http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Researchers at Moffitt Cancer Center have identified metabolic signatures that may pave the way for personalized therapy in glioma, a type of tumor that starts in the brain. http://medicalxpress.com/news/2012-11-metabolic-aggressive-brain-tumors.html Cancer Fri, 09 Nov 2012 13:15:53 EST news271689336 Genomic deletions promote cancer by carving up or eliminating tumor-suppressor genes, but now scientists report in the journal Nature that the collateral damage they inflict on neighboring genes exposes cancer cells to vulnerabilities and new avenues for attack. http://medicalxpress.com/news/2012-08-dna-deletions-cancer-collateral-vulnerable.html Cancer Wed, 15 Aug 2012 13:00:06 EST news264251418 It has long been known that cancer is a disease of aging, but a molecular link between the two has remained elusive. http://medicalxpress.com/news/2012-06-aging-cells-fuels-tumor-growth.html Cancer Thu, 14 Jun 2012 14:59:36 EST news258904683 Researchers at the Kimmel Cancer Center at Jefferson have demonstrated for the first time that the metabolic biomarker MCT4 directly links clinical outcomes with a new model of tumor metabolism that has patients "feeding" their cancer cells. Their findings were published online March 15 in Cell Cycle. http://medicalxpress.com/news/2012-03-cancer-paradigm-shift-biomarker-links.html Cancer Thu, 15 Mar 2012 17:33:38 EST news251051606 Cancer cells are well known for their altered metabolisms, which may help them generate the energy they need for rapid growth. Using an emerging imaging technology, researchers reporting in the July Cell Metabolism, a Cell Press publication, have discovered that those metabolic shifts actually develop even before detectable tumors form. By the same token, the studies in mice with liver cancer show that the altered tumor metabolism shifts back before established tumors shrink. http://medicalxpress.com/news/2011-07-metabolic-shift-early-cancer-clue.html Cancer Tue, 05 Jul 2011 12:31:25 EST news229087865