News tagged with acid

Novel oncogenic RET mutation found in small cell lung cancer

For the first time an oncogenic somatic mutation at amino acid 918 in the RET (rearranged during transfection) protein has been identified in small cell lung cancer (SCLC) tumors and enforced expression of this mutation within ...

4 hours ago
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Novel drug action against solid tumors explained

Researchers at UC Davis, City of Hope, Taipai Medical University and National Health Research Institutes in Taiwan have discovered how a drug that deprives the cells of a key amino acid specifically kills ...

Aug 11, 2014
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Lipids boost the brain

Consuming oils with high polyunsaturated fatty acid content, in particular those containing omega-3s, is beneficial for the health. But the mechanisms underlying this phenomenon are poorly known. Researchers ...

Aug 11, 2014
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How can I control my appetite?

James M. Greenblatt, an assistant clinical professor of psychiatry at the Tufts School of Medicine and author of "Answers to Appetite Control," offers his advice.

Aug 11, 2014
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Acid

An acid (from the Latin acidus/acēre meaning sour) is a substance which reacts with a base. Commonly, acids can be identified as tasting sour, reacting with metals such as calcium, and bases like sodium carbonate. Aqueous acids have a pH of less than 7, where an acid of lower pH is typically stronger, and turn blue litmus paper red. Chemicals or substances having the property of an acid are said to be acidic.

Common examples of acids include acetic acid (in vinegar), sulfuric acid (used in car batteries), and tartaric acid (used in baking). As these three examples show, acids can be solutions, liquids, or solids. Gases such as hydrogen chloride can be acids as well. Strong acids and some concentrated weak acids are corrosive, but there are exceptions such as carboranes and boric acid.

There are three common definitions for acids: the Arrhenius definition, the Brønsted-Lowry definition, and the Lewis definition. The Arrhenius definition states that acids are substances which increase the concentration of hydronium ions (H3O+) in solution. The Brønsted-Lowry definition is an expansion: an acid is a substance which can act as a proton donor. Most acids encountered in everyday life are aqueous solutions, or can be dissolved in water, and these two definitions are most relevant. The reason why pHs of acids are less than 7 is that the concentration of hydronium ions is greater than 10−7 moles per liter. Since pH is defined as the negative logarithm of the concentration of hydronium ions, acids thus have pHs of less than 7. By the Brønsted-Lowry definition, any compound which can easily be deprotonated can be considered an acid. Examples include alcohols and amines which contain O-H or N-H fragments.

In chemistry, the Lewis definition of acidity is frequently encountered. Lewis acids are electron-pair acceptors. Examples of Lewis acids include all metal cations, and electron-deficient molecules such as boron trifluoride and aluminium trichloride. Hydronium ions are acids according to all three definitions. Interestingly, although alcohols and amines can be Brønsted-Lowry acids as mentioned above, they can also function as Lewis bases due to the lone pairs of electrons on their oxygen and nitrogen atoms.

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