Immunology

Obesity alters airway muscle function, increases asthma risk

New research suggests that obesity changes how airway muscles function, increasing the risk of developing asthma. The study is published ahead of print in the American Journal of Physiology—Lung Cellular and Molecular Physiology.

Inflammatory disorders

Experimental drug targets nucleus of allergen-sensitized cells

Transcription factors, the tiny proteins that switch genes on or off in the nucleus of cells, are considered unreachable molecular targets for drugs attempting to treat medical conditions. Overcoming this challenge, researchers ...

Diseases, Conditions, Syndromes

Study reveals surprises concerning COPD and smoking

A new study challenges the widely accepted but oversimplified description of airway inflammation in smokers and patients with chronic obstructive pulmonary disease (COPD).

Inflammatory disorders

Why is asthma worse in black patients?

African Americans may be less responsive to asthma treatment and more likely to die from the condition, in part, because they have a unique type of airway inflammation, according to a study led by researchers at the University ...

Immunology

Test used to diagnose asthma may not be accurate

A new study urges caution in the use of the mannitol challenge test for asthma in non-clinical settings. The test is considered widely applicable to detect asthma, but its accuracy outside of patients referred for specialized ...

Immunology

Resveratrol can help to reduce inflammation, study finds

A component of red wine and grapes can help control inflammation induced by a bacterial pathogen that is linked to upper respiratory tract inflammatory diseases such as asthma, chronic obstructive pulmonary diseases (COPD) ...

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