News tagged with acute myeloid
Genomics to reshape endometrial cancer treatment
The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women.
Cancer
May 01, 2013 |
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Scientists link 'oncometabolite' to onset of acute myeloid leukemia
A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme ...
Cancer
Jul 04, 2012 |
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New breast cancer genetic alterations discovered
Breast cancer is not a single disease, but a collection of diseases with dozens of different mutations that crop up with varying frequency across different breast cancer subtypes. Deeper exploration of the genetic changes ...
Cancer
Jun 20, 2012 |
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FLT3 gene mutations play critically important role in acute myeloid leukemia
The key to treating one of the most common types of human leukemia may lie within mutations in a gene called FLT3, according to new research led by physician-scientists at the University of California, San Francisco (UCSF) ...
Cancer
Apr 15, 2012 |
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Tranylcypromine antidepressant shows promise as cancer treatment
A retinoid called all-trans retinoic acid (ATRA), which is a vitamin A-derivative, is already used successfully to treat a rare sub-type of acute myeloid leukemia (AML), however this drug has not been effective for the more ...
Cancer
Mar 11, 2012 |
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Chemotherapy may influence leukemia relapse: research
The chemotherapy drugs required to push a common form of adult leukemia into remission may contribute to DNA damage that can lead to a relapse of the disease in some patients, findings of a new study suggest.
Cancer
Jan 11, 2012 |
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Aging stem cells may explain higher prevalence of leukemia, infections among elderly
Human stem cells aren't immune to the aging process, according to scientists at the Stanford University School of Medicine. The researchers studied hematopoietic stem cells, which create the cells that comprise the blood ...
Medical research
Nov 28, 2011 |
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Researchers discover gene defect that predisposes people to leukemia
A new genetic defect that predisposes people to acute myeloid leukemia and myelodysplasia has been discovered. The mutations were found in the GATA2 gene. Among its several regulatory roles, the gene acts ...
Genetics
Sep 04, 2011 |
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Scientists assemble genetic playbook for acute leukemia
A team of researchers led by Washington University School of Medicine in St. Louis has identified virtually all of the major mutations that drive acute myeloid leukemia (AML), a fast-growing blood cancer ...
Cancer
May 01, 2013 |
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Computer algorithms help find cancer connections
Powerful data-sifting algorithms developed by computer scientists at Brown University are helping to untangle the profoundly complex genetics of cancer. In a study reported today in the New England Journal of Medicine, resear ...
Cancer
May 01, 2013 |
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Compound that could prevent acute blood cancer relapse identified
Researchers from the RIKEN Center for Integrative Medical Sciences in Japan report today that they have identified a compound that could be used as a new treatment to prevent relapse in acute myeloid leukemia patients.
Cancer
Apr 17, 2013 |
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Study demonstrates effects of mutant IDH1 and IDH2 inhibitors in primary tumor models
Agios Pharmaceuticals announced today the publication of two articles in the journal Science by Agios scientists and their collaborators demonstrating the effects of the company's small molecule isocitrate dehydrogenase 1 and ...
Cancer
Apr 04, 2013 |
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Researchers identify genetic variation behind acute myeloid leukemia treatment success
Researchers from the College of Pharmacy and Medical School working within the Masonic Cancer Center, University of Minnesota, have partnered to identify genetic variations that may help signal which acute myeloid leukemia ...
Cancer
Feb 26, 2013 |
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Researchers identify new strategy for interfering with potent cancer-causing gene
Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible ...
Cancer
Feb 11, 2013 |
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Researchers use new molecular inhibitors to successfully hit difficult cancer target
Early laboratory tests are the first to successfully use an experimental molecular therapy to block a hard-to-target part of a protein complex linked to several types of invasive cancer.
Cancer
Feb 05, 2013 |
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