News tagged with aberrations
Gene mutation can allow proteins to gather, spark tumor growth
Prostate cancer is generally treated as if it's a single disease. But researchers have discovered a new type of the cancer that appears to affect 15 percent of patients, a finding that paves the way for better diagnosis and ...
Cancer
Sep 07, 2012 |
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Cell-CT: A new dimension in breast cancer research
Despite advances in both the diagnosis and treatment of breast cancer, the disease remains a leading worldwide health concern.
Cancer
Jan 05, 2012 |
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Baby's genome deciphered prenatally from parents' lab tests
Scientists have successfully sequenced the genome of a baby in the womb without tapping its protective fluid sac. This non-invasive approach to obtaining the fetal genome is reported in the June 6 issue of ...
Genetics
Jun 06, 2012 |
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Genetic sequencing could help match patients with biomarker-driven cancer trials, treatments
As cancer researchers continue to identify genetic mutations driving different cancer subtypes, they are also creating a catalog of possible targets for new treatments.
Cancer
Nov 30, 2011 |
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Two gene mutations drive adrenal cancer
Two different genetic mutations cooperate to induce adrenal cancer, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center and University of Sao Paulo in Brazil.
Cancer
Sep 10, 2012 |
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Analysis of social media use could give therapists more complete view of patients' health
Facebook activity provided a window into the psychological health of participants in a study at the University of Missouri. Social media profiles could eventually be used as tools for psychologists and therapists, according ...
Psychology & Psychiatry
Jan 25, 2013 |
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Autism may be linked to abnormal immune system characteristics and novel protein fragment
Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida's Department of Psychiatry ...
Immunology
Jan 03, 2012 |
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New computational pipeline analyzes tumor images, may help predict response to cancer therapy
(Medical Xpress)—How's this for big data: A whole-slide image of a tumor section can be ten billion pixels. There can be thousands of such images in the tumor cohorts maintained by The Cancer Genome Atlas ...
Cancer
Feb 01, 2013 |
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Children exposed to the common pollutant naphthalene show signs of chromosomal damage
According to a new study, children exposed to high levels of the common air pollutant naphthalene are at increased risk for chromosomal aberrations (CAs), which have been previously associated with cancer. These include chromosomal ...
Health
May 29, 2012 |
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Patterns of chromosome abnormality: The key to cancer?
A healthy genome is characterized by 23 pairs of chromosomes, and even a small change in this structure — such as an extra copy of a single chromosome — can lead to severe physical impairment. So it's no surprise ...
Cancer
Jan 23, 2012 |
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Intratumor heterogeneity seen in renal carcinomas
(HealthDay) -- Extensive intratumor heterogeneity, seen in samples obtained from renal carcinomas, may lead to underestimation of the tumor genomics based on single tumor-biopsy samples, according to a study ...
Cancer
Mar 08, 2012 |
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New findings validate the accuracy of autism diagnosis in children with Down syndrome
New findings from a 16-year study confirm that the Diagnostic and Statistic Manual of Mental Disorders (DSM), the gold-standard for the classification of mental health conditions, can be used to accurately identify autism ...
Diseases, Conditions, Syndromes
Oct 04, 2011 |
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Novel test identifies patients most likely to benefit from ALK inhibition therapy
Approximately one in 20 patients with non-small cell lung carcinoma (NSCLC) has chromosomal aberrations targeting the anaplastic lymphoma kinase (ALK) gene. This has considerable implications for treatment because these patients ...
Medical research
Dec 12, 2012 |
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A new mechanism that contributes to the evolution of cancer
Cancer arises from the accumulation of mutations and structural changes in chromosomes, which in some cases give rise to combinations that favour the growth or expansion of the disease. In this context, chromosomes tend to ...
Cancer
Jan 31, 2013 |
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Patients with aberrations in two genes respond better to drugs blocking a well-known cancer pathway
Cancer patients with mutations or variations in two genes -– PIK3CA and PTEN -– who have failed to respond to several, standard treatments, respond significantly better to anti-cancer drugs that inhibit these genes' pathways ...
Cancer
Nov 07, 2012 |
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