http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. In a randomized phase III clinical trial conducted by the Radiation Therapy Oncology Group (RTOG), high-dose (HD), compared with standard-dose (SD), radiotherapy (RT) with concurrent chemotherapy (CT) did not improve overall survival of patients with stage III non-small-cell lung cancer (NSCLC). http://medicalxpress.com/news/2013-05-higher-dose-rt-results-inferior-survival.html Cancer Wed, 29 May 2013 15:03:09 EST news289058583 The drug aclidinium bromide (trade names Eklira, Bretaris) has been approved since October 2012 for widening the narrowed airways of adults with chronic-obstructive pulmonary disease (COPD). The German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined the added benefit of the drug pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG). No proof of an added benefit of aclidinium bromide compared with the appropriate comparator therapy (ACT) can be inferred from the data in the drug manufacturer's dossier. http://medicalxpress.com/news/2013-01-added-benefit-aclidinium-bromide-proven.html Medications Wed, 30 Jan 2013 09:38:03 EST news278760982 (HealthDay)—For patients with treatment-naive Hodgkin's lymphoma (HL) staged using [18F]fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT), routine bone marrow biopsy (BMB) has little or no therapeutic consequence, according to research published online Nov. 13 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-11-bone-marrow-biopsy-petct-staging.html Cancer Thu, 15 Nov 2012 04:50:01 EST news272174738 Colon cancer survivors whose diet is heavy in complex sugars and carbohydrate-rich foods are far more likely to have a recurrence of the disease than are patients who eat a better balance of foods, a new study by Dana-Farber Cancer Institute researchers indicates. http://medicalxpress.com/news/2012-11-starchy-high-carbohydrate-diet-recurrence.html Cancer Wed, 07 Nov 2012 16:00:02 EST news271517732 A study of survival data for Stage III, non-small cell lung cancer (NSCLC) patients at the University of Maryland's Greenebaum Cancer Center in Baltimore indicates that marital status and race can significantly impact patient survival rates, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology. This symposium is sponsored by the American Society of Clinical Oncology (ASCO), the American Society for Radiation Oncology (ASTRO), the International Association for the Study of Lung Cancer (IASLC), and The University of Chicago. http://medicalxpress.com/news/2012-09-marital-status-survival-significantly-stage.html Cancer Thu, 06 Sep 2012 15:07:01 EST news266162815 Stage III non-small cell lung cancer (NSCLC) patients treated with surgery and/or radiation therapy have a significantly reduced risk of developing brain metastases if they also receive prophylactic cranial irradiation (PCI); however, this study did not show an improvement in overall survival with PCI, according to research presented at the 2012 Chicago Multidisciplinary Symposium in Thoracic Oncology. This symposium is sponsored by the American Society of Clinical Oncology (ASCO), the American Society for Radiation Oncology (ASTRO), the International Association for the Study of Lung Cancer (IASLC) and The University of Chicago. http://medicalxpress.com/news/2012-09-brain-lung-cancer-treatment.html Cancer Thu, 06 Sep 2012 13:47:21 EST news266158033 A new epidemiological study led by UC Davis researchers reveals significant racial disparities in the use of non-surgical larynx-preservation therapy for locally advanced laryngeal cancer. http://medicalxpress.com/news/2012-07-reveals-racial-disparities-voice-box-preserving.html Cancer Mon, 16 Jul 2012 16:00:07 EST news261672860 Researchers and doctors at the North Shore-LIJ Health System and the Feinstein Institute for Medical Research have discovered that blood can help determine the best treatment plan for patients with ovarian cancer. More specifically, a genetic marker embedded in deoxyribonucleic acid (DNA), called microRNA, indicates if a patient with ovarian cancer has a benign or cancerous tumor, and that she will benefit from chemotherapy after surgery on the tumor. This data will be presented at the American Association for Cancer Research (AACR) Annual Meeting to be held from Saturday through Wednesday (March 31- April 4) in Chicago, IL. http://medicalxpress.com/news/2012-04-dna-marker-ovarian-cancer-treatment.html Cancer Tue, 03 Apr 2012 16:09:14 EST news252688146 Adding the drug cetuximab to a regimen of drugs used for the treatment of patients following surgery for stage III colon cancer did not result in improved disease-free survival, according to a study in the April 4 issue of