Diabetes

FDA approves two new medications for diabetes

(HealthDay)—Two new diabetes treatments, Tresiba (insulin degludec injection) and Ryzodeg (insulin degludec/insulin aspart injection), have been approved by the U.S. Food and Drug Administration.

Diseases, Conditions, Syndromes

Serious adverse effects from COVID-19 vaccines reported rarely

(HealthDay)—Patient-reported data indicate certain factors, such as vaccine brand (mRNA-1273) and younger age, are associated with an increased risk for adverse effects following COVID-19 vaccination, but serious adverse ...

Immunology

Alpha-gal found to be both a medication and red meat allergy

Alpha-gal allergy has commonly been referred to as "the red meat" allergy, but doctors at the Vanderbilt Asthma, Sinus and Allergy Program (ASAP) helped uncover that not only red meat, but some medications, can contain alpha-gal.

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Allergy

Allergy is a disorder of the immune system often also referred to as atopy. Allergic reactions occur to normally harmless environmental substances known as allergens; these reactions are acquired, predictable, and rapid. Strictly, allergy is one of four forms of hypersensitivity and is called type I (or immediate) hypersensitivity. It is characterized by excessive activation of certain white blood cells called mast cells and basophils by a type of antibody known as IgE, resulting in an extreme inflammatory response. Common allergic reactions include eczema, hives, hay fever, asthma, food allergies, and reactions to the venom of stinging insects such as wasps and bees.

Mild allergies like hay fever are highly prevalent in the human population and cause symptoms such as allergic conjunctivitis, itchiness, and runny nose. Allergies can play a major role in conditions such as asthma. In some people, severe allergies to environmental or dietary allergens or to medication may result in life-threatening anaphylactic reactions and potentially death.

A variety of tests now exist to diagnose allergic conditions; these include testing the skin for responses to known allergens or analyzing the blood for the presence and levels of allergen-specific IgE. Treatments for allergies include allergen avoidance, use of anti-histamines, steroids or other oral medications, immunotherapy to desensitize the response to allergen, and targeted therapy.

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