http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Despite previous studies touting its benefit in moderating gout risk, new research reveals that vitamin C, also known ascorbic acid, does not reduce uric acid (urate) levels to a clinically significant degree in patients with established gout. Vitamin C supplementation, alone or in combination with allopurinol, appears to have a weak effect on lowering uric acid levels in gout patients according to the results published in the American College of Rheumatology (ACR) journal, Arthritis & Rheumatism. http://medicalxpress.com/news/2013-05-vitamin-uric-acid-gout-patients.html Health Thu, 16 May 2013 00:00:02 EST news287856837 Johns Hopkins scientists have found out how a gout-linked genetic mutation contributes to the disease: by causing a breakdown in a cellular pump that clears an acidic waste product from the bloodstream. By comparing this protein pump to a related protein involved in cystic fibrosis, the researchers also identified a compound that partially repairs the pump in laboratory tests. http://medicalxpress.com/news/2013-04-protein-well-known-cousin-gout-linked-relative.html Medical research Mon, 08 Apr 2013 13:08:56 EST news284645322 Findings from a Loyola University Chicago Stritch School of Medicine study could lead to the development of new drugs to treat gout. The study, led by Liang Qiao, MD, and his colleagues and collaborators, was published March 19 in the journal Nature Communications. http://medicalxpress.com/news/2013-03-aid-drugs-gout.html Immunology Tue, 19 Mar 2013 16:02:20 EST news282927733 Scientists have shed light on why some people are more susceptible to gout than others. A study has identified 18 new genetic variations that increase levels of uric acid in the blood, which is the main cause of the disease. High levels of uric acid form small crystals in joints and tissues, causing pain and swelling – the main symptoms of the condition once known as the 'disease of kings'. http://medicalxpress.com/news/2012-12-gout-genetic-insight-disease-kings.html Genetics Sun, 23 Dec 2012 13:00:19 EST news275489221 Obese patients with type 2 diabetes who consume higher amounts of fructose display reduced levels of liver adenosine triphosphate (ATP)—a compound involved in the energy transfer between cells. The findings, published in the September issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, indicate that elevated uric acid levels (hyperuricemia) are associated with more severe hepatic ATP depletion in response to fructose intake. http://medicalxpress.com/news/2012-09-dietary-fructose-linked-elevated-uric.html Diseases, Conditions, Syndromes Thu, 13 Sep 2012 11:56:49 EST news266756170 Researchers from Boston University School of Medicine (BUSM) have found that the incidence of gout and hyperuricemia (high uric acid levels) in the U.S. has risen significantly over the last 20 years and is associated with major medical disorders like hypertension and chronic kidney disease. The study, which is published in the American Journal of Medicine, was led by Hyon Choi, MD, DrPH, professor of medicine in the section of rheumatology and the clinical epidemiology unit at BUSM and rheumatologist at Boston Medical Center (BMC). http://medicalxpress.com/news/2012-06-gout-hyperuricemia.html Diseases, Conditions, Syndromes Tue, 26 Jun 2012 14:56:02 EST news259941355 Obese people who consume increased amounts of fructose, a type of sugar that is found in particular in soft drinks and fruit juices, are at risk for nonalcoholic fatty liver disease (NFALD) and more its more severe forms, fatty inflammation and scarring. http://medicalxpress.com/news/2012-05-fructose-consumption-deplete-cellular-energy.html Diseases, Conditions, Syndromes Wed, 02 May 2012 12:20:01 EST news255177994 Teens with high levels of uric acid appear to be at increased risk for high blood pressure, according to results of research from scientists at the Johns Hopkins Children's Center. http://medicalxpress.com/news/2012-05-abnormal-uric-acid-teens-linked.html Health Tue, 01 May 2012 11:05:22 EST news255089005 (HealthDay) -- Elevated uric acid levels are predictive of one-year mortality in patients with acute coronary syndrome, according to a study published in the May 1 issue of The American Journal of Cardiology. http://medicalxpress.com/news/2012-04-uric-acid-death-acute-coronary.html Cardiology Fri, 20 Apr 2012 15:20:01 EST news254150249 X-ray images known as CT scans can help confirm gout in patients who are suspected of having the painful condition but receive negative results from traditional tests, a Mayo Clinic study has found. The type of CT scan analyzed, dual-energy computed tomography, also is valuable for diagnosing people who cannot be tested with the typical method of drawing fluid from joints, researchers found. The study is being presented at the American College of Rheumatology annual scientific meeting in Chicago. http://medicalxpress.com/news/2011-11-ct-scans-gout-cases-traditional.html Cancer Sun, 06 Nov 2011 07:00:01 EST news239784221 Injections of pegloticase, a modified porcine enzyme, can produce significant and sustained clinical improvements in 2 out of 5 patients with chronic gout that is resistant to conventional therapies, researchers report in the August 17, 2011, issue of JAMA. http://medicalxpress.com/news/2011-08-drug-aids-gout-patients-standard.html Diseases, Conditions, Syndromes Tue, 16 Aug 2011 16:35:55 EST news232731301