop drugs to treat liver disease. http://medicalxpress.com/news/2012-03-scientists-liver.html Medical research Sun, 04 Mar 2012 13:00:06 EST news250085612 Diabetes is a major risk factor for cardiovascular disease and can reduce blood supply to the heart tissue and damage cardiac cells, resulting in heart failure. New research has investigated if nerve growth factor (NGF) gene therapy can prevent diabetic heart failure and small vascular disease in mice. http://medicalxpress.com/news/2011-12-nerve-growth-factor-gene-therapy.html Diseases, Conditions, Syndromes Tue, 20 Dec 2011 16:00:04 EST news243619082 The word's first artificial windpipe transplant has been such a success that a second operation has been carried out and a third is being planned, The Lancet reported on Thursday. http://medicalxpress.com/news/2011-11-recipient-artificial-windpipe-graft.html Other Thu, 24 Nov 2011 04:13:56 EST news241330419 Researchers from Mount Sinai School of Medicine have discovered the therapeutic benefit of fetal stem cells in helping the maternal heart recover after heart attack or other injury. The research, which marks a significant advancement in cardiac regenerative medicine, was presented today at the American Heart Association's (AHA) Scientific Sessions 2011 in Orlando, Florida, and is also published in the current issue of Circulation Research, a journal of the AHA. http://medicalxpress.com/news/2011-11-fetal-stem-cells-placenta-maternal.html Cardiology Mon, 14 Nov 2011 17:14:45 EST news240513126 Human colon stem cells have been identified and grown in a lab-plate for the first time. This achievement, made by researchers of the Colorectal Cancer Lab at the Institute for Research in Biomedicine (IRB Barcelona) and published in Nature Medicine, is a crucial advance towards regenerative medicine. http://medicalxpress.com/news/2011-09-scientists-human-intestinal-stem-cell.html Medical research Sun, 04 Sep 2011 13:02:08 EST news234359931 Research at the Australian Regenerative Medicine Institute (ARMI) at Monash University could lay the groundwork for new muscular dystrophy treatments. http://medicalxpress.com/news/2011-07-stem-cell-foundation-muscular-dystrophy.html Medical research Thu, 14 Jul 2011 09:23:34 EST news229854023 For the first time since stem cells were discovered here 50 years ago, scientists have isolated a human blood stem cell in its purest form – as a single stem cell capable of regenerating the entire blood system. This breakthrough opens the door to harnessing the power of these life-producing cells to treat cancer and other debilitating diseases more effectively. The study is published today in Science. http://medicalxpress.com/news/2011-07-pure-human-blood-stem-cell-discovery.html Medical research Thu, 07 Jul 2011 14:00:42 EST news229265448 Researchers at The Saban Research Institute of Children's Hospital Los Angeles have successfully created a tissue-engineered small intestine in mice that replicates the intestinal structures of natural intestine -- a necessary first step toward someday applying this regenerative medicine technique to humans. http://medicalxpress.com/news/2011-07-functioning-small-intestine-laboratory.html Medical research Tue, 05 Jul 2011 17:13:41 EST news229104805 Researchers from Boston University's Center for Regenerative Medicine (CReM) have demonstrated that induced pluripotent stem cells (iPSCs) can differentiate into definitive endoderm cells, in vitro, with similar functional potential when compared to embryonic stem cells (ESCs), despite minor molecular differences between the two cell types. http://medicalxpress.com/news/2011-05-validate-important-roles-ipscs-regenerative.html Medical research Mon, 02 May 2011 15:14:45 EST news223568071 For the first time, scientists at Toronto General Hospital, University Health Network have shown in a clinical trial that the Toronto XVIVO System can safely and effectively treat, re-assess and improve the function of high-risk donor lungs so that they can be successfully transplanted into patients. The use of this technique could significantly expand the donor organ pool and improve outcomes after transplantation. http://medicalxpress.com/news/2011-04-toronto-xviv0-lung-perfusion-high-risk.html Other Wed, 13 Apr 2011 17:41:59 EST news221935308