The Parkinson's puzzle: Developing an assay to identify components in protein structures to aid diagnosis, treatment
As part of a new initiative to speed the search for changes in the body that can help predict, diagnose, or monitor Parkinson's disease, a research team led by Pacific Northwest National Laboratory recently ...
Parkinson's & Movement disorders
Mar 26, 2013 |
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Worming our way to new treatments for Alzheimer's disease
According to a 2012 World Health Organization report, over 35 million people worldwide currently have dementia, a number that is expected to double by 2030 (66 million) and triple by 2050 (115 million). Alzheimer's disease, ...
Alzheimer's disease & dementia
Mar 07, 2013 |
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Scientists identify 'clean-up' snafu that kills brain cells in Parkinson's disease
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells. The study, which published online today in ...
Parkinson's & Movement disorders
Mar 03, 2013 |
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Study finds possible link between diabetes and increased risk of heart attack death
Having diabetes doubles a person's risk of dying after a heart attack, but the reason for the increased risk is not clear. A new University of Iowa study suggests the link may lie in the over-activation of an important heart ...
Cardiology
Feb 15, 2013 |
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Identification of abnormal protein may help diagnose, treat ALS and frontotemporal dementia
Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, and frontotemporal dementia (FTD) are devastating neurodegenerative diseases with no effective treatment. Researchers are beginning to recognize ...
Alzheimer's disease & dementia
Feb 12, 2013 |
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Vitamin D, omega-3 may help clear amyloid plaques found in Alzheimer's
A team of academic researchers has pinpointed how vitamin D3 and omega-3 fatty acids may enhance the immune system's ability to clear the brain of amyloid plaques, one of the hallmarks of Alzheimer's disease.
Alzheimer's disease & dementia
Feb 05, 2013 |
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A new mechanism that contributes to the evolution of cancer
Cancer arises from the accumulation of mutations and structural changes in chromosomes, which in some cases give rise to combinations that favour the growth or expansion of the disease. In this context, chromosomes tend to ...
Cancer
Jan 31, 2013 |
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Study deflates notion that pear-shaped bodies more healthy than apples
People who are "apple-shaped"—with fat more concentrated around the abdomen—have long been considered more at risk for conditions such as heart disease and diabetes than those who are "pear-shaped" and ...
Health
Jan 10, 2013 |
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Saliva gland test for Parkinson's shows promise
Described as a "big step forward" for research and treatment of Parkinson's disease, new research from Mayo Clinic in Arizona and Banner Sun Health Research Institute suggests that testing a portion of a person's saliva gland ...
Parkinson's & Movement disorders
Jan 10, 2013 |
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New research discovery provides therapeutic target for ALS
Research led by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, has found that the ability of a protein made by a gene called FUS to bind to RNA is essential to the development ...
Genetics
Dec 19, 2012 |
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Clinical trial delivers good results in leukemia patients
Huntsman Cancer Institute (HCI) researchers Michael Deininger, M.D., Ph.D., and Thomas O'Hare, Ph.D., were part of a team that found a potent oral drug, ponatinib, effective in patients who have developed resistance to standard ...
Cancer
Nov 30, 2012 |
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Enzyme inhibition protects against Huntington's disease damage in two animal models
Treatment with a novel agent that inhibits the activity of SIRT2, an enzyme that regulates many important cellular functions, reduced neurological damage, slowed the loss of motor function and extended survival in two animal ...
Neuroscience
Nov 29, 2012 |
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Ponatinib acts against the most resistant types of chronic myeloid leukemia
A previously invincible mutation in chronic myeloid leukemia (CML) has been thwarted by an investigational drug in a phase I clinical trial reported in the current edition of The New England Journal of Medicine.
Cancer
Nov 28, 2012 |
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Alzheimer's disease in mice alleviated promising therapeutic approach for humans
Pathological changes typical of Alzheimer's disease were significantly reduced in mice by blockade of an immune system transmitter. A research team from Charité - Universitätsmedizin Berlin and the University ...
Alzheimer's disease & dementia
Nov 25, 2012 |
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Gene sequencing project identifies abnormal gene that launches rare childhood leukemia
Research led by the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project has identified a fusion gene responsible for almost 30 percent of a rare subtype of childhood leukemia with ...
Cancer
Nov 12, 2012 |
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