Scientists identify new target for Parkinson's therapies
A master control region of a protein linked to Parkinson's disease has been identified for the first time.
Mar 9, 2020
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A master control region of a protein linked to Parkinson's disease has been identified for the first time.
Mar 9, 2020
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Utrecht scientists have uncovered how aggregates alter the behavior of Tau protein, known to play a role in Alzheimer's disease. On a molecular level, the researchers have revealed why certain proteins tend to bind to Tau ...
Jan 31, 2020
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West Nile virus (WNV) inhibits autophagy to induce the aggregation of proteins in infected cells, triggering cell death and brain inflammation (encephalitis), according to Hokkaido University researchers. They also discovered ...
Jan 23, 2020
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Neurodegenerative diseases such as Alzheimer's and Parkinson's can be devastating to patients and their families. These diseases are difficult to diagnose before symptoms show, meaning it's often already too late to reverse ...
Dec 17, 2019
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Protein aggregates have been observed in the nerve tissue of patients with Parkinson's disease which consist of individual components (monomers) of the protein α-synuclein which assemble into what are referred to as amyloid ...
Sep 3, 2019
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Protein aggregation—in which misfolded proteins clump together to form large fibrils—has been implicated in many diseases including Alzheimer's, Parkinson's, and type II diabetes. While the exact role these fibrils play ...
Aug 16, 2019
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Tree-like branching structures are everywhere in the human body, from the bronchial system in the lungs to the spidering capillaries that supply blood to the extremities. Researchers have long worked to understand the cellular ...
Aug 12, 2019
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Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier—the normally tight border that ...
Aug 12, 2019
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The true cause of Parkinson's disease is still a mystery to researchers, although they do know that in many patients, a protein called alpha-synuclein (aSyn) tends to aggregate in brain cells. But a different protein could ...
Jun 11, 2019
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ETH researchers have discovered a new mechanism that brain cells use to protect themselves from protein aggregates. Such aggregates play a key role in Parkinson's and other neurodegenerative diseases. This new finding might ...
Jun 6, 2019
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