http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Injected with a fluorescent protein to make them glow bright red, laboratory mice are helping Czech scientists better understand the causes behind intestinal cancers and skin diseases while leaving the rodents unscathed. http://medicalxpress.com/news/2013-03-red-mice-czechs-bowel-cancer.html Medical research Wed, 13 Mar 2013 11:11:47 EST news282391900 Fresh insights into the protective seal that surrounds the DNA of our cells could help develop treatments for inherited muscle, brain, bone and skin disorders. http://medicalxpress.com/news/2013-02-cell-discovery-key-inherited-diseases.html Medical research Tue, 26 Feb 2013 11:39:36 EST news281101152 (Medical Xpress)—Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the National Institutes of Health, and the University of Oxford, U.K., have shed light on a long-standing enigma about the structure of a protein related to the Hepatitis B virus. Their findings, reported in Structure, could lead to new therapeutic strategies for chronic liver disease. http://medicalxpress.com/news/2013-01-scientists-mystery-hepatitis-virus-discovery.html Medical research Wed, 09 Jan 2013 06:29:17 EST news276935350 Hair care and maintenance issues are primary factors that deter African-American women from exercising, a major health concern for a group that has the highest rates of overweight or obesity in the country. http://medicalxpress.com/news/2012-12-hair-issues-contribute-barriers-african-american.html Health Mon, 17 Dec 2012 16:00:01 EST news274959349 Melanoma is so dangerous because it tends to metastasize early on. New treatment approaches utilize, among other things, the ability of the immune defense to search out and destroy malignant cells. Yet this strategy is often only temporarily effective. A research team under the direction of Bonn University has discovered why this is the case: In the inflammatory reaction caused by the treatment, the tumor cells temporarily alter their external characteristics and thus become invisible to defense cells. This knowledge forms an important foundation for the improvement of combination therapies. http://medicalxpress.com/news/2012-10-melanoma-cells-circumvent-immune.html Cancer Wed, 10 Oct 2012 13:00:06 EST news269091890 In the July 6 issue of Cell Stem Cell, researchers at the University of California, San Diego School of Medicine describe how human epidermal progenitor cells and stem cells control transcription factors to avoid premature differentiation, preserving their ability to produce new skin cells throughout life. http://medicalxpress.com/news/2012-07-key-proteins-self-renewing-skin.html Medical research Thu, 05 Jul 2012 13:38:48 EST news260714319 (Medical Xpress) -- A research team at Karolinska Institutet has succeeded in describing the structure and function of the outermost layer of the skin - the stratum corneum - at a molecular level. This opens the way not only for the large-scale delivery of drugs via the skin, but also for a deeper understanding of skin diseases. http://medicalxpress.com/news/2012-04-breakthrough-drugs-skin.html Medical research Thu, 26 Apr 2012 08:47:57 EST news254648865 A new study shows that Kineret (anakinra), a medication approved for the treatment of rheumatoid arthritis, is effective in stopping the progression of organ damage in people with neonatal-onset multisystem inflammatory disease (NOMID). This rare and debilitating genetic disorder causes persistent inflammation and ongoing tissue damage. The research was performed by scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the National Institutes of Health. http://medicalxpress.com/news/2012-02-drug-halts-inflammatory-genetic-disorder.html Inflammatory disorders Fri, 10 Feb 2012 12:55:00 EST news248100889 New research presented at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) found that more than 4.5 million Americans are living with a total knee replacement (TKR), as the number of TKR surgeries has more than doubled over the past decade, with the sharpest rise among younger patients. Osteoarthritis continues to be the primary reason for TKR. http://medicalxpress.com/news/2012-02-million-americans-total-knee.html Arthritis & Rheumatism Fri, 10 Feb 2012 05:22:22 EST news248073735 A new study unravels key signals that regulate protective and sometimes pathological inflammation of the skin. The research, published online on January 26th in the journal Immunity by Cell Press, identifies a "gatekeeper" that, when lost, can cause inflammatory skin disease in the absence of injury or infection. The findings may eventually lead to new