http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Bacteria resistant to the antibiotic colistin are also commonly resistant to antimicrobial substances made by the human body, according to a study in mBio, the online open-access journal of the American Society for Microbiology. Cross-resistance to colistin and host antimicrobials LL-37 and lysozyme, which help defend the body against bacterial attack, could mean that patients with life-threatening multi-drug resistant infections are also saddled with a crippled immune response. Colistin is a last-line drug for treating several kinds of drug-resistant infections, but colistin resistance and the drug's newfound impacts on bacterial resistance to immune attack underscore the need for newer, better antibiotics. http://medicalxpress.com/news/2013-05-resistance-last-line-antibiotic-bacteria-resistant.html Diseases, Conditions, Syndromes Tue, 21 May 2013 00:00:01 EST news288291710 Experts have warned of the growing risk of travellers to India, China and South East Asia bringing home E.coli infections that are immune to treatment with a normal course of antibiotic tablets. http://medicalxpress.com/news/2013-03-china-india-boosts-antibiotic-resistant.html Diseases, Conditions, Syndromes Mon, 18 Mar 2013 09:10:02 EST news282815492 Governments around the world should stop squandering resources fighting an "unwinnable war" against illegal drugs, such as cocaine and heroin. Instead, they should use the cash to curb antibiotic misuse, which poses a far more serious threat to human health, claims a leading ethicist in the Journal of Medical Ethics. http://medicalxpress.com/news/2013-02-scrap-unwinnable-drugs-war-funds.html Diseases, Conditions, Syndromes Wed, 20 Feb 2013 18:30:03 EST news280602901 A major European and global health issue is resistance to or inappropriate use of antibiotics. The European Centre for Disease Prevention and Control (ECDC) estimates that each year, antimicrobial resistance (AMR) results in 25 000 deaths and related costs of over EUR 1.5 billion in healthcare expenses and productivity losses. Over the last four years, there has been a significant increasing trend of combined resistance to multiple antibiotics in both Klebsiella pneumoniae and E. coli in more than one-third of the EU/EEA countries. In addition, in several Member States, between 25 % and up to more than 60 % of Klebsiella pneumoniae from bloodstream infections show combined resistance to multiple antibiotics. http://medicalxpress.com/news/2013-01-threat-antibiotic-resistance.html Diseases, Conditions, Syndromes Thu, 10 Jan 2013 06:15:02 EST news277020890 As the prevalence of antibiotic-resistant infections continue to rise around the world, a hospital in Canada detected the presence of New Delhi Metallo-ß-lactamase-1-Producing Klebsiella pneumoniae (NDM1-Kp), a multidrug resistant bacteria that is resistant to carbapenems, one of the last lines of antibiotics. The retrospective report, featured in the January issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America, analyzes risk factors and infection control strategies taken to prevent the spread of NDM1-Kp. http://medicalxpress.com/news/2012-12-foreign-multidrug-resistant-bacteria-toronto.html Diseases, Conditions, Syndromes Tue, 11 Dec 2012 10:52:41 EST news274445536 Genome mapping could prove key in preventing superbugs in hospitals, an Australian researcher said Friday, urging its use to prevent countless deaths from antibiotic-resistant infections. http://medicalxpress.com/news/2012-11-genome-superbug-deaths.html Diseases, Conditions, Syndromes Fri, 30 Nov 2012 09:31:14 EST news273490266 (HealthDay)—Americans are not as smart about antibiotics and antibiotic resistance as they should be, a new poll shows. http://medicalxpress.com/news/2012-11-americans-dark-antibiotic-resistance.html Diseases, Conditions, Syndromes Tue, 13 Nov 2012 18:30:11 EST news272048505 Career paths can start to take shape in many unexpected ways. For UCLA physician Daniel Uslan, it all started in a class for kids called "It's a Small World." That's when the five-year-old made sourdough bread with his