News tagged with acute myeloid


Study identifies possible new acute leukemia marker, treatment target

A study has identified microRNA-155 as a new independent prognostic marker and treatment target in patients with acute myeloid leukemia that has normal-looking chromosomes under the microscope (that is, cytogenetically normal ...

Cancer created May 13, 2013 | popularity not rated yet | comments 0

Genomics to reshape endometrial cancer treatment

The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women.

Cancer created May 01, 2013 | popularity not rated yet | comments 0 | with audio podcast

Thioridazine kills cancer stem cells in human while avoiding toxic side-effects of conventional cancer treatments

A team of scientists at McMaster University has discovered a drug, thioridazine, successfully kills cancer stem cells in the human while avoiding the toxic side-effects of conventional cancer treatments.

Cancer created May 24, 2012 | popularity 4.7 / 5 (55) | comments 5 | with audio podcast

Researchers discover gene defect that predisposes people to leukemia

A new genetic defect that predisposes people to acute myeloid leukemia and myelodysplasia has been discovered. The mutations were found in the GATA2 gene. Among its several regulatory roles, the gene acts ...

Genetics created Sep 04, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Computer algorithms help find cancer connections

Powerful data-sifting algorithms developed by computer scientists at Brown University are helping to untangle the profoundly complex genetics of cancer. In a study reported today in the New England Journal of Medicine, resear ...

Cancer created May 01, 2013 | popularity not rated yet | comments 0 | with audio podcast

Scientists assemble genetic playbook for acute leukemia

A team of researchers led by Washington University School of Medicine in St. Louis has identified virtually all of the major mutations that drive acute myeloid leukemia (AML), a fast-growing blood cancer ...

Cancer created May 01, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Compound that could prevent acute blood cancer relapse identified

Researchers from the RIKEN Center for Integrative Medical Sciences in Japan report today that they have identified a compound that could be used as a new treatment to prevent relapse in acute myeloid leukemia patients.

Cancer created Apr 17, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New genetic mechanism for controlling blood cell development and blood vessel integrity found

The protein GATA2 is known as a "master regulator" of blood cell development. When a mutation occurs in the gene that makes GATA2, serious blood diseases such as acute myeloid leukemia can result.

Genetics created Sep 10, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers identify new strategy for interfering with potent cancer-causing gene

Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible ...

Cancer created Feb 11, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers use new molecular inhibitors to successfully hit difficult cancer target

Early laboratory tests are the first to successfully use an experimental molecular therapy to block a hard-to-target part of a protein complex linked to several types of invasive cancer.

Cancer created Feb 05, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Tranylcypromine antidepressant shows promise as cancer treatment

A retinoid called all-trans retinoic acid (ATRA), which is a vitamin A-derivative, is already used successfully to treat a rare sub-type of acute myeloid leukemia (AML), however this drug has not been effective for the more ...

Cancer created Mar 11, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

FLT3 gene mutations play critically important role in acute myeloid leukemia

The key to treating one of the most common types of human leukemia may lie within mutations in a gene called FLT3, according to new research led by physician-scientists at the University of California, San Francisco (UCSF) ...

Cancer created Apr 15, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Hundreds of random mutations in leukemia linked to aging, not cancer

Hundreds of mutations exist in leukemia cells at the time of diagnosis, but nearly all occur randomly as a part of normal aging and are not related to cancer, new research shows.

Genetics created Jul 19, 2012 | popularity 5 / 5 (5) | comments 3 | with audio podcast

Scientists link 'oncometabolite' to onset of acute myeloid leukemia

A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme ...

Cancer created Jul 04, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Chemotherapy may influence leukemia relapse: research

The chemotherapy drugs required to push a common form of adult leukemia into remission may contribute to DNA damage that can lead to a relapse of the disease in some patients, findings of a new study suggest.

Cancer created Jan 11, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast