http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Alzheimer's disease is on the rise, but researchers like Dr. Michael Devous expect the numbers to shift into reverse. "I think we're going to cure Alzheimer's disease, and we're not far away from it," said Devous, a professor and director of the NeuroImaging Core for the Alzheimer's Disease Center at the University of Texas Southwestern Medical Center. http://medicalxpress.com/news/2013-06-doctor-alzheimer-disease.html Alzheimer's disease & dementia Fri, 07 Jun 2013 12:40:01 EST news289823937 An anti-cancer drug reverses memory deficits in an Alzheimer's disease mouse model, University of Pittsburgh Graduate School of Public Health researchers confirm in the journal Science. http://medicalxpress.com/news/2013-05-drug-reverses-alzheimer-disease-deficits.html Alzheimer's disease & dementia Thu, 23 May 2013 14:06:26 EST news288536778 Researchers at Georgetown University Medical Center have used tiny doses of a leukemia drug to halt accumulation of toxic proteins linked to Parkinson's disease in the brains of mice. This finding provides the basis to plan a clinical trial in humans to study the effects. http://medicalxpress.com/news/2013-05-cancer-drug-build-up-toxic-brain.html Genetics Fri, 10 May 2013 00:10:02 EST news287338927 They identified blood-based biological markers that are associated with the build up of a toxic protein in the brain which occurs years before symptoms appear and irreversible brain damage has occurred. http://medicalxpress.com/news/2013-05-scientists-closer-screening-early-alzheimer.html Alzheimer's disease & dementia Wed, 01 May 2013 08:22:40 EST news286615351 Adding more color to your diet in the form of berries is encouraged by many nutrition experts. The protective effect of berries against inflammation has been documented in many studies. Diets supplemented with blueberries and strawberries have also been shown to improve behavior and cognitive functions in stressed young rats. http://medicalxpress.com/news/2013-04-evidence-berries-health-promoting-properties.html Health Sun, 21 Apr 2013 17:22:01 EST news285783715 A bizarre twist on the usual way proteins are made may explain mysterious symptoms in the grandparents of some children with mental disabilities. http://medicalxpress.com/news/2013-04-science-toxic-protein-unusual-brain.html Neuroscience Thu, 18 Apr 2013 12:18:39 EST news285506312 A new study found no evidence to support concerns that abnormal neurodegenerative disease proteins are "infectious" or transmitted from animals to humans or from one person to another. http://medicalxpress.com/news/2013-02-transmission-alzheimer-proteins-humans.html Alzheimer's disease & dementia Mon, 04 Feb 2013 16:00:03 EST news279198034 A new understanding of what takes place on the cellular level during the development of neurodegenerative diseases, such as Parkinson's, Alzheimer's, ALS and Huntington's diseases, offers promise towards possible new strategies for combating such diseases, say Hebrew University of Jerusalem researchers. http://medicalxpress.com/news/2012-12-srategies-neurodegenerative-diseases.html Medical research Thu, 06 Dec 2012 10:44:36 EST news274013065 Antibodies developed by researchers at Rensselaer Polytechnic Institute are unusually effective at preventing the formation of toxic protein particles linked to Alzheimer's disease and Parkinson's disease, as well as Type 2 diabetes, according to a new study. http://medicalxpress.com/news/2012-12-antibodies-combating-alzheimer-parkinson-disease.html Neuroscience Mon, 03 Dec 2012 12:51:26 EST news273761473 Scientists searching for ways to develop treatments for Huntington's disease (HD) just got a roadmap that could dramatically speed their discovery process. Researchers at the Buck Institute have used RNA interference (RNAi) technology to identify hundreds of "druggable" molecular targets linked to the toxicity associated with the devastating, ultimately fatal disease. The results from this unprecedented genome-scale screen in a human cell model of HD are published in the November 29, 2012 edition of PLOS Genetics. The work was is a collaboration between Buck Institute faculty members Robert E. Hughes, Ph.D., Sean Mooney, Ph.D., Lisa Ellerby, Ph.D. and Juan Botas, Ph.D. at the Baylor College of Medicine. http://medicalxpress.com/news/2012-11-genome-scale-hundreds-potential-drug-huntington.html Genetics Thu, 29 Nov 2012 17:32:16 EST news273432726 Last March, researchers at UCLA reported the development of a molecular compound called CLR01 that prevented toxic proteins associated with Parkinson's disease from binding together and killing the brain's neurons. http://medicalxpress.com/news/2012-11-potential-treatment-alzheimer-disease.html Alzheimer's disease & dementia Thu, 15 Nov 2012 15:23:42 EST news272215411 An enzyme that could represent a powerful new tool for combating Alzheimer's disease has been discovered by researchers at Mayo Clinic in Florida. The enzyme—known as BACE2—destroys beta-amyloid, a toxic protein fragment that litters the brains of patients who have the disease. The findings were published online Sept. 17 in the science journal Molecular Neurodegeneration. http://medicalxpress.com/news/2012-09-enzyme-alzheimer-disease.html Alzheimer's disease & dementia Mon, 17 Sep 2012 16:18:17 EST news267117401 A new light-based technique for measuring levels of the