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Scientists can now block heroin, morphine addiction; clinical trials possible within 18 months

In a major breakthrough, an international team of scientists has proven that addiction to morphine and heroin can be blocked, while at the same time increasing pain relief.

Neuroscience created Aug 14, 2012 | popularity 4.9 / 5 (30) | comments 8 | with audio podcast

Dopamine not about pleasure (anymore)

(Medical Xpress)—To John Salamone, professor of psychology and longtime researcher of the brain chemical dopamine, scientific research can be very slow-moving.

Neuroscience created Dec 03, 2012 | popularity 4.9 / 5 (14) | comments 1 | with audio podcast

Resetting addicted brain: Laser light zaps away cocaine addiction

By stimulating one part of the brain with laser light, researchers at the National Institutes of Health (NIH) and the Ernest Gallo Clinic and Research Center at UC San Francisco (UCSF) have shown that they ...

Neuroscience created Apr 03, 2013 | popularity 5 / 5 (11) | comments 7 | with audio podcast

Herbal drug reduces the effects of alcohol

(Medical Xpress) -- Alcohol consumption can lead to those dreaded hangovers and even alcohol dependence. However, a new study published in the Journal of Neuroscience has found a natural ingredient in the ...

Neuroscience created Jan 05, 2012 | popularity 4.9 / 5 (11) | comments 9 | with audio podcast report

A classic instinct -- salt appetite -- is linked to drug addiction

A team of Duke University Medical Center and Australian scientists has found that addictive drugs may have hijacked the same nerve cells and connections in the brain that serve a powerful, ancient instinct: ...

Medical research created Jul 11, 2011 | popularity 4.8 / 5 (11) | comments 4 | with audio podcast

Researchers develop novel anti-body vaccine that blocks addictive nicotine chemicals from reaching the brain

Researchers at Weill Cornell Medical College have developed and successfully tested in mice an innovative vaccine to treat nicotine addiction.

Medical research created Jun 27, 2012 | popularity 5 / 5 (7) | comments 7 | with audio podcast

Enzyme might be target for treating smoking, alcoholism at same time

An enzyme that appears to play a role in controlling the brain's response to nicotine and alcohol in mice might be a promising target for a drug that simultaneously would treat nicotine addiction and alcohol abuse in people, ...

Medical research created Sep 12, 2011 | popularity 4.7 / 5 (6) | comments 0 | with audio podcast

New kind of memory trick may help drug addicts recover

(Medical Xpress) -- Traditionally, treatment for drug addicts has centered around so-called extinction procedures designed to disassociate memories tied with taking drugs to help reduce the cravings that so often result in ...

Addiction created Apr 13, 2012 | popularity 4.7 / 5 (6) | comments 0 | with audio podcast report

New hope for addicts

It doesn't take a rocket scientist to quickly grasp what a University of Mississippi professor's research could mean to the millions of people addicted to hardcore narcotics such as heroin, cocaine, methamphetamine and morphine.

Addiction created Jan 28, 2013 | popularity 5 / 5 (5) | comments 1

Researchers argue 'addiction' a poor way to understand the normal use of drugs

A new review from UK and German researchers claims that the vast majority of people who routinely use drugs are using them to achieve their goals and cope better with the stresses of modern life.

Other created Apr 12, 2011 | popularity 5 / 5 (4) | comments 8

Internet addiction disorder characterized by abnormal white matter integrity

Internet addiction disorder may be associated with abnormal white matter structure in the brain, as reported in the Jan. 11 issue of the online journal PLoS ONE. These structural features may be linked to behavioral impair ...

Psychology & Psychiatry created Jan 11, 2012 | popularity 3.3 / 5 (6) | comments 0

Study shows how neurons interact, could lead to new treatment for addiction

Harvard scientists have developed the fullest picture yet of how neurons in the brain interact to reinforce behaviors ranging from learning to drug use, a finding that might open the door to possible breakthroughs in the ...

Neuroscience created Jan 18, 2012 | popularity 5 / 5 (4) | comments 1 | with audio podcast

People love talking about themselves, brain scans show

(HealthDay) -- Got something to report about yourself? An opinion, perhaps, or a status update? Nobody may care except you, but new brain research suggests you can make yourself feel good simply by sharing.

Psychology & Psychiatry created May 07, 2012 | popularity 5 / 5 (4) | comments 5 | with audio podcast

The brain on drugs: Defining the neural anatomy and physiology of morphine on dopamine neurons

(Medical Xpress) -- Morphine's analgesic properties are as potent as its addictive potential are problematic. The neural pathway for that addiction is typically associated with dopamine (DA) neurons of the ...

Neuroscience created Oct 04, 2011 | popularity 4.8 / 5 (4) | comments 1 | with audio podcast feature

Frequent gamers have brain differences, study finds

Fourteen-year-olds who were frequent video gamers had more gray matter in the rewards center of the brain than peers who didn't play video games as much - suggesting that gaming may be correlated to changes in the brain, ...

Psychology & Psychiatry created Nov 15, 2011 | popularity 4.8 / 5 (4) | comments 4

Addiction

The term "addiction" is used in many contexts to describe an obsession, compulsion, or excessive psychological dependence, such as: drug addiction (e.g. alcoholism), video game addiction, crime, money, work addiction, compulsive overeating, problem gambling, computer addiction, nicotine addiction, pornography addiction, etc.

In medical terminology, an addiction is a chronic neurobiologic disorder that has genetic, psychosocial, and environmental dimensions and is characterized by one of the following: the continued use of a substance despite its detrimental effects, impaired control over the use of a drug (compulsive behavior), and preocupation with a drug's use for non-therapeutic purposes (i.e. craving the drug). Addiction is often accompanied the presence of deviant behaviors (for instance stealing money and forging prescriptions) that are used to obtain a drug.

Tolerance to a drug and physical dependence are not defining characteristics of addiction, although they typically accompany addiction to certain drugs. Tolerance is a pharmacologic phenomenon where the dose of a medication needs to be continually increase in order to maintain its desired effects. For instance, individuals with severe chronic pain taking opiate medications (like morphine) will need to continually increase the dose in order to maintain the drug's analgesic (pain-relieving) effects. Physical dependence is also a pharmacologic property and means that if a certain drug is abruptly discontinued, an individual will experience certain characteristic withdrawal signs and symptoms. Many drugs used for therapeutic purposes produce withdrawal symptoms when abruptly stopped, for instance oral steroids, certain antidepressants, benzodiazepines, and opiates.

However, common usage of the term addiction has spread to include psychological dependence. In this context, the term is used in drug addiction and substance abuse problems, but also refers to behaviors that are not generally recognized by the medical community as problems of addiction, such as compulsive overeating.

The term addiction is also sometimes applied to compulsions that are not substance-related, such as problem gambling and computer addiction. In these kinds of common usages, the term addiction is used to describe a recurring compulsion by an individual to engage in some specific activity, despite harmful consequences, as deemed by the user himself to his or her individual health, mental state or social life.

For more information about Addiction, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: brain , alcohol , nicotine