http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. A new class of investigational medicines may help to treat patients with cancers driven by mutations in genes such as BRAF or KRAS/NRAS, including those patients who have become resistant to therapies that target BRAF directly, according to preclinical data presented at the AACR Annual Meeting 2013, held in Washington, D.C., April 6-10. http://medicalxpress.com/news/2013-04-preclinical-potential-inhibitor-drug-resistance.html Cancer Mon, 08 Apr 2013 09:20:04 EST news284629264 Drugs that are used in the clinic to treat some forms of breast and kidney cancer and that work by inhibiting the signaling molecule mTORC1 might have utility in treating some of the more than 15 percent of human cancers driven by alterations in the Myc gene, according to data from a preclinical study published in Cancer Discovery, a journal of the American Association for Cancer Research. http://medicalxpress.com/news/2012-12-hard-to-treat-myc-driven-cancers-susceptible-drug.html Cancer Fri, 14 Dec 2012 10:00:01 EST news274695612 Select patients with advanced prostate cancer may benefit from a Georgia Health Sciences University Cancer Center clinical trial that looks to improve survival rates of the FDA-approved prostate cancer drug Provenge. http://medicalxpress.com/news/2012-12-clinical-trial-advanced-prostate-cancer.html Cancer Mon, 03 Dec 2012 12:43:35 EST news273761006 Melanoma is the most deadly form of skin cancer, estimated by the National Cancer Institute to afflict more than 70,000 people in the United States annually and the incidence rate continues to rise. In a study published online in Genome Research, researchers have identified a previously unknown non-coding RNA that plays an important role in the biology of melanoma, a finding that could lead to a new target for therapy. http://medicalxpress.com/news/2012-05-rna-melanoma-cancer-therapy.html Cancer Thu, 10 May 2012 17:00:01 EST news255876694 Researchers at Moffitt Cancer Center in Tampa, Fla., and colleagues in California have found that the XL888 inhibitor can prevent resistance to the chemotherapy drug vemurafenib, commonly used for treating patients with melanoma. http://medicalxpress.com/news/2012-02-potential-solution-melanoma-resistance-vemurafenib.html Cancer Tue, 28 Feb 2012 16:33:32 EST news249669204 As soon as women quit hormone therapy, their rates of new breast cancer decline, supporting the hypothesis that stopping hormones can lead to tumor regression, according to a report e-published in Cancer Epidemiology, Biomarkers, & Prevention. http://medicalxpress.com/news/2012-02-hormones-breast-cancer-regress.html Cancer Tue, 28 Feb 2012 15:43:17 EST news249666192 Researchers at Brigham and Women's Hospital (BWH) have identified a new combination of targeted therapies that, together, may treat two aggressive tumor types that until now have not had effective treatments. These findings are published in Cancer Cell on September 13, 2011. http://medicalxpress.com/news/2011-09-drug-combination-therapeutic-hard-to-treat-cancers.html Cancer Mon, 12 Sep 2011 16:16:43 EST news235062863 A new study has shown that magnetic resonance imaging (MRI) used to evaluate responses to pre-surgery (neo-adjuvant) chemotherapy or radiation may predict survival among patients with advanced rectal cancer. The findings suggest that MRI-assessed tumor responses to neoadjuvant therapy can help physicians to better plan their patients' subsequent treatments. http://medicalxpress.com/news/2011-08-mri-survival-locally-advanced-rectal.html Cancer Mon, 29 Aug 2011 16:00:05 EST news233847271