father. http://medicalxpress.com/news/2012-10-superbugs.html Diseases, Conditions, Syndromes Thu, 11 Oct 2012 06:51:28 EST news269157081 Menachem Shoham, PhD, associate professor of biochemistry at Case Western Reserve University School of Medicine, has discovered novel antivirulence drugs that, without killing the bacteria, render Methicillin Resistant Staphylococcus Aureus (MRSA) and Streptococcus pyogenes, commonly referred to as strep, harmless by preventing the production of toxins that cause disease. The promising discovery was presented this week at the Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco. http://medicalxpress.com/news/2012-09-non-antibiotic-agents-mrsa-common-strep.html Medical research Wed, 12 Sep 2012 13:38:53 EST news266675906 For six months last year, a deadly outbreak of antibiotic-resistant bacteria kept infection-control specialists at the National Institutes of Health's (NIH) Clinical Center in a state of high alert. A New York City patient carrying a multi-drug resistant strain of Klebsiella pneumoniae, a microbe frequently associated with hospital-borne infections, introduced the dangerous bacteria into the 243-bed research hospital while participating in a clinical study in the summer of 2011. http://medicalxpress.com/news/2012-08-genome-sequencing-quell-bacterial-outbreak.html Diseases, Conditions, Syndromes Wed, 22 Aug 2012 14:27:29 EST news264864440 Canada should ban off-label use of antibiotics in farm animals because it contributes significantly to antibiotic resistance in humans, states an editorial in CMAJ (Canadian Medical Association Journal). http://medicalxpress.com/news/2012-06-canada-off-label-antibiotic-agriculture-cmaj.html Diseases, Conditions, Syndromes Mon, 04 Jun 2012 12:00:03 EST news258026289 Curbing unnecessary use of antibiotics is our best defense against the spread of drug-resistant infections. A new study suggests another benefit to antimicrobial stewardship: a potential cost savings of millions of dollars now wasted on therapies that don't help patients. http://medicalxpress.com/news/2012-03-antibiotic-millions.html Diseases, Conditions, Syndromes Thu, 15 Mar 2012 05:14:09 EST news251007206 Shahriar Mobashery, a University of Notre Dame researcher, is one of the coauthors of a new paper by a group of the world's leading scientists in academia and industry that calls for strong steps to be taken to control the global crisis of antibiotic resistance in bacteria. The group issued a priority list of steps that need to be taken on a global scale to resolve the crisis. http://medicalxpress.com/news/2011-12-paper-strong-tackle-antibiotic-resistance.html Medications Thu, 08 Dec 2011 15:41:43 EST news242581293 MGB Biopharma, a biopharmaceutical company which has licensed technology from the University of Strathclyde in Glasgow, Scotland, is developing a powerful new antibiotic treatment for resistant infections including the deadly MRSA and Clostridium difficile (C. diff.) bugs. http://medicalxpress.com/news/2011-09-powerful-diff-treatment.html Diseases, Conditions, Syndromes Mon, 19 Sep 2011 15:49:59 EST news235666182 (Medical Xpress) -- An ongoing study led by a University of Pittsburgh researcher has established the first scientifically-based dosing guidelines for a more than 50-year-old drug that has re-emerged as the best, and often only, treatment for some bacterial infections that are resistant to modern therapies. The study appears in the July issue of the journal Antimicrobial Agents and Chemotherapy. http://medicalxpress.com/news/2011-07-dosing-1950s-drug-drug-resistant-infections.html Medications Mon, 04 Jul 2011 07:05:06 EST news228981859 Short courses of antibiotics appear just as effective as longer ones - and a great deal safer - in treating respiratory infections that might cause pneumonia in children on temporary breathing devices, according to a Johns Hopkins Children's Center study published online May 3 in Clinical Infectious Diseases. http://medicalxpress.com/news/2011-05-short-antibiotic-courses-safer-breathing-tube.html Diseases, Conditions, Syndromes Thu, 05 May 2011 15:29:58 EST news223828168