http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. At TEDxSydney 2013 the Professor of Genetics at Harvard Medical School shares a new concept about why we age and how it should be possible to develop medicines to reverse it. http://medicalxpress.com/news/2013-04-tablet-youth.html Health Tue, 23 Apr 2013 08:41:06 EST news285925231 (HealthDay)—Resveratrol appears not to have a metabolic effect in obese men, according to a study published in the April issue of Diabetes. http://medicalxpress.com/news/2013-04-resveratrol-effect-healthy-obese-men.html Diabetes Mon, 08 Apr 2013 18:00:01 EST news284661538 Resveratrol, a molecule found in red wine (and red grape skin and elsewhere) is back in the headlines after an international team of researchers published a paper in the journal Sciencelate last week. The news made headlines around the world. http://medicalxpress.com/news/2013-03-resveratrol-red-wine-sauce-fountain.html Medical research Wed, 13 Mar 2013 09:40:03 EST news282385275 Drugs that combat ageing may be available within five years, following landmark work led by an Australian researcher. The work, published in the March 8 issue of Science, finally proves that a single anti-ageing enzyme in the body can be targeted, with the potential to prevent age-related diseases and extend lifespans. http://medicalxpress.com/news/2013-03-anti-ageing-drug-breakthrough.html Medical research Fri, 08 Mar 2013 08:10:59 EST news281952653 In the early 1990s, MIT professor Leonard Guarente discovered that sirtuins, a class of proteins found in nearly all animals, protect against the effects of aging in yeast; similar effects have since been seen in many other organisms. In 2003, David Sinclair, who had been a postdoc in Guarente's lab, found that resveratrol, a compound found in grapes and red wine, can also counteract the effects of aging. Since then, many scientists have tried to tease out the exact relationship among sirtuins, resveratrol and aging. http://medicalxpress.com/news/2013-03-mit-biologist-resveratrol.html Medical research Thu, 07 Mar 2013 16:47:20 EST news281897232 New insight into grape seed extract as a therapeutic and preventative measure to fight obesity-induced kidney damage is presented in a new study. Grape seed and skin extract (GSSE) is known to contain powerful antioxidants. This study, published in the journal Applied Physiology, Nutrition, and Metabolism, is the first to make a link between GSSEs and high-fat-diet-induced renal disease. http://medicalxpress.com/news/2013-02-grape-seed-skin-extracta-weapon.html Health Thu, 28 Feb 2013 12:46:48 EST news281277991 Resveratrol, a substance found in red grapes and red wine, may have the potential to protect against hearing and cognitive decline, according to a published laboratory study from Henry Ford Hospital in Detroit. http://medicalxpress.com/news/2013-02-resveratrol-cognition.html Medical research Wed, 20 Feb 2013 13:20:01 EST news280588070 Natural chemicals found in green tea and red wine may disrupt a key step of the Alzheimer's disease pathway, according to new research from the University of Leeds. http://medicalxpress.com/news/2013-02-green-tea-red-wine-alzheimer.html Alzheimer's disease & dementia Tue, 05 Feb 2013 18:00:01 EST news279305737 Researchers at the Universidade Federal in Rio de Janeiro in Brazil have found that introduction of a normal copy of the p53 gene in p53-defective cancer cell lines makes these cells sensitive to the anti-tumor proprieties of resveratrol, the naturally occurring dietary compound found in red wine. http://medicalxpress.com/news/2012-11-resveratrol-full-p53-ingredients-successful.html Medical research Tue, 13 Nov 2012 11:25:45 EST news272028333 Resveratrol, a compound found commonly in grape skins and red wine, has been shown to have several beneficial effects on human health, including cardiovascular health and stroke prevention. Now, a University of Missouri researcher has discovered that the compound can make prostate tumor cells more susceptible to radiation treatment, increasing the chances of a full recovery from all types of prostate cancer, including aggressive tumors. http://medicalxpress.com/news/2012-11-compound-grapes-red-wine-key.html Cancer Sat, 10 Nov 2012 05:46:31 EST news271748770 A natural compound found in some fruits, nuts and red wine may enhance exercise training and performance, demonstrates newly published medical research from the University of Alberta. http://medicalxpress.com/news/2012-06-resveratrol-natural.html Health Tue, 19 Jun 2012 15:10:36 EST news259337354 A national, phase II clinical trial examining the effects of resveratrol on individuals with mild to moderate dementia due to Alzheimer's disease has begun as more than two dozen academic institutions recruit volunteers in the coming months. R. Scott Turner, M.D., Ph.D., director of Georgetown University Medical Center's Memory Disorders Program, is the lead investigator for the