http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A new conjugate vaccine is highly effective (93%) at preventing invasive pneumococcal disease (IPD; meningitis, sepsis, bacteremic pneumonia, and other blood-borne infections) in infants younger than 2 years who are the most vulnerable to infection, according to new research published Online First in The Lancet. The nationwide study is the first to confirm the effectiveness of the three-dose (2+1) schedule that is already used in many national programs. http://medicalxpress.com/news/2012-11-european-randomized-trial-pneumococcal-vaccine.html Diseases, Conditions, Syndromes Thu, 15 Nov 2012 18:30:01 EST news272219574 Dengue has spread in Portugal's Madeira archipelago since it appeared last week and there are now 18 confirmed cases, health officials said Wednesday. http://medicalxpress.com/news/2012-10-dengue-madeira-archipelago.html Diseases, Conditions, Syndromes Wed, 10 Oct 2012 11:32:49 EST news269087559 The challenge of treating patients with genetic disorders in which a single mutated gene is simply too large to be replaced using traditional gene therapy techniques may soon be a thing of the past. A Nationwide Children's Hospital study describes a new gene therapy approach capable of delivering full-length versions of large genes and improving skeletal muscle function. The strategy may hold new hope for treating dysferlinopathies and other muscular dystrophies. http://medicalxpress.com/news/2012-07-gene-strategy-limb-girdle-muscular.html Genetics Mon, 09 Jul 2012 03:59:42 EST news261025052 (Phys.org) -- A group of scientists in Singapore and the UK have isolated a human antibody capable of effectively neutralizing the mosquito-borne dengue virus. Dengue fever is currently incurable and infects an estimated 100,000 people a year, mostly in the tropics. The only treatment is alleviating the symptoms, which can include intense joint and muscle pain, nausea, vomiting, high fever, and death in severe cases. http://medicalxpress.com/news/2012-06-human-antibody-dengue-virus-isolated.html Diseases, Conditions, Syndromes Fri, 22 Jun 2012 05:40:01 EST news259560458 Researchers at the Johns Hopkins Bloomberg School of Public Health have found evidence of a role for neighborhood immunity in determining risk of dengue infection. While it is established that immunity can be an important factor in the large-scale distribution of disease, this study demonstrates that local variation at spatial scales of just a few hundred meters can significantly alter the risk of infection, even in a highly mobile and dense urban population with significant immunity. The study is published in May 28 edition of the journal PNAS. http://medicalxpress.com/news/2012-05-disease-transmission.html Diseases, Conditions, Syndromes Mon, 28 May 2012 15:00:24 EST news257415663 A clinical trial testing a candidate HIV vaccine known as the STEP study was halted in September 2007 after interim analysis indicated that the vaccine did not work. http://medicalxpress.com/news/2011-12-potential-obstacle-hiv-vaccine.html HIV & AIDS Tue, 27 Dec 2011 12:00:03 EST news244196479