Genetics

Uncovering cellular mechanisms of genetic skin diseases

Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal of Clinical Investigation.

Medical research

Synthetic tissue model with blood vessels developed

Using lab-created tissue to heal or replace damaged organs is one of the great visions for the future of medicine. Synthetic materials could be suitable as scaffolding for tissue because, unlike natural tissues, they remain ...

Medical research

Shootin1a—the missing link underlying learning and memory

In neurons, changes in the size of dendritic spines—small cellular protrusions involved in synaptic transmission—are thought to be a key mechanism underlying learning and memory. However, the specific way in which these ...

Immunology

New antibody rationally designed for better tumor inhibition

Recently, Prof. Xie Can from the High Magnetic Field Laboratory of the Hefei Institutes of Physical Science (HFIPS), in a collaboration with Prof. Yan Xiyun's lab from the Institute of Biophysics, reported the structural ...

Neuroscience

Astrocytes identified as master 'conductors' of the brain

In the orchestra of the brain, the firing of each neuron is controlled by two notes—excitatory and inhibitory—that come from two distinct forms of a cellular structure called synapses. Synapses are essentially the connections ...

Immunology

Fever alters immune cells so they can better reach infections

Fever is known to help power up our immune cells, and scientists in Shanghai have new evidence explaining how. They found in mice that fever alters surface proteins on immune cells like lymphocytes to make them better able ...

Neuroscience

Diffusible guidance molecule that divides the brain

Boundaries between different regions of the brain are essential for the brain to function. Research to date has shown that molecular machinery located at the cell membrane, such as cell adhesion molecules, are responsible ...

Parkinson's & Movement disorders

Biomarkers link fatigue in cancer, Parkinson's

Biological markers responsible for extreme exhaustion in patients with cancer have now been linked to fatigue in those with Parkinson's disease, according to new research from Rice University.

Neuroscience

Neuronal 'barcodes' shape complex networks in the brain

The brain is an enormously complex organ. Understanding how billions of brain cells make precise connections is a major challenge for neuroscientists. Professor Joris de Wit and his team (VIB-KU Leuven) have unraveled a molecular ...

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