http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Short-term use of antidepressants, combined with stress and a high-fat diet, is associated with long-term increases in body weight, a new animal study finds. The results were presented Sunday at The Endocrine Society's 95th Annual Meeting in San Francisco. http://medicalxpress.com/news/2013-06-short-term-antidepressant-stress-high-fat-diet.html Overweight and Obesity Mon, 17 Jun 2013 11:45:38 EST news290688328 Imagine a hospital where patient data from numerous sources is made accessible to ward physicians with the help of hyperlinks and intelligent indexing. Imagine a healthcare system that hands its patients – not an envelope or a CD-ROM – but an integrated dataset that allows them to truly understand their illness, and even use the Internet to obtain additional information. Imagine a radiologist who uses semantic technologies to navigate smoothly through the myriad imaging data. Welcome to the future of semantic technologies in health information retrieval. http://medicalxpress.com/news/2013-04-knowledge-pure.html Other Mon, 15 Apr 2013 09:10:01 EST news285233448 The spleen is rarely noticed, until it is missing. In children born without this organ, that doesn't happen until they become sick with life-threatening bacterial infections. An international team of researchers led by scientists from Rockefeller's St. Giles Laboratory of Human Genetics and Infectious Diseases has now identified the defective gene responsible for this rare disorder. The findings, reported today in Science Express, may lead to new diagnostic tests and raises new questions about the role of this gene in the body's protein-making machinery. http://medicalxpress.com/news/2013-04-scientists-gene-mutation-children-born.html Genetics Thu, 11 Apr 2013 14:00:08 EST news284907208 (Medical Xpress)—For an immune response to get underway, an invading microbe must first be halted in the spleen, and then digested by immune cells known as 'dendritic cells', which guard specific portals. Australian scientists have now shown how these gatekeepers position themselves to undertake their task. http://medicalxpress.com/news/2013-03-immune-positions-gatekeepers.html Immunology Tue, 19 Mar 2013 08:29:23 EST news282900532 Nearly every cell in the human body carries a copy of the full human genome. So how is it that the cells that detect light in the human eye are so different from those of, say, the beating heart or the spleen? http://medicalxpress.com/news/2013-02-epigenetic-marker-5hmc-door-role.html Genetics Mon, 04 Feb 2013 16:08:27 EST news279216417 A simple, inexpensive blood test performed on trauma patients upon admission can help doctors easily identify patients at greatest risk of death, according to a new study by researchers at Intermountain Medical Center in Salt Lake City. http://medicalxpress.com/news/2013-01-simple-blood-trauma-patients-greatest.html Health Fri, 18 Jan 2013 00:20:01 EST news277661804 An excessive response of the immune system to malarial infection can lead to serious complications, such as cerebral malaria. While the mechanism causing the onset of cerebral malaria is unclear, immunologists think that contributing factors include cells of the immune system and the inflammation that they cause. Laurent Renia and co-workers at the A*STAR Singapore Immunology Network and collaborators from Nanyang Technological University, Singapore, have now singled out one subtype of immune cells that is key to the onset of this often fatal disease. http://medicalxpress.com/news/2013-01-cerebral-malaria-potential-therapeutic.html Immunology Wed, 16 Jan 2013 08:34:57 EST news277547686 Scientists—including a geneticist at The University of Western Australia—are a step closer to developing a vaccine against a fatally infectious parasite carried in the bite of sandflies. http://medicalxpress.com/news/2013-01-genetics-discovery-black-fever.html Genetics Tue, 08 Jan 2013 05:58:17 EST news276847089 Using mesenchymal stromal cells derived from adipose (fat) tissues, genetically modified to express a bioluminescent marker, researchers in Italy have tracked cells after transplantation. The cells were followed from their injection into the spleen of mice modeling liver disease, to their characterization as "hepatic precursors," and to their subsequent migration through the spleen before engrafting at regenerating sites in the liver by bioluminescent imaging. http://medicalxpress.com/news/2012-12-transplanted-genetically-modified-adipose-cells-potential.html Medical research Thu, 20 Dec 2012 16:50:01 EST news275244596 Researchers have demonstrated that combination therapy with PU-H71 and ruxolitinib increases the durability and effectiveness of a treatment that had previously shown limited utility for patients with myelofibrosis. http://medicalxpress.com/news/2012-12-combination-therapy-jak2-hsp90-inhibitors.html Cancer Sun, 09 Dec 2012 12:00:03 EST news274274558 Researchers in New Zealand are inching closer to the development of the first effective oral vaccine to protect against tuberculosis - a disease which