http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. As if the story of breakthrough research were not enough, there is the story of the researcher. The accomplishment, in this case, is a rapid test for detecting devastating bacterial infections. The researcher is undergraduate pre-med student Kristin Wiggins, finishing her junior year at Northern Arizona University while working as an intern at Translational Genomics Research Institute North in Flagstaff. http://medicalxpress.com/news/2013-05-student-fast-contributes-life-saving-rapid.html Medical research Wed, 08 May 2013 09:20:02 EST news287220969 The safety and preliminary efficacy of a new class of tumor fighting drugs were reported today by Scottsdale Healthcare's Virginia G. Piper Cancer Center Clinical Trials and the Translational Genomics Research Institute (TGen). http://medicalxpress.com/news/2013-04-clinical-trial-class-cancer-drugs.html Cancer Tue, 09 Apr 2013 15:00:01 EST news284730889 The nanoparticle drug BIND-014 is effective against multiple solid tumors, according to results generated by the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare, and presented today at the American Association for Cancer Research (AACR) Annual Meeting 2013. http://medicalxpress.com/news/2013-04-clinical-trial-results-bind-aacr.html Cancer Tue, 09 Apr 2013 13:35:53 EST news284733345 The scientific benefits of whole genome sequencing at the Translational Genomics Research Institute (TGen) will be presented at the 14th International Myeloma Workshop, April 3-7 at the Kyoto International Conference Center. http://medicalxpress.com/news/2013-04-tgen-professor-discusses-benefits-genome.html Cancer Wed, 03 Apr 2013 09:51:25 EST news284201476 The FDA has approved a thyroid cancer drug successfully tested at Virginia G. Piper Cancer Center Clinical Trials, a partnership of Scottsdale Healthcare and the Translational Genomics Research Institute (TGen). http://medicalxpress.com/news/2013-03-cancer-drug-clinical-trial-fda.html Cancer Wed, 27 Mar 2013 09:56:56 EST news283597005 More northwest Ohio garden centers this spring are teaming up with an Arizona-based biomedical research organization to fight pancreatic cancer through the sale of purple flowers, which symbolize the nation's fourth leading cause of cancer death. http://medicalxpress.com/news/2013-03-purple-grow-campaign-season.html Cancer Tue, 19 Mar 2013 09:45:56 EST news282905150 A multi-center Phase III clinical trial demonstrates that Abraxane (nab-paclitaxel) plus gemcitabine is the first combination of cancer drugs to extend survival of late-stage pancreatic cancer patients compared to standard treatment. http://medicalxpress.com/news/2013-01-drug-combination-pancreatic-cancer-patient.html Cancer Tue, 22 Jan 2013 18:00:01 EST news278097991 A fast growing, flesh-eating fungus killed 5 people following a massive tornado that devastated Joplin, Mo., according to two new studies based on genomic sequencing by the Translational Genomics Research Institute (TGen) and the U.S. Centers for Disease Control and Prevention (CDC). http://medicalxpress.com/news/2012-12-fungus-responsible-deaths-massive-tornado.html Diseases, Conditions, Syndromes Fri, 14 Dec 2012 18:31:55 EST news274732305 Genomic sequencing has revealed therapeutic drug targets for difficult-to-treat, metastatic triple-negative breast cancer (TNBC), according to an unprecedented study by the Translational Genomic Research Institute (TGen) and US Oncology Research. http://medicalxpress.com/news/2012-12-tgen-us-oncology-treatment-metastatic-triple-negative.html Cancer Thu, 06 Dec 2012 15:19:37 EST news274029561 A new cancer drug combination demonstrated significant improvement in overall survival of late-stage pancreatic cancer patients compared to those receiving standard treatment, according to results of a Phase III clinical trial led by physicians from Scottsdale Healthcare's Virginia G. Cancer Center Clinical Trials, a partnership with the Translational Genomics Research Institute (TGen). http://medicalxpress.com/news/2012-11-phase-iii-worldwide-drug-patients.html Cancer Mon, 19 Nov 2012 13:14:23 EST news272553254 For the first time, researchers have provided a direct comparison of gene expression profiles from African-American and East African breast tissue samples, according to results presented at the Fifth AACR Conference on The Science of Cancer Health Disparities, held Oct. 27-30, 2012. http://medicalxpress.com/news/2012-10-genetic-advance-ethnic-differences-breast.html Cancer Mon, 29 Oct 2012 10:24:43 EST news270725044 Whole genome sequencing—spelling out all 3 billion letters in the human genome—"is an obvious and powerful method for advancing our understanding of pancreatic cancer," according to a new study from TGen, Mayo Clinic and Scottsdale Healthcare published today. http://medicalxpress.com/news/2012-10-wgs-multiple-pancreatic-cancer-patients.html Cancer Wed, 10 Oct 2012 17:00:08 EST news269106114 Knowing how tumors evolve can lead to new treatments that could help prevent cancer from recurring, according to a study published today by the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare. http://medicalxpress.com/news/2012-09-clonal-evolution-maxillary-sinus-carcinoma.html Cancer Fri, 28 Sep 2012 17:00:10 EST news268063040 A Phase I/II, multi-center trial designed to test the safety and preliminary efficacy of a first in class cancer treatment opened worldwide today at the Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen). PR610 is designed to become activated in tissues with low levels of oxygen, which is characteristic of many cancers. This "targeted" approach should deliver more active drug to cancer tissue and less active drug to normal