'Druggable' protein complex identified as a therapeutic target in acute myeloid leukemia
Scientists at Cold Spring Harbor Laboratory have identified a candidate drug target for treating acute myeloid leukemia (AML), a white blood cell cancer that proliferates out of control in the bone marrow. The team, led by ...
Cancer
Apr 02, 2012 |
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Identifying acute myeloid leukemia gene mutations may indicate risk, best treatment
An international group of researchers, including those from Moffitt Cancer Center in Tampa, Fla., have published a paper in the March 14 issue of the New England Journal of Medicine reviewing the results of a study that a ...
Cancer
Mar 23, 2012 |
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Drug makes leukemia more vulnerable to chemo
(Medical Xpress) -- Doctors at Washington University School of Medicine in St. Louis have shown that a new drug makes chemotherapy more effective in treating acute myeloid leukemia, a cancer of the white blood cells. Instead ...
Cancer
Mar 20, 2012 |
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Study finds genes improving survival with higher chemo doses in leukemia
New research published in the March 15 issue of the New England Journal of Medicine identifies gene mutations associated with improved overall survival with higher doses of chemotherapy for patients with acute myeloid leukem ...
Cancer
Mar 14, 2012 |
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Genetic profiling helps doctors more accurately predict prognosis, guide treatment decisions for leukemia patients
Researchers have identified a set of genetic abnormalities in patients with acute myelogenous leukemia (AML) that doctors can use to more accurately predict patients' prognoses and select treatments that are most likely to ...
Cancer
Mar 14, 2012 |
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Study reports steady increases in long-term survival among children with acute lymphoblastic leukemia
A study by the Children's Oncology Group (COG) reported that five-year survival for acute lymphoblastic leukemia (ALL, the most common type of pediatric cancer) among children treated through COG clinical trials increased ...
Cancer
Mar 12, 2012 |
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Tranylcypromine antidepressant shows promise as cancer treatment
A retinoid called all-trans retinoic acid (ATRA), which is a vitamin A-derivative, is already used successfully to treat a rare sub-type of acute myeloid leukemia (AML), however this drug has not been effective for the more ...
Cancer
Mar 11, 2012 |
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Researchers develop first 'theranostic' treatment for acute lymphoblastic leukemia (ALL)
A team of researchers at Case Western Reserve University School of Medicine has developed the first "theranostic" agent for the treatment of acute lymphoblastic leukemia (ALL). ALL is the most common type of childhood cancer ...
Cancer
Mar 07, 2012 |
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Unraveling why children with Down syndrome have increased leukemia risk
Children with Down syndrome (DS) have an increased risk of developing leukemia, in particular acute megakaryoblastic leukemia (AMKL) and acute lymphoblastic leukemia (ALL). Through their studies in a mouse model of DS, a ...
Genetics
Feb 22, 2012 |
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Inherited risk factors for childhood leukemia are more common in Hispanic patients
Hispanic children are more likely than those from other racial and ethnic backgrounds to be diagnosed with acute lymphoblastic leukemia (ALL) and are more likely to die of their disease. Work led by St. Jude Children's Research ...
Cancer
Jan 30, 2012 |
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Amgen buys Micromet for anti-leukemia drug
Biotech giant Amgen said Thursday it was buying the German-American cancer research firm Micromet, giving it access to Micromet's promising leukemia therapy.
Other
Jan 26, 2012 |
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Study pinpoints and plugs mechanism of AML cancer cell escape
A study published this week in the journal Leukemia identifies a mechanism that acute myeloid leukemia (AML) cells use to evade chemotherapy – and details how to close this escape route.
Cancer
Jan 18, 2012 |
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New culprit discovered in T-cell acute lymphoblastic leukemia
A new study published in the journal Nature Medicine by NYU Cancer Institute researchers, shows how the cancer causing gene Notch, in combination with a mutated Polycomb Repressive Complex 2 (PRC2) protein complex, work t ...
Cancer
Jan 12, 2012 |
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Chemotherapy may influence leukemia relapse: research
The chemotherapy drugs required to push a common form of adult leukemia into remission may contribute to DNA damage that can lead to a relapse of the disease in some patients, findings of a new study suggest.
Cancer
Jan 11, 2012 |
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20 cancer cases in French women with PIP implants: agency
French health authorities said Friday that 20 cases of cancer had been uncovered in women with allegedly faulty French-made breast implants but insisted there was still no proven link with the disease.
Cancer
Dec 30, 2011 |
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