Drug shows promise in animal model of Alzheimer's and Parkinson's with dementia
New research presented in October at the 6th Neurodegenerative Conditions Research and Development Conference in San Francisco demonstrates the role of the investigational compound IRX4204 in alleviating cognitive decline ...
Alzheimer's disease & dementia
Oct 26, 2012 |
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Discovery sheds light on Alzheimer's mystery
(Medical Xpress)—In 1906, when Alois Alzheimer discovered the neurodegenerative disease that would later be named for him, he saw amyloid-beta plaques and neurofibrillary tangles inside the brain. Several decades later, ...
Alzheimer's disease & dementia
Oct 22, 2012 |
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Targeting cancers' 'addiction' to cell-cycle proteins shuts down tumors in mice
In what they say is a promising and highly selective treatment strategy, scientists at Dana-Farber Cancer Institute have safely shut down breast cancer and a form of leukemia in mice by targeting abnormal proteins to which ...
Cancer
Oct 16, 2012 |
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New research model to aid search for degenerative disease cures
(Medical Xpress)—Efforts to treat disorders like Lou Gehrig's disease, Paget's disease, inclusion body myopathy and dementia will receive a considerable boost from a new research model created by UC Irvine scientists.
Medical research
Oct 02, 2012 |
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Impaired protein degradation causes muscle diseases
New insights into certain muscle diseases, the filaminopathies, are reported by an international research team led by Dr. Rudolf Andre Kley of the RUB's University Hospital Bergmannsheil in the journal Brain. The scientists from t ...
Medical research
Sep 25, 2012 |
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Collagen-seeking synthetic protein could lead doctors to tumor locations
Johns Hopkins researchers have created a synthetic protein that, when activated by ultraviolet light, can guide doctors to places within the body where cancer, arthritis and other serious medical disorders ...
Medical research
Aug 29, 2012 |
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'Alzheimer protein' seems to slow down neurotransmitter production
Researchers report how abnormal protein deposits in the brains of Alzheimer's patients disrupt the signaling between nerve cells. They varied the amount of APP protein and related proteins associated with Alzheimer's disease ...
Alzheimer's disease & dementia
Aug 21, 2012 |
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Mayo Clinic completes first genome-wide analysis of peripheral T-cell lymphomas
Researchers at Mayo Clinic have completed the world's first genome-wide sequencing analysis of peripheral T-cell lymphomas, unlocking the genetic secrets of this poorly understood and highly aggressive cancer of the immune ...
Cancer
Aug 01, 2012 |
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New mouse model helps explain gene discovery in congenital heart disease
Scientists now have clues to how a gene mutation discovered in families affected with congenital heart disease leads to underdevelopment of the walls that separate the heart into four chambers. A Nationwide Children's Hospital ...
Genetics
Jun 26, 2012 |
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Coenzyme Q10 study indicates promise in Huntington's treatment
A new study shows that the compound Coenzyme Q10 (CoQ) reduces oxidative damage, a key finding that hints at its potential to slow the progression of Huntington disease. The discovery, which appears in the inaugural issue ...
Neuroscience
Jun 18, 2012 |
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Clusters of cooperating tumor-suppressor genes are found in large regions deleted in common cancers
Scientists at Cold Spring Harbor Laboratory (CSHL) and Memorial Sloan-Kettering Cancer Center have amassed strong experimental evidence implying that commonly occurring large chromosomal deletions that are seen in many cancer ...
Cancer
May 07, 2012 |
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Long-term cardiac effects for childhood cancer survivors
(HealthDay) -- Regardless of exposure to cardiotoxic cancer therapies, survivors of childhood cancers display cardiovascular abnormalities and have markers of increased systemic inflammation and atherosclerotic ...
Cancer
Mar 07, 2012 |
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New universal platform for cancer immunotherapy developed
(Medical Xpress) -- Researchers from the Perelman School of Medicine at the University of Pennsylvania report this month in Cancer Research a universal approach to personalized cancer therapy based on T c ...
Cancer
Mar 05, 2012 |
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Understanding and treating the cognitive dysfunction of Down syndrome and Alzheimer's disease
Down syndrome (DS) is the most common genetic disorder in live born children arising as a consequence of a chromosomal abnormality. It occurs as a result of having three copies of chromosome 21, instead of the usual two. ...
Psychology & Psychiatry
Mar 01, 2012 |
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'Popeye' proteins help the heart adapt to stress
(Medical Xpress) -- A family of proteins named after Popeye play an essential role in allowing the heart to respond to stress, according to a study published today in the Journal of Clinical Investigation. The fi ...
Medical research
Feb 24, 2012 |
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