treatment strategies for the more than 10% of people in the western world that suffer from inflammatory skin diseases. http://medicalxpress.com/news/2012-01-gatekeeper-skin-inflammation.html Medical research Thu, 26 Jan 2012 12:35:13 EST news246803700 A new study, funded by a grant from the National Institute for Arthritis and Musculoskeletal and Skin Diseases (NIAMS), found that two in five adults (42%) with rheumatoid arthritis (RA) were inactive. Taking measures to motivate RA patients to increase their physical activity will improve public health according to the findings now available in Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR). http://medicalxpress.com/news/2012-01-adults-rheumatoid-arthritis-physically-inactive.html Arthritis & Rheumatism Thu, 26 Jan 2012 04:16:19 EST news246773769 Northwestern Medicine researchers have received two five-year grants totaling $953,000 from the National Institutes of Health's (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases to study scleroderma, an autoimmune disease for which there currently is no cure. The grants will enable researchers at Northwestern to identify biomarkers for the disease, and are the first step in developing a national resource for investigators studying scleroderma. http://medicalxpress.com/news/2011-12-northwestern-explore-personalized-medicine-scleroderma.html Diseases, Conditions, Syndromes Fri, 02 Dec 2011 02:30:01 EST news242014639 (Medical Xpress) -- Scientists have taken major steps forward to curing severe skin blistering diseases like epidermolysis bullosa which ruin thousands of lives in the UK every year. http://medicalxpress.com/news/2011-11-scientists-defective-genes-skin-blistering.html Medical research Mon, 07 Nov 2011 09:14:07 EST news239879618 An international collaboration of scientists, including researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health, has identified a genetic mutation that causes a rare childhood disease characterized predominantly by inflammation and fat loss. The research suggests that the disorder, named chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE), actually represents a spectrum of diseases that have been described in the literature under a variety of names. More importantly, since no effective treatment for this disease currently exists, the findings may have uncovered a possible target for future treatments. http://medicalxpress.com/news/2011-10-scientists-link-spectrum-childhood-diseases.html Diseases, Conditions, Syndromes Mon, 31 Oct 2011 11:33:22 EST news239279590 (Medical Xpress) -- An immune cell involved in initiating the symptoms of an allergic skin reaction may play an equally, or perhaps more important, role in suppressing the reaction once it becomes chronic. This finding in mice could have future implications for the treatment of atopic dermatitis, a chronic inflammatory skin disease that affects an estimated 10 to 20 percent of infants and young children. The research is by investigators at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the National Institutes of Health. http://medicalxpress.com/news/2011-10-immune-cell-dual-role-allergic.html Medical research Tue, 18 Oct 2011 10:10:25 EST news238151413 A novel technique that enables scientists to measure and document tumor-inducing changes in DNA is providing new insight into the earliest events involved in the formation of leukemias, lymphomas and sarcomas, and could potentially lead to the discovery of ways to stop those events. http://medicalxpress.com/news/2011-09-technique-events-tumor.html Cancer Thu, 29 Sep 2011 13:27:18 EST news236521626 An analysis of several studies shows that people with Parkinson's disease have a significantly higher risk of melanoma, the most dangerous type of skin cancer and the leading cause of death from skin diseases. The research is published in the June 7, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology. http://medicalxpress.com/news/2011-06-people-parkinson-disease-melanoma-dangerous.html Diseases, Conditions, Syndromes Mon, 06 Jun 2011 16:22:13 EST news226596099 A preliminary study conducted by a team at the National Institutes of Health has identified a promising new treatment in children for the most common form of a rare disorder. The syndrome is called periodic fever associated with aphthous stomatitis, pharyngitis and cervical adenitis -- or PFAPA -- and is characterized by monthly flare-ups of fever, accompanied by sore throat, swollen glands and mouth lesions. http://medicalxpress.com/news/2011-04-treatment-common-recurrent-fever-children.html Medical research Fri, 08 Apr 2011 17:09:48 EST news221501369