http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Black women with breast cancer were found to be three times more likely than their white counterparts to delay treatment for more than 90 days—a time delay associated with increased deaths from the disease, according to a new study led by researchers at Georgetown Lombardi Comprehensive Cancer Center. http://medicalxpress.com/news/2013-05-breast-cancer-treatment-varies-patient-doctor.html Cancer Tue, 07 May 2013 12:37:05 EST news287149018 As part of a multicenter clinical trial, researchers at University of California, San Diego School of Medicine are evaluating Pexa-Vec (JX-594) to slow the progression of hepatocellular carcinoma (HCC) or liver cancer. Pexa-Vec is a genetically engineered virus that is used in the smallpox vaccine. http://medicalxpress.com/news/2013-04-small-pox-liver-cancer.html Cancer Wed, 10 Apr 2013 10:58:47 EST news284810321 Two novel radiolabeled small molecules targeting prostate-specific membrane antigen (PSMA) have excellent potential for further development as diagnostic and therapeutic radiopharmaceuticals, according to research published this month in The Journal of Nuclear Medicine. The imaging agents—123I-MIP-1072 and 123I-MIP-1095—were shown to have a high sensitivity of lesion detection in bone, soft tissue and the prostate gland with minimal retention in non-target tissue. http://medicalxpress.com/news/2013-03-small-molecules-visualize-prostate-cancer.html Cancer Tue, 05 Mar 2013 11:05:12 EST news281703906 The median age of patients diagnosed with advanced non–small-cell lung cancer (NSCLC) has steadily increased over the recent years and is presently 70 years. Despite this, the elderly are significantly underrepresented in clinical trials. A recent study published in the March 2013 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, investigated the degree to which exclusion or underrepresentation of elderly occurs in practice-changing clinical trials in advanced NSCLC. Researchers conclude that greater representation of elderly patients in phase III trials is required to better define evidence-based paradigms in the increasingly elderly NSCLC population. http://medicalxpress.com/news/2013-02-greater-representation-elderly-patients-phase.html Cancer Fri, 22 Feb 2013 09:33:41 EST news280748016 Local therapy is not commonly utilized in metastatic lung cancer. Researchers at Memorial Sloan-Kettering Cancer Center investigated the efficacy of local therapy with continued EGFR TKI therapy specifically in patients with acquired resistance to EGFR TKIs. A recent study published in the March 2013 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, found that EGFR- mutant lung cancers with acquired resistance to EGFR TKI therapy are amenable to local therapy to treat oligometastatic disease when used in conjunction with continued EGFR inhibition. http://medicalxpress.com/news/2013-02-local-therapy-treatment-egfr-tki.html Cancer Fri, 22 Feb 2013 09:33:30 EST news280748004 Axillary lymph node dissection is done in conjunction with lumpectomy or mastectomy to determine if breast cancer has spread to the adjoining lymph nodes. The conventional surgical approach leaves a surgical scar that is unattractive and can restrict range of motion in the shoulder joint. Also, squeezing and pulling the tumor during the breast operation can stimulate tumor cell metastases. A new study in the December issue of Mayo Clinic Proceedings reports that an endoscopic technique, mastoscopic axillary lymph node dissection (MALND), can reduce these complications. http://medicalxpress.com/news/2012-11-minimally-invasive-lymph-node-breast.html Cancer Fri, 09 Nov 2012 00:00:01 EST news271614186 Use of tumor necrosis factor (TNF) inhibitors for treatment of psoriasis is associated with a significantly reduced risk for heart attack (myocardial infarction) compared to other forms of treatment, according to a report published Online First by Archives of Dermatology. http://medicalxpress.com/news/2012-08-heart-psoriasis-treatments.html Diseases, Conditions, Syndromes Mon, 20 Aug 2012 16:00:07 EST news264692845 (HealthDay) -- Treating patients with surgically unresectable metastatic colon cancer and an asymptomatic intact primary tumor with bevacizumab and infusional fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) chemotherapy is a viable and safe option, according to research published online Aug. 6 in the Journal of Clinical Oncology. http://medicalxpress.com/news/2012-08-nonoperative-approach-feasible-advanced-colon.html Cancer Thu, 09 Aug 2012 11:42:53 EST news263731366 (HealthDay) -- About 20 percent of patients diagnosed with stage IV metastatic solid tumors do not receive anticancer treatment, according to a study published online June 15 in Cancer. http://medicalxpress.com/news/2012-06-therapy-percent-stage-iv-solid.html Cancer Sat, 23 Jun 2012 06:58:31 EST news259653498 An experimental drug targeting a common mutation in melanoma successfully shrank tumors that spread to the brain in nine out of 10 patients in part of an international phase I clinical trial report in the May 18 issue of The Lancet. http://medicalxpress.com/news/2012-05-dabrafenib-melanoma-brain-metastases-phase.html Cancer Thu, 17 May 2012 18:30:01 EST news256493208 Breast cancer in young women is linked to age-related biological processes, a new study shows. Because it is a biologically unique disease, it calls for tailor-made management strategies, researchers reported at the IMPAKT Breast Cancer Conference in Brussels, Belgium from 3 to 5 May. The findings, presented in the journal Annals of Oncology, could impact potential treatment methods, especially because breast cancer in young women is often aggressive and diagnosed at an advanced stage. The prognosis for young patients is not good. http://medicalxpress.com/news/2012-05-scientists-link-biological-young-breast.html Cancer Mon, 07 May 2012 06:40:53 EST news255591644 (HealthDay) -- The effectiveness of therapies for psoriasis is variable, and may be lower in real-world settings than in trial settings, according to a study published in the April issue of the Archives of Dermatology. http://medicalxpress.com/news/2012-04-effectiveness-psoriasis-treatments.html Diseases, Conditions, Syndromes Fri, 20 Apr 2012 15:30:01 EST news254150335 Testing a breast cancer tumour for its genomic signature can help identify which patients will need adjuvant systemic therapy (additional chemotherapy) after surgery, and spare its use in those for whom it is not necessary, according to the results of a study to be presented to the 8th European Breast Cancer Conference (EBCC-8) today. Dr. Sabine Linn, an Associate Professor of Medical Oncology at The Netherlands Cancer Institute, Amsterdam, The Netherlands, will say that this is the first study where such a test has been incorporated in decision-making about adjuvant systemic therapy, and that the results are promising. http://medicalxpress.com/news/2012-03-genomic-patients-chemotherapy-adverse-effect.html Cancer Thu, 22 Mar 2012 09:01:09 EST news251625569 The journal Radiology will publish in its September issue an article written by Damian E. Dupuy, M.D., director of tumor ablation at Rhode Island Hospital, supporting the use of ablation procedures for the treatment of lung cancer. The article, "Image-guided Thermal Ablation of Lung Malignancies," reviews the results of nearly 100 studies conducted between 1991 and 2011 that conclude that image-guided ablation for lung cancer is a successful alternative for patients who cannot withstand surgery due to advanced age or medical comorbidities. http://medicalxpress.com/news/2011-08-thermal-ablation-lung-cancer.html Cancer Wed, 31 Aug 2011 09:50:53 EST news234003040