national study. http://medicalxpress.com/news/2012-05-georgetown-physician-national-resveratrol-alzheimer.html Alzheimer's disease & dementia Mon, 14 May 2012 03:41:45 EST news256185692 A research team from the Netherlands assessed the impact of wine and resveratrol (a natural polyphenol found in high quantities in red wine) on lung function. It also looked at genetic factors and mechanisms by which resveratrol might be absorbed by the body and its possible effect on longevity of life. The authors report that pure resveratrol intake was associated with higher lung volumes and that white wine intake (but not red wine intake) and was associated with lower risk of airway obstruction. They report that the genetic factors studied did not relate to the associations found. http://medicalxpress.com/news/2012-03-moderate-wine-consumption-lung-function.html Health Thu, 08 Mar 2012 10:49:48 EST news250426178 A well-conducted experimental study in mice has provided potentially important new insights into the association of the intake of resveratrol and like compounds with health benefits. Resveratrol is a constituent of red wine and other vegetable products, and is being evaluated in high-doses as a pharmaceutical. The biologic mechanisms demonstrated in this study could provide key new approaches for the prevention or treatment of a number of chronic diseases in humans, especially those related to vascular and metabolic diseases and to the risk of mortality. http://medicalxpress.com/news/2012-02-potentially-important-mechanisms-anti-aging-effects.html Medical research Thu, 09 Feb 2012 13:10:42 EST news248015431 National Institutes of Health researchers and their colleagues have identified how resveratrol, a naturally occurring chemical found in red wine and other plant products, may confer its health benefits. The authors present evidence that resveratrol does not directly activate sirtuin 1, a protein associated with aging. Rather, the authors found that resveratrol inhibits certain types of proteins known as phosphodiesterases (PDEs), enzymes that help regulate cell energy. http://medicalxpress.com/news/2012-02-uncovers-probable-mechanism-underlying-resveratrol.html Medical research Thu, 02 Feb 2012 12:00:10 EST news247402648 When obese men take a relatively small dose of resveratrol in purified form every day for a month, their metabolisms change for the better. In fact, the effects appear to be as good for us as severe calorie restriction. Resveratrol is a natural compound best known as an ingredient in red wine. http://medicalxpress.com/news/2011-11-clinical-trial-red-wine-ingredient.html Medical research Tue, 01 Nov 2011 12:44:47 EST news239370278 Cheers! A new research report appearing in the October 2011 issue of The FASEB Journal shows that resveratrol, the "healthy" ingredient in red wine, stops breast cancer cells from growing by blocking the growth effects of estrogen. This discovery, made by a team of American and Italian scientists, suggests for the first time that resveratrol is able to counteract the malignant progression since it inhibits the proliferation of hormone resistant breast cancer cells. This has important implications for the treatment of women with breast cancer whose tumors eventually develop resistance to hormonal therapy. http://medicalxpress.com/news/2011-09-red-wine-ingredient-resveratrol-breast.html Cancer Thu, 29 Sep 2011 10:17:17 EST news236510225 Researchers in the Faculty of Medicine & Dentistry at the University of Alberta have discovered that resveratrol, a powerful antioxidant found in common foods, prevents a syndrome in some offspring that could lead to later health issues such as diabetes. http://medicalxpress.com/news/2011-09-powerful-antioxidant-resveratrol-metabolic-syndrome.html Medical research Fri, 02 Sep 2011 15:16:45 EST news234195389 For many years doctors believed the estrogen women consumed in the form of oral contraceptives and hormone replacement therapy (HRT) pills was good for their patients' hearts. Recent studies however have shown that long-term exposure to estrogen can be a danger to women as it has been associated with high blood pressure, a key link to heart- and brain-attacks (strokes). Although the process by which estrogen induces high blood pressure in females is unclear, Michigan State University (MSU) researchers have found that long-term estrogen exposure generates excessive levels of a compound, superoxide, which causes stress in the body. The build-up of this compound occurs in an area of the brain that is crucial to regulating blood pressure, suggesting that chronic estrogen induces a build up of superoxide that in turn causes blood pressure to increase. The study also found that the anti-oxidant resveratrol reverses the increase in both superoxide and blood pressure. http://medicalxpress.com/news/2011-05-link-chronic-estrogen-exposure-high.html Medical research Thu, 26 May 2011 11:27:38 EST news225628037