The MYCN oncoprotein (proteins related to the growth of cancer cells) plays a key role in starting, advancing and making it difficult to treat various human cancers. When MYCN is overactive, especially in high-risk neuroblastoma ...
Mar 15, 2024
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Researchers have newly identified a universal, essential biomarker for the childhood cancer neuroblastoma—and a potential new target for treatment.
Feb 28, 2024
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Injecting neuroblastoma tumors with Zika virus shrank or eliminated those tumors in studies with mice, suggesting that the virus could someday serve as an effective cancer therapy, according to a study led by Nemours Children's ...
Jan 9, 2024
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Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.
Mar 28, 2023
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Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN ...
Aug 17, 2022
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Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands. This discovery explains how impaired metabolism due to mutations in a key ...
Aug 16, 2022
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Dying of a broken heart was just a figure of speech until 2002 when Dr. Hikaru Sato and colleagues at Hiroshima City Hospital described it in a study. Sato named the condition takotsubo cardiomyopathy. It was quickly dubbed ...
Jul 14, 2022
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Advanced forms of hormone therapy are very effective at keeping prostate cancer in check, but they also can double a man's risk of falling into depression, researchers have found.
Jan 18, 2022
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Recent advances in immunotherapy have allowed doctors at the University of Colorado Cancer Center to more effectively treat melanomas that spread to other parts of the body. Immunotherapy drugs such as checkpoint inhibitors, ...
Sep 23, 2021
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An international study, involving Newcastle University, has for the first time found a genetic marker in tumors from patients with high-risk neuroblastoma.
Jun 21, 2021
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