Oncology & Cancer
Chemotherapy alters immune cell landscape in pancreatic cancer
Chemotherapy affects the ability of a patient's immune system to attack pancreatic tumors, a new study shows.
Mar 1, 2023
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News tagged with adenocarcinoma
Medical research
Recruitment mechanism discovered for cancer-associated fibroblasts in common lung cancer
A team of experts from the University of Barcelona, the University of Zaragoza and Hospital Clínic de Barcelona has found a mechanism of recruitment for tumor-associated cells (cancer-associated fibroblasts or CAFs), which ...
Jan 31, 2023
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Oncology & Cancer
KRAS mutation shown to promote tumor evasion of innate immune surveillance in lung cancer
KRAS is one of the most frequently activated oncogenes in human cancers. While the role of KRAS mutation in tumorigenesis and tumor maintenance has been extensively studied, the relationship between KRAS and the tumor immune ...
Jan 20, 2023
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Medical research
Discovery of cancer-associated fibroblast origin gives new direction for pancreatic cancer research
A type of cell that plays a key role in pancreatic cancer can trace its origin back to a structure that forms during embryonic development, new research at MUSC Hollings Cancer Center shows. This new data, published recently ...
Jan 20, 2023
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Medical research
Lethal cancer cells buddy up to survive
Tumor cells in the most common pancreatic cancer share nutrients to live and grow. A new discovery by University of California, Irvine biologists and collaborators during a four-year investigation could help lead to better ...
Nov 22, 2022
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Medical research
Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas
A widely-circulated clinical trial published earlier this year in the New England Journal of Medicine (NEJM) described a new treatment that eradicated cancer in all 12 of its patients with locally advanced mismatch repair ...
Nov 2, 2022
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Oncology & Cancer
Genetic variation explains racial disparity in esophageal cancer cases
Esophageal adenocarcinoma (EAC) is a type of cancer affecting the mucus-secreting glands of the lower esophagus—the tube connecting the throat to the stomach. It is the most common form of esophageal cancer and often preceded ...
Sep 22, 2022
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Medical research
The structure of protein RAF1 revealed: A key step in the development of new drugs against lung cancer
One of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes—genes that cause cancer when mutated—are responsible for a quarter of all human cancers, including the three tumor ...
Sep 1, 2022
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Oncology & Cancer
Mapping the 'energy fingerprints' of lung cancer leads to fundamental treatment rethink
Melbourne researchers have discovered that cancer and immune cells rely on the same energy sources from our body to thrive, which could trigger a fundamental rethink of treatment options for some lung cancer patients.
Jun 30, 2022
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Oncology & Cancer
Discovery of a molecular switch in pancreatic cancer cells that triggers metastatic disease
More than 62,000 people in the United States will be diagnosed with pancreatic cancer by the end of this year, with the vast majority having a deadly and aggressive subtype known as pancreatic ductal adenocarcinoma (PDA). ...
Jun 27, 2022
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