toxic protein that causes Huntington's disease (HD) has been used to demonstrate that the protein builds up gradually in blood cells. Published today in the Journal of Clinical Investigation, the findings shed light on how the protein causes damage in the brain, and could be useful for monitoring the progression of HD, or testing new drugs aimed at suppressing production of the harmful protein. http://medicalxpress.com/news/2012-09-toxic-protein-build-up-blood-huntington.html Neuroscience Mon, 17 Sep 2012 12:00:07 EST news267096211 With a single drug treatment, researchers at the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine can silence the mutated gene responsible for Huntington's disease, slowing and partially reversing progression of the fatal neurodegenerative disorder in animal models. http://medicalxpress.com/news/2012-06-drug-reverse-huntington-disease-symptoms.html Neuroscience Wed, 20 Jun 2012 12:00:01 EST news259411330 A vaccine which revives a promising but long-abandoned path to thwart Alzheimer's disease has cleared a key safety hurdle in human trials, researchers say. http://medicalxpress.com/news/2012-06-vaccine-trial-alzheimer-key-hurdle.html Alzheimer's disease & dementia Thu, 07 Jun 2012 09:18:17 EST news258279486 (HealthDay) -- Neurodegenerative diseases may be characterized by specific regions of the brain that are critical network epicenters, with disease-related vulnerability associated with shorter paths to the epicenter and greater total connectional flow, according to a study published in the March 22 issue of Neuron. http://medicalxpress.com/news/2012-03-transneuronal-neurodegenerative-disease.html Neuroscience Sat, 24 Mar 2012 06:47:54 EST news251790425 Researchers at Weill Cornell Medical College have developed a computer program that has tracked the manner in which different forms of dementia spread within a human brain. They say their mathematic model can be used to predict where and approximately when an individual patient's brain will suffer from the spread, neuron to neuron, of "prion-like" toxic proteins -- a process they say underlies all forms of dementia. http://medicalxpress.com/news/2012-03-dementia-future-disease-patterns-years.html Neuroscience Wed, 21 Mar 2012 14:42:28 EST news251559739 (Medical Xpress) -- More than 32 million Americans harbor potentially toxic proteins that can attack body tissues and lead to autoimmune diseases such as lupus and scleroderma, according to a new University of Florida study. http://medicalxpress.com/news/2012-03-traitor-proteins-body-widespread.html Immunology Fri, 02 Mar 2012 06:05:20 EST news249890705 A red dye derived from lichens that has been used for centuries to color fabrics and food appears to reduce the abundance of small toxic protein aggregates in Alzheimer's disease. The dye, a compound called orcein, and a related substance, called O4, bind preferentially to small amyloid aggregates that are considered to be toxic and cause neuronal dysfunction and memory impairment in Alzheimer's disease. http://medicalxpress.com/news/2011-12-natural-dye-lichens-combat-alzheimer.html Medical research Fri, 02 Dec 2011 10:20:03 EST news242042259 Sluggish recycling of a protein-slicing enzyme could promote Alzheimer's disease, according to a study published online on November 21 in The Journal of Cell Biology. http://medicalxpress.com/news/2011-11-poor-recycling-bace1-enzyme-alzheimer.html Medical research Mon, 21 Nov 2011 12:00:03 EST news241097829 Researchers at Lund University have discovered a new function for vitamin C. Treatment with vitamin C can dissolve the toxic protein aggregates that build up in the brain in Alzheimer's disease. The research findings are now being presented in the Journal of Biological Chemistry. http://medicalxpress.com/news/2011-08-treatment-vitamin-dissolves-toxic-protein.html Medical research Thu, 18 Aug 2011 10:33:40 EST news232882391 A novel therapy that reduces elevated blood levels of a potentially toxic protein in women with preeclampsia, a dangerous complication of pregnancy, may someday address the therapeutic dilemma posed by the condition – balancing life-threatening risks to the mother with the dangers that early delivery poses to an immature fetus. In a paper receiving online release in the journal Circulation, a team of U.S. and German researchers report promising results from their pilot study of a filtration technology that reduces reduce excess blood levels of soluble Flt-1, a protein that limits the growth of blood vessels, in women with very preterm preeclampsia. http://medicalxpress.com/news/2011-08-approach-preeclampsia.html Health Tue, 02 Aug 2011 12:40:04 EST news231505358 Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson's disease (PD) in a mouse model of the condition. http://medicalxpress.com/news/2011-06-lithium-profoundly-brain-parkinson-disease.html Parkinson's & Movement disorders Fri, 24 Jun 2011 04:14:26 EST news228107624 National Institutes of Health researchers have identified a new pathway that sets the clock for programmed aging in normal cells. The study provides insights about the interaction between a toxic protein called progerin and telomeres, which cap the ends of chromosomes like aglets, the plastic tips that bind the ends of shoelaces. http://medicalxpress.com/news/2011-06-nih-clues-aging.html Medical research Mon, 13 Jun 2011 12:57:35 EST news227188620