News tagged with acute myeloid
Thioridazine kills cancer stem cells in human while avoiding toxic side-effects of conventional cancer treatments
A team of scientists at McMaster University has discovered a drug, thioridazine, successfully kills cancer stem cells in the human while avoiding the toxic side-effects of conventional cancer treatments.
Cancer May 24, 2012 | 4.7 / 5 (55) | 5 |
Hundreds of mutations exist in leukemia cells at the time of diagnosis, but nearly all occur randomly as a part of normal aging and are not related to cancer, new research shows.
Genetics Jul 19, 2012 | 5 / 5 (5) | 3 |
A new genetic defect that predisposes people to acute myeloid leukemia and myelodysplasia has been discovered. The mutations were found in the GATA2 gene. Among its several regulatory roles, the gene acts ...
Genetics Sep 04, 2011 | 5 / 5 (4) | 0 |
One kind of leukemia sometimes masquerades as another, according to a study published online this week in the Journal of Experimental Medicine.
Cancer Dec 12, 2011 | 5 / 5 (4) | 0
Scientists at Virginia Commonwealth University Massey Cancer Center may be one step closer to developing a new therapy for acute myeloid leukemia (AML) after discovering that the targeted agents obatoclax and sorafenib kill ...
Cancer May 22, 2012 | 5 / 5 (3) | 0
A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme ...
Cancer Jul 04, 2012 | 5 / 5 (3) | 0 |
(Medical Xpress) -- Parents, siblings and children of patients with the most common form of acute leukemia do not run a higher risk of developing the disease as was once believed, according to a new study from the Swedish ...
Cancer Dec 15, 2011 | 5 / 5 (2) | 0 |
The chemotherapy drugs required to push a common form of adult leukemia into remission may contribute to DNA damage that can lead to a relapse of the disease in some patients, findings of a new study suggest.
Cancer Jan 11, 2012 | 5 / 5 (2) | 0 |
A study published this week in the journal Leukemia identifies a mechanism that acute myeloid leukemia (AML) cells use to evade chemotherapy and details how to close this escape route.
Cancer Jan 18, 2012 | 5 / 5 (2) | 0
Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible ...
Cancer Feb 11, 2013 | 5 / 5 (2) | 0 |
Researchers from the RIKEN Center for Integrative Medical Sciences in Japan report today that they have identified a compound that could be used as a new treatment to prevent relapse in acute myeloid leukemia patients.
Cancer Apr 17, 2013 | 5 / 5 (2) | 0 |
Scientists at Cold Spring Harbor Laboratory (CSHL) and five other institutions have used an unconventional approach to cancer drug discovery to identify a new potential treatment for acute myeloid leukemia (AML). As reported ...
Cancer Aug 03, 2011 | 3.5 / 5 (2) | 0 |
Human stem cells aren't immune to the aging process, according to scientists at the Stanford University School of Medicine. The researchers studied hematopoietic stem cells, which create the cells that comprise the blood ...
Medical research Nov 28, 2011 | 3 / 5 (2) | 0 |
Cancer scientists have long debated whether all cells within a tumour are equal or whether some cancer cells are more potent - a question that has been highly investigated in experimental models in the last decade. Research ...
Cancer Aug 28, 2011 | 5 / 5 (1) | 0 |
Cancer researchers at Cold Spring Harbor Laboratory (CSHL) have carried out the first comprehensive study of the changes seen in the DNA of a patient with mast cell leukemia (MCL), an extremely aggressive subtype of acute ...
Cancer Dec 16, 2011 | 5 / 5 (1) | 0 |