http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. By monitoring the behavior of a class of cells in the brains of living mice, neuroscientists at Johns Hopkins discovered that these cells remain highly dynamic in the adult brain, where they transform into cells that insulate nerve fibers and help form scars that aid in tissue repair. http://medicalxpress.com/news/2013-05-dynamic-behavior-progenitor-cells-brain.html Neuroscience Thu, 09 May 2013 15:50:11 EST news287333402 (Medical Xpress)—Waging an immunological war against a pathogen is not the body's only way to survive an infection. Sometimes tolerance, or learning to live with an invader, can be just as important. In tolerance the body lessens or repairs the damage that the pathogen causes. http://medicalxpress.com/news/2013-04-infections.html Immunology Mon, 29 Apr 2013 07:50:01 EST news286438914 Researchers at Micro Orthopaedics, Zhongnan Hospital of Wuhan University, led by Dr. Ai-xi Yu, have suggested that articular cartilage defects can be repaired by a novel thermo-sensitive injectable hydrogel engineered with gene modified bone marrow mesenchymal stromal cells (BMSCs). The chitosan and polyvinyl alcohol composite hydrogel containing hTGFβ-1 gene modified BMSCs was injected into rabbits with defective articular cartilage. Sixteen weeks later the defected cartilage regenerated and was proven to be hyaline cartilage. This work can be found in the January 2013 issue of Experimental Biology and Medicine. http://medicalxpress.com/news/2013-04-articular-cartilage-defects-gel-gene.html Arthritis & Rheumatism Tue, 23 Apr 2013 14:44:40 EST news285947076 (HealthDay)—Delivery of an SDF-1 encoding plasmid (JVS-100) acts a homing signal for stem cells and improves clinical status in patients with symptomatic heart failure due to ischemic cardiomyopathy (IsCM), according to a study published online Feb. 21 in Circulation Research. http://medicalxpress.com/news/2013-02-gene-therapy-stem-cells-heart.html Cardiology Fri, 22 Feb 2013 15:10:03 EST news280765743 Over 500 billion cells in our bodies will be replaced daily, yet natural selection has enabled us to develop defenses against the cellular mutations which could cause cancer. It is this relationship between evolution and the body's fight against cancer which is explored in a new special issue of the Open Access journal Evolutionary Applications. http://medicalxpress.com/news/2013-01-evolutionary-biology-cancer.html Cancer Tue, 22 Jan 2013 07:51:12 EST news278063465 A study published this month by researchers at the University of Toronto and Toronto's Princess Margaret Hospital has shown that cells derived from the umbilical cord, "Human Umbilical Cord PeriVascular Cells" (HUCPVCs), are more effective in restoring heart function after an acute myocardial infarction (in common parlance, a heart attack) in a pre-clinical model than a similar cell population derived from bone marrow. http://medicalxpress.com/news/2012-11-umbilical-cord-cells-outperform-bone.html Medical research Thu, 15 Nov 2012 12:29:11 EST news272204941 Blood-circulating immune cells can take over the essential immune surveillance of the brain, this is shown by scientists of the German Center for Neurodegenerative Diseases and the Hertie Institute for Clinical Brain Research in Tübingen. Their study, now published in PNAS, might indicate new ways of dealing with diseases of the nervous system. http://medicalxpress.com/news/2012-10-immune-cells-blood-dysfunctional-brain.html Medical research Mon, 22 Oct 2012 10:40:01 EST news270119780 Radiation therapy is one of the most widely used cancer treatments, but it often damages normal tissue and can lead to debilitating conditions. A class of drugs known as mammalian target of rapamycin (mTOR) inhibitors can prevent radiation-induced tissue damage in mice by protecting normal stem cells that are crucial for tissue repair, according to a preclinical study published by Cell Press in the September issue of the journal Cell Stem Cell. http://medicalxpress.com/news/2012-09-stem-cell-protecting-drug-side-effects-therapy.html Cancer Thu, 06 Sep 2012 12:00:12 EST news266148159 Tissue implants made of cells grown on a sponge-like scaffold have been shown in clinical trials to help heal arteries scarred by atherosclerosis and other vascular diseases. However, it has been unclear why some implants work better than others. http://medicalxpress.com/news/2012-08-success-tissue-grown.html Medical research Tue, 14 Aug 2012 11:15:04 EST news264161564 In the first human study of its kind, researchers found that using stem cells to re-grow craniofacial tissues—mainly bone—proved quicker, more effective and less invasive than traditional bone regeneration treatments. http://medicalxpress.com/news/2012-07-stem-cell-therapy-defects-injuries.html Medical research Mon, 30 Jul 2012 16:58:54 EST news262886324 A small, external bioreactor holding human cells pumped out an anti-inflammatory protein to prevent organ damage and other complications in a rat with acute inflammation caused by bacterial products in a model of sepsis, according to a report from researchers at the University of Pittsburgh School of Medicine and the McGowan Institute for Regenerative Medicine. The findings were published today in the inaugural issue of Disruptive Science and Technology. http://medicalxpress.com/news/2012-05-bio-hybrid-device-thermostat-inflammation-sepsis.html Inflammatory disorders Mon, 14 May 2012 10:02:40 EST news256208528 (Medical Xpress) -- A new technique for improving delivery of stem cells may lead to better and faster tissue repair, a breakthrough with promise for sports medicine and military populations. http://medicalxpress.com/news/2012-04-method-transplant-cell-delivery.html Medical research Tue, 03 Apr 2012 08:40:48 EST news252661228 Researchers have identified a new and relatively abundant pool of stem cells in the heart. The findings in the December issue of Cell Stem Cell, a Cell Press publication, show that these heart cells have the capacity for long-term expansion and can form a variety of cell types, including muscle, bone, neural and heart cells. http://medicalxpress.com/news/2011-12-newly-heart-stem-cells-muscle.html Medical research Thu, 01 Dec 2011 13:00:01 EST news241965520 There's more than one way to mop up after a flu infection. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania report in Nature Immunology that a previously unrecognized population of lung immune cells orchestrate the body's repair response following flu infection. http://medicalxpress.com/news/2011-10-rebooting-immune-cells-lung-tissues.html Medical research Mon, 03 Oct 2011 15:57:44 EST news236876253 Tissue deprived of oxygen (ischemia) is a serious health condition that can lead to damaged heart tissue following a heart attack and, in the case of peripheral arterial disease in limbs, amputation, particularly in diabetic patients. http://medicalxpress.com/news/2011-08-blood.html Medical research Mon, 01 Aug 2011 15:34:39 EST news231431574 Genetically engineered human cardiac stem cells helped repair damaged heart tissue and improved function after a heart attack, in a new animal study. http://medicalxpress.com/news/2011-07-genetically-cardiac-stem-cells-mouse.html Cardiology Tue, 19 Jul 2011 07:09:43 EST news230278166