http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Researchers from Mount Sinai School of Medicine have identified a regulator protein that plays a crucial role in kidney fibrosis, a condition that leads to kidney failure. Finding this regulator provides a new therapeutic target for the millions of Americans affected by kidney failure. The research is published in the March 11 issue of Nature Medicine. http://medicalxpress.com/news/2012-03-drug-kidney-disease.html Diseases, Conditions, Syndromes Sun, 11 Mar 2012 14:00:18 EST news250690864 Investigators in the Massachusetts General Hospital (MGH) Center for Systems Biology have discovered a previously unknown type of immune cell, a B cell that can produce the important growth factor GM-CSF, which stimulates many other immune cells. They also found that these novel cells may help protect against the overwhelming, life-threatening immune reaction known as sepsis. http://medicalxpress.com/news/2012-01-newly-immune-cell-important-protector.html Immunology Thu, 12 Jan 2012 14:10:01 EST news245595518 For the first time, researchers have analyzed the multitude of microorganisms residing in the human gut as a complex, integrated biological system, rather than a set of separate species. Their approach has revealed patterns that correspond with excess body weight. http://medicalxpress.com/news/2012-01-gut-microbe-networks-differ-norm.html Medical research Tue, 10 Jan 2012 14:43:40 EST news245429006 When given for hours as a continuous dose, the heart medication nitroglycerin backfires -- increasing the severity of subsequent heart attacks, according to a study of the compound in rats by researchers at the Stanford University School of Medicine. http://medicalxpress.com/news/2011-11-nitroglycerin-severity-heart.html Cardiology Wed, 02 Nov 2011 14:06:00 EST news239461540 Taking aim at the alarming slowdown in the development of new and lifesaving drugs, Harvard Medical School is launching an Initiative in Systems Pharmacology, a comprehensive strategy to transform drug discovery by convening biologists, chemists, pharmacologists, physicists, computer scientists and clinicians to explore together how drugs work in complex systems. http://medicalxpress.com/news/2011-10-harvard-medical-school-major-crisis.html Medical research Mon, 17 Oct 2011 12:49:02 EST news238074532 Women with high-grade ovarian cancer live longer and respond better to platinum-based chemotherapy when their tumors have BRCA2 genetic mutations, researchers at The University of Texas MD Anderson Cancer Center and the Institute for Systems Biology report in the Oct. 12 issue of the Journal of the American Medical Association. http://medicalxpress.com/news/2011-10-ovarian-cancer-patients-survive-longer.html Cancer Tue, 11 Oct 2011 16:48:50 EST news237570516 Carefully tracking the rate of response of human lung tumors during the first weeks of treatment can predict which cancers will undergo sustained regression, suggests a new study by researchers at the Stanford University School of Medicine. http://medicalxpress.com/news/2011-10-math-formula-success-cancer-therapies.html Medical research Wed, 05 Oct 2011 14:00:01 EST news237038276 Daria Mochly-Rosen, PhD, was about as hardcore a basic science researcher as you can be. For more than 20 years, she lived and breathed basic research, reveling in the microscopic world where molecules formed, changed shape and danced with one another. The professor of chemical and systems biology was even known to sketch cartoons of them wearing fanciful hats. http://medicalxpress.com/news/2011-08-gap-drug-development.html Medications Mon, 08 Aug 2011 10:14:03 EST news232015008 EU-funded researchers have made good progress in understanding how cancer cells can sometimes resist the effects of chemotherapy. This new knowledge will move forward the development of increasingly effective cancer treatments and could go some way to reducing relapse, good news for cancer patients and scientists alike. http://medicalxpress.com/news/2011-07-latest-cancer-cells-react-chemotherapy.html Cancer Thu, 14 Jul 2011 09:30:03 EST news229853666 Conway Fellow, Professor William Watson and Professor John Fitzpatrick, UCD School of Medicine and Medical Science and Mater Misericordiae University Hospital recently received a translational research award for the validation of a panel of serum biomarkers to inform surgical intervention for prostate cancer. http://medicalxpress.com/news/2011-06-prostate-cancer-biomarkers-closer-clinical.html Cancer Fri, 17 Jun 2011 09:28:15 EST news227521664