JAMA. http://medicalxpress.com/news/2012-04-adding-drug-chemotherapy-colon-cancer.html Cancer Tue, 03 Apr 2012 16:02:50 EST news252687759 (HealthDay) -- Nearly 40 percent of patients undergoing adjuvant chemotherapy for stage III colon cancer experience financial hardship, even if they have health insurance coverage, according to research published online March 12 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-03-financial-hardship-common-colon-cancer.html Cancer Tue, 13 Mar 2012 15:50:01 EST news250867375 (HealthDay) -- The prevalence of older people with cancer using complementary medications as they start a chemotherapy regimen is 17 percent, and is associated with less advanced disease and higher functional status, according to a study published online Feb. 22 in Cancer. http://medicalxpress.com/news/2012-03-complementary-meds-percent-elderly-cancer.html Cancer Fri, 02 Mar 2012 12:42:01 EST news249914514 Based on a study of nearly 2,000 breast cancer patients, researchers at the Swedish Cancer Institute in Seattle say that, in women between the ages of 40 and 49, breast cancers detected by mammography have a better prognosis. The study appears in the March issue of Radiology. http://medicalxpress.com/news/2012-02-mammography-detected-breast-cancer-year-olds.html Cancer Wed, 22 Feb 2012 05:30:03 EST news249109380 Stage III colon cancer patients in the general population who receive adjuvant treatment for the disease have an improved rate of survival when oxaliplatin is added to 5-fluorouracil (5FU), according to a study published Jan. 20 in the Journal of the National Cancer Institute. http://medicalxpress.com/news/2012-01-oxaliplatin-colon-cancer-patient-survival.html Cancer Fri, 20 Jan 2012 17:53:32 EST news246304402 Targeted drugs, which block or disrupt particular molecules involved in the growth of tumors, have been shown to be effective treatments against many types of cancer. A new phase 3 clinical trial conducted by the Gynecologic Oncology Group (GOG) showed that a targeted therapy called bevacizumab (Avastin) effectively delayed the progression of advanced ovarian cancer. Patients with newly diagnosed advanced ovarian cancer now typically undergo surgery and chemotherapy, but the new research suggests an additional avenue of treatment. The results of the trial appear in the December 29 issue of the New England Journal of Medicine. http://medicalxpress.com/news/2011-12-therapy-progression-free-survival-patients-advanced.html Cancer Wed, 28 Dec 2011 17:00:01 EST news244292529 The presence of circulating tumor cells in the blood appears to have no relationship to survival in women who have just been diagnosed with inflammatory breast cancer, according to new research from Fox Chase Cancer Center. However, the research shows that these stray tumor cells may signal that the disease has spread to other parts of the body, even before imaging reveals any metastases. The results will be presented on Friday, December 9 at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium. http://medicalxpress.com/news/2011-12-circulating-tumor-cells-linked-survival.html Inflammatory disorders Fri, 09 Dec 2011 08:43:26 EST news242642333 A higher dose of radiation (74 Gy) does not improve overall survival for non-small cell lung cancer that has spread to the lymph nodes, compared to the standard radiation dose (60 Gy), according to an interim analysis of a late-breaking randomized study presented at the plenary session, October 3, 2011, at the 53rdAnnual Meeting of the American Society for Radiation Oncology (ASTRO). http://medicalxpress.com/news/2011-10-higher-dose-lung-cancer-patients.html Cancer Mon, 03 Oct 2011 12:36:17 EST news236864165 Nearly 50,000 Americans are diagnosed each year with stage III or locally advanced NSCLC, for which surgery is usually not a viable treatment option. Optimizing nonsurgical treatment strategies for these patients is an ongoing research endeavor. In an article published online September 8, 2011 in the Journal of the National Cancer Institute, RTOG researchers report that treating patients with concurrent chemotherapy and radiation therapy significantly increased five‑year survival rates compared with treating patients with radiation therapy upon completion of chemotherapy treatment. http://medicalxpress.com/news/2011-09-concurrent-chemo-therepy-long-term-survival.html Cancer Thu, 08 Sep 2011 17:14:55 EST news234720881 It's not how old but how frail patients are that can predict how well they will fare after a melanoma diagnosis. In fact, young patients in poor health may have worse outcomes than older patients in good shape. http://medicalxpress.com/news/2011-08-patients-underlying-health-linked-worse.html Cancer Tue, 30 Aug 2011 11:26:56 EST news233922395