Tumors evolve rapidly in a childhood cancer, leaving fewer obvious tumor targets
An extensive genomic study of the childhood cancer neuroblastoma reinforces the challenges in treating the most aggressive forms of this disease. Contrary to expectations, the scientists found relatively few recurrent gene ...
Genetics
Jan 20, 2013 |
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Body's ibuprofen, SPARC, reduces inflammation and thus bladder cancer development and metastasis
Cancer researchers are increasingly aware that in addition to genetic mutations in a cancer itself, characteristics of the surrounding tissue can promote or suppress tumor growth. One of these important tissue characteristics ...
Cancer
Jan 16, 2013 |
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Change in PSA levels over time can help predict aggressive prostate cancer
Measurements taken over time of prostate specific antigen, the most commonly used screening test for prostate cancer in men, improve the accuracy of aggressive prostate cancer detection when compared to a single measurement ...
Cancer
Jan 15, 2013 |
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Researchers discover novel role of the NEDD9 gene in early stages of breast cancer
Breast cancer is the second leading cause of cancer deaths among women in the United States. Many of these deaths occur when there is an initial diagnosis of invasive or metastatic disease. A protein called NEDD9—which ...
Cancer
Jan 14, 2013 |
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ASH international clinical collaboration replicates high cure rate of APL in developing countries
Data published online today in Blood, the Journal of the American Society of Hematology (ASH) describe the work of an ASH international clinical network collaborative focused on modernizing treatment protocols for patien ...
Cancer
Jan 14, 2013 |
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Smoking intensity and cancer markers predict seriousness of bladder cancer
it also affects its course, in that people who smoke more have greater likelihood of developing more aggressive and deadly disease. That is one of the conclusions of a new study published early online in Cancer, a peer-r ...
Cancer
Jan 14, 2013 |
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Sickle cells show potential to attack aggressive cancer tumors
By harnessing the very qualities that make sickle cell disease a lethal blood disorder, a research team led by Duke Medicine and Jenomic, a private cancer research company in Carmel, Calif., has developed ...
Cancer
Jan 09, 2013 |
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Two-drug combination may slow deadly thyroid cancer
A combination of the drugs pazopanib and paclitaxel shows promise in slowing anaplastic thyroid cancer (ATC), according to a Mayo Clinic-led study published in the journal Science Translational Medicine. The two drugs togeth ...
Cancer
Jan 08, 2013 |
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Preventing prostate cancer through androgen deprivation may have harmful effects
Mice deficient in PTEN in the prostate developed stable precancers. Androgen deprivation promoted progression to invasive prostate cancer. Patients with PTEN-deficient prostate precancers may not benefit from androgen deprivation ...
Cancer
Dec 20, 2012 |
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Patients with family history of colorectal cancer may be at risk for aggressive form of the disease
BOSTON—When people with a family history of colorectal cancer develop the disease, their tumors often carry a molecular sign that the cancer could be life-threatening and may require aggressive treatment, Dana-Farber Cancer ...
Cancer
Dec 12, 2012 |
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Drug combination acts against aggressive chronic lymphocytic leukemia
A two-prong approach combining ibrutinib and rituximab (Rituxin®) to treat aggressive chronic lymphocytic leukemia (CLL) produced profound responses with minor side effects in a Phase 2 clinical trial at the University of ...
Cancer
Dec 10, 2012 |
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Researchers develop novel 3-D culture system for inflammatory breast cancer
Inflammatory breast cancer (IBC) is a very rare and aggressive disease that progresses rapidly and is associated with a very low survival rate. To understand how this type of cancer spreads, it's crucial to characterize the ...
Cancer
Dec 09, 2012 |
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COUP-TFII sparks prostate cancer progression
Prostate cancer presents a dilemma for patients and the physicians who treat them. Which cancers are essentially indolent and present no risk and which are life threatening? Which can be watched and which need aggressive ...
Cancer
Nov 28, 2012 |
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Boosting immune responses against leukaemia
(Medical Xpress)—In the first of its kind, a translational study undertaken at the Malaghan Institute of Medical Research has revealed that boosting the activity of a rare type of immune cell could be an ...
Cancer
Nov 21, 2012 |
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Compound in grapes, red wine could be key to fighting prostate cancer
Resveratrol, a compound found commonly in grape skins and red wine, has been shown to have several beneficial effects on human health, including cardiovascular health and stroke prevention. Now, a University ...
Cancer
Nov 10, 2012 |
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