still kills more people worldwide than any other bacterial disease. http://medicalxpress.com/news/2012-09-otago-collaboration-oral-tb-vaccine.html Diseases, Conditions, Syndromes Wed, 26 Sep 2012 09:48:50 EST news267871641 Novartis AG and Incyte Corp. said Tuesday that European Union regulators approved their blood cancer drug Jakavi. http://medicalxpress.com/news/2012-09-eu-novartis-incyte-blood-cancer-drug.html Medications Tue, 04 Sep 2012 08:10:37 EST news265965018 It is likely that the protein is also highly significant for other inflammatory diseases. http://medicalxpress.com/news/2012-08-immune-protein-pancreatitis.html Immunology Fri, 31 Aug 2012 11:09:01 EST news265630132 A study by a Baylor College of Medicine physician-researcher has shed light on the most effective treatment for adults with Langerhans cell histiocytosis (LCH) in bones. LCH is a disease that can affect the skin, mouth, ears, bones, brain, gastrointestinal system, liver, spleen, or bone marrow. http://medicalxpress.com/news/2012-08-treatment-adults-langerhans-cell-histiocytosis.html Diseases, Conditions, Syndromes Wed, 15 Aug 2012 17:00:06 EST news264262793 The first biologically tissue-engineered vein grown from a patient's own stem cells has been successfully transplanted into a 10-year-old girl with portal vein obstruction, dramatically enhancing her quality of life. These pioneering results, published online first in the Lancet, could offer a potential new way for patients lacking healthy veins to undergo dialysis or heart bypass surgery without the problems of synthetic grafts (that are prone to clots and blockages) or the need for lifelong immunosuppressive drugs. http://medicalxpress.com/news/2012-06-successful-transplantation-tissue-engineered-vein-child.html Immunology Wed, 13 Jun 2012 18:30:01 EST news258811550 Researchers at Weill Cornell Medical College and Rockefeller University have identified the first gene to be linked to a rare condition in which babies are born without a spleen, putting those children at risk of dying from infections they cannot defend themselves against. The gene, Nkx2.5, was shown to regulate genesis of the spleen during early development in mice. http://medicalxpress.com/news/2012-05-gene-linked-spleen-newborns.html Genetics Thu, 03 May 2012 15:00:03 EST news255273938 Music has a fundamental affect on humans. It can reduce stress, enhance relaxation, provide a distraction from pain, and improve the results of clinical therapy. New research published in BioMed Central's open access journal Journal of Cardiothoracic Surgery demonstrates that music can reduce rejection of heart transplants in mice by influencing the immune system. http://medicalxpress.com/news/2012-03-music-heart-transplant.html Cardiology Thu, 22 Mar 2012 20:00:02 EST news251654476 Cells that die naturally generate a lot of internal debris that can trigger the immune system to attack the body, leading to diseases such as lupus. http://medicalxpress.com/news/2012-02-natural-method-cellular-debris-lupus.html Immunology Fri, 24 Feb 2012 04:40:01 EST news249280333 For the first time, it has been discovered that neutrophils exist in the spleen without there being an infection. This important finding made by the research group on the Biology of B Cells of IMIM (Hospital del Mar Research Institute) in collaboration with researchers from Mount Sinai in New York, has also made it possible to determine that these neutrophils have an immunoregulating role. http://medicalxpress.com/news/2011-12-neutrophils-spleen.html Medical research Sun, 25 Dec 2011 13:00:05 EST news244014592 An analysis of lung and spleen tissue from patients who died of sepsis revealed certain biochemical, cellular and histological findings that were consistent with immunosuppression, according to a study in the December 21 issue of JAMA. http://medicalxpress.com/news/2011-12-severe-sepsis-impairment-immune.html Immunology Tue, 20 Dec 2011 16:01:57 EST news243619303 Groundbreaking research from the Queensland Institute of Medical Research is set to pave the way for the development of new malaria drugs and vaccines. http://medicalxpress.com/news/2011-11-breakthrough-malaria-body-immune-cells.html Medical research Fri, 25 Nov 2011 11:20:01 EST news241440950 The first drug to treat a rare disorder that causes red blood cells to build up inside bone marrow was cleared Wednesday by the Food and Drug Administration http://medicalxpress.com/news/2011-11-fda-drug-bone-marrow-disorder.html Medications Wed, 16 Nov 2011 12:59:10 EST news240670722 Scientists have identified a surprising new role for a new type of T cell in the immune system: some of them can be activated by nerves to make a neurotransmitter (acetylcholine) that blocks inflammation. The discovery of these T cells is novel and suggests that it may be possible to treat inflammation and autoimmune diseases by targeting the nerves and the T cells. The study was published this week in Science. http://medicalxpress.com/news/2011-09-cells-brain-chemicals-treatments-inflammation.html Medical research Fri, 16 Sep 2011 11:00:30 EST news235389535