http://medicalxpress.com/ en-us Medical Xpress internet news portal provides the latest news on Health and Medicine. Atherosclerosis – sometimes called "hardening of the arteries" – is a leading cause of death and morbidity in Western countries. A cell-permeable peptide containing the NF-kB nuclear localization sequence (NLS) shows promise as a potential agent in controlling the development of atherosclerotic disease. This study is published in the May 2013 issue of The American Journal of Pathology. http://medicalxpress.com/news/2013-04-cell-permeable-peptide-cardiovascular-disease.html Cardiology Wed, 17 Apr 2013 06:22:09 EST news285398523 (Medical Xpress)—Impairment of a key signaling cascade in the pulmonary blood vessels plays an important role in pulmonary arterial hypertension, a Yale study has found. The study appears in the advance online publication of Nature Medicine. http://medicalxpress.com/news/2012-12-disruption-cellular-pulmonary-arterial-hypertension.html Medical research Thu, 27 Dec 2012 15:39:21 EST news275845147 (Medical Xpress)—Growing new blood vessels in the lab is a tough challenge, but a Johns Hopkins engineering team has solved a major stumbling block: how to prod stem cells to become two different types of tissue that are needed to build tiny networks of veins and arteries. http://medicalxpress.com/news/2012-12-stem-cells-blocks-blood-vessels.html Cardiology Thu, 20 Dec 2012 15:45:42 EST news275240732 Each year, about 610,000 Americans suffer their first heart attack, according to the Centers for Disease Control and Prevention. Heart attacks and other symptoms of cardiovascular disease can be caused when blockage occurs in the arteries. In a new study from the University of Missouri, a scientist has discovered a natural defense against arterial blockage: bilirubin. http://medicalxpress.com/news/2012-12-bilirubin-cardiovascular-disease.html Cardiology Thu, 06 Dec 2012 10:41:42 EST news274012887 Researchers at St. Michael's Hospital are one step closer to understanding why plaque bursts in coronary arteries and causes heart attacks. http://medicalxpress.com/news/2012-09-closer-actions-cells-involved-atherosclerosis.html Cardiology Mon, 10 Sep 2012 16:43:22 EST news266514197 A Cambridge University research team has for the first time discovered a method of generating different types of vascular smooth muscle cells (SMCs) - the cells which make up the walls of blood vessels - using cells from patients' skin. This work could lead to new treatments and better screening for cardiovascular disease. http://medicalxpress.com/news/2012-01-cambridge-team-smooth-muscle-cells.html Cardiology Thu, 26 Jan 2012 08:08:14 EST news246787679 There is an observed correlation between Immunoglobulin E (IgE) levels atherosclerosis, with twice amount of IgE present in patients with acute myocardial infarction as in patients with stable angina or without coronary heart disease (CHD). Guo-Ping Shi, DSc, Jing Wang, MD, PhD, and colleagues in the Department of Medicine at Brigham and Women's Hospital (BWH), have demonstrated the direct participation of IgE in atherogenesis in a mouse model. These findings appear in the August 8, 2011 issue of Journal of Clinical Investigation. http://medicalxpress.com/news/2011-08-link-immunoglobulin-atherogenesis.html Medical research Tue, 09 Aug 2011 11:00:45 EST news232105128