http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Scientists at the Arkansas Children's Nutrition Center, a U.S. Department of Agriculture Agricultural Research Service Human Nutrition Research Center at the University of Arkansas for Medical Sciences, led by Dr. Martin Ronis have determined that dietary substitution of saturated fats enriched in medium chain triglycerides (MCT) for polyunsaturated fat prevents the development of nonalcoholic fatty liver disease (NAFLD). NAFLD occurs in patients with obesity and type II diabetes and is being seen at younger ages in association with the obesity epidemic. NAFLD is characterized by excessive accumulation of fat in the liver. In a proportion of NAFLD cases, liver pathology progresses to hepatitis, fibrosis and liver cancer. http://medicalxpress.com/news/2013-04-dietary-medium-chain-triglycerides-nonalcoholic.html Diseases, Conditions, Syndromes Wed, 24 Apr 2013 15:46:46 EST news286037198 A potential new way to fight obesity-related illness has been uncovered, thanks to serendipitous research led by investigators at the Case Western Reserve University School of Medicine. http://medicalxpress.com/news/2013-04-vitamin-potential-weapon-obesity.html Overweight and Obesity Tue, 23 Apr 2013 13:34:49 EST news285942879 (Medical Xpress)—Research at Oregon State University has found that one particular omega-3 fatty acid has a powerful effect in preventing liver inflammation and fibrosis – common problems that are steadily rising along with the number of Americans who are overweight. http://medicalxpress.com/news/2013-02-omega-oils-liver-disease.html Diseases, Conditions, Syndromes Tue, 05 Feb 2013 12:47:46 EST news279290860 A new study from the Virginia Commonwealth University School of Medicine has identified molecular changes responsible for abnormal cholesterol production and metabolism in the livers of patients with a common liver condition, and these changes may explain the severity of a patient's liver disease and risks to their heart health. http://medicalxpress.com/news/2012-06-cholesterol-metabolic-pathways.html Medical research Thu, 07 Jun 2012 17:01:20 EST news258307274 EASL today announced the publication of a new clinical practice guideline (CPG) in the area of Alcoholic Liver Disease (ALD), bringing the number of CPGs published to date to eight. http://medicalxpress.com/news/2012-04-clinical-guidelines-alcoholic-liver-disease.html Diseases, Conditions, Syndromes Thu, 19 Apr 2012 07:01:38 EST news254037664 New research found the genetic variant Patatin-like phospholipase domain containing protein-3 (PNPLA3) acting in conjunction with the glucokinase regulatory protein (GCKR) is associated with increased susceptibility to fatty liver disease in obese children. The study, published in the March issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, determined the PNPLA3 and GCKR single nucleotide polymorphisms (SNPs) were responsible for up to 39% of the hepatic fat content in this pediatric population. http://medicalxpress.com/news/2012-03-genetic-variants-linked-fatty-liver.html Genetics Fri, 23 Mar 2012 10:22:58 EST news251716965 Caffeine consumption has long been associated with decreased risk of liver disease and reduced fibrosis in patients with chronic liver disease. Now, newly published research confirms that coffee caffeine consumption reduces the risk of advanced fibrosis in those with nonalcoholic fatty liver disease (NAFLD). Findings published in the February issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, show that increased coffee intake, specifically among patients with nonalcoholic steatohepatitis (NASH), decreases risk of hepatic fibrosis. http://medicalxpress.com/news/2012-02-coffee-consumption-fibrosis-fatty-liver.html Diseases, Conditions, Syndromes Thu, 02 Feb 2012 11:35:24 EST news247404915 With the launch of a new clinical trial supported by the National Institutes of Health, researchers are working to determine whether treating children diagnosed with the most severe form of fatty liver disease with a drug called cysteamine will help improve the liver. http://medicalxpress.com/news/2012-01-nih-treatment-fatty-liver-disease.html Diseases, Conditions, Syndromes Thu, 12 Jan 2012 06:42:03 EST news245572907 Nonalcoholic steatohepatitis (NASH) occurs when fat builds up in the liver. This accumulation of fat damages the liver and leads to cirrhosis. NASH is rapidly increasing in the U.S. mainly related to the epidemics of obesity and diabetes. As a result, the proportion of liver transplantations performed for NASH cirrhosis rose dramatically from roughly 1% in 1997-2003 to more than 7% in 2010. However, according to new research published in Liver Transplantation, a peer-reviewed journal of the American Association for the Study of Liver Diseases, post-transplantation survival for NASH patients is excellent, with one-year survival rates near 88%. http://medicalxpress.com/news/2011-12-obesity-diabetes-epidemics-spur-nonalcoholic.html Diseases, Conditions, Syndromes Wed, 14 Dec 2011 10:22:30 EST news243080536