tissue. http://medicalxpress.com/news/2012-08-non-small-cell-lung-cancer.html Cancer Wed, 29 Aug 2012 16:11:37 EST news265475483 Researchers at the Translational Genomics Research Institute (TGen) have developed a method of isolating biospecimens that could lead to a less costly, less invasive and more accurate way of diagnosing chronic kidney disease, or CKD. http://medicalxpress.com/news/2012-07-tgen-method-isolates-biospecimens-treatment.html Diseases, Conditions, Syndromes Wed, 11 Jul 2012 09:46:06 EST news261218753 The Translational Genomics Research Institute (TGen) and the Virginia G. Piper Cancer Center at Scottsdale Healthcare have conducted whole genome sequencing (WGS) of a rare nasal tract cancer called olfactory neuroblastoma (ONB). http://medicalxpress.com/news/2012-05-genome-sequencing-rare-olfactory-neuroblastoma.html Genetics Wed, 23 May 2012 17:00:22 EST news257010468 Arizona resident Evelyn Sorensen is in a far different place today than she was six months ago, thanks to a cutting-edge cancer clinical trial being conducted at the Virginia G. Piper Cancer Center at Scottsdale Healthcare in partnership with the Translational Genomics Research Institute (TGen). http://medicalxpress.com/news/2012-04-cancer-patient-lease-life-clinical.html Cancer Mon, 30 Apr 2012 04:50:01 EST news254977861 BIND Biosciences, a clinical-stage biopharmaceutical company developing a new class of highly selective targeted therapeutics called AccurinsTM, announced today the presentation of late-breaker clinical data for BIND-014, the lead drug candidate within a new class of targeted therapeutics that are programmed to concentrate at tumors, at the American Association for Cancer Research (AACR) 2012 Annual Meeting. BIND presented data from the ongoing Phase 1 clinical study of BIND-014, its targeted docetaxel Accurin, in patients with solid tumors that strongly translated from preclinical data, demonstrated safety and tolerability, and showed evidence of anti-tumor activity with six of 17 patients with advanced or metastatic solid tumor cancers. The preliminary Phase 1 data demonstrated partial response or stable disease in this heavily pretreated patient population with durable responses of up to six months in some cases. In addition, BIND-014 demonstrated evidence of anti-tumor activity in tumors for which conventional docetaxel is known to have minimal activity. http://medicalxpress.com/news/2012-04-late-breaker-clinical-aacr-bind-antitumor.html Cancer Wed, 04 Apr 2012 10:16:52 EST news252753402 The feasibility of selecting treatment based on individual molecular characteristics was demonstrated in a first-of-its kind pancreatic cancer clinical trial reported today by the Translational Genomics Research Institute (TGen) and the Virginia G. Piper Cancer Center at Scottsdale Healthcare. http://medicalxpress.com/news/2012-04-pancreatic-cancer-clinical-trial-results.html Cancer Tue, 03 Apr 2012 09:51:24 EST news252665467 Because cases of Triple-Negative Breast Cancer (TNBC) are so genetically different, whole-genome sequencing is needed to detect the subtle molecular differences that might point to specific treatments for individual patients. http://medicalxpress.com/news/2012-04-preliminary-whole-genome-sequencing-triple-negative-breast.html Cancer Mon, 02 Apr 2012 04:58:09 EST news252561463 Could blocking a testosterone receptor lead to a new way to treat an aggressive form of breast cancer? That's a question researchers at Mayo Clinic in Arizona and the Translational Genomics Research Institute (TGen) are exploring. Preliminary results of a Mayo Clinic - TGen collaborative study shows the testosterone receptor may be a potential target to attack in treating triple negative breast cancer (TNBC). http://medicalxpress.com/news/2012-03-role-testosterone-triple-negative-breast.html Cancer Fri, 23 Mar 2012 09:29:27 EST news251713731 Combination drug therapy may be needed to combat non-small cell lung cancer (NSCLC), according to a study by the Translational Genomics Research Institute (TGen) and Van Andel Research Institute (VARI). http://medicalxpress.com/news/2012-02-combination-drug-therapy-urged-lung.html Cancer Thu, 02 Feb 2012 17:00:02 EST news247414030 A new skin cancer drug tested for the first time in the world five years ago at the Virginia G. Piper Cancer Center at Scottsdale Healthcare just received expedited approval by the U.S. Food and Drug Administration, a remarkable accomplishment in new drug development. http://medicalxpress.com/news/2012-02-fda-skin-cancer-drug.html Cancer Wed, 01 Feb 2012 13:13:19 EST news247324388 A son's passion to find a cure for the cancer that claimed the life of his mother has led to a new series of clinical trials under a Translational Genomics Research Institute (TGen) initiative to find a cure for pancreatic cancer. http://medicalxpress.com/news/2011-12-seena-clinical-trials-pancreatic-cancer.html Cancer Thu, 01 Dec 2011 02:20:00 EST news241928392 A new drug targeting the PI3K gene in patients with advanced breast cancer shows promising results in an early phase I investigational study conducted at Virginia G. Piper Cancer at Scottsdale Healthcare, according to a presentation by oncologist Dr. Daniel D. Von Hoff at the 47th annual meeting of the American Society of Clinical Oncology (ASCO). http://medicalxpress.com/news/2011-07-tgen-virginia-piper-cancer-center.html Cancer Wed, 20 Jul 2011 13:51:11 EST news230388649 A family of naturally occurring plant compounds could help prevent or delay memory loss associated with Alzheimer's disease, according to a new study by the Translational Genomics Research Institute (TGen). http://medicalxpress.com/news/2011-05-compounds-alzheimer-disease.html Medical research Thu, 26 May 2011 13:42:12 EST news225636102