News tagged with american journal of pathology


New discovery expected to significantly change biomedical research

In a major step that could revolutionize biomedical research, scientists have discovered a way to keep normal cells as well as tumor cells taken from an individual cancer patient alive in the laboratory — ...

Cancer created Dec 19, 2011 | popularity 5 / 5 (7) | comments 6 | with audio podcast

Protein found to regulate spread of pancreatic cancer cells

Researchers at Queen Mary, University of London have identified a new protein that makes pancreatic cancer cells less 'sticky' and therefore less able to attach to and invade other tissue.

Cancer created Mar 26, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Adult stem cells change their epigenome to generate new organs

A study developed by researchers at the IDIBELL, led by Manel Esteller, has identified epigenetic changes that occur in adult stem cells to generate different tissues of the human body.

Medical research created Oct 02, 2012 | popularity 5 / 5 (2) | comments 1

New study first to image concussion-related abnormal brain proteins in retired NFL players

Sports-related concussions and mild traumatic brain injuries have grabbed headlines in recent months, as the long-term damage they can cause becomes increasingly evident among both current and former athletes. ...

Neuroscience created Jan 22, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers report new understanding of role of telomeres in tumor growth

The first report of the presence of alternative lengthening of telomeres (ALT) in cancers arising from the bladder, cervix, endometrium, esophagus, gallbladder, liver, and lung was published today in The American Journal of ...

Cancer created Sep 01, 2011 | popularity 5 / 5 (1) | comments 0

Bone marrow cells migrate to tumors and can slow their growth

Bone marrow-derived cells (BMDCs) participate in the growth and spread of tumors of the breast, brain, lung, and stomach. To examine the role of BMDCs, researchers developed a mouse model that could be used to track the migration ...

Cancer created Oct 07, 2011 | popularity 5 / 5 (1) | comments 0

Researchers find link between pulmonary inflammation, diesel exhaust, house dust

A study conducted by researchers at Boston University School of Medicine (BUSM) has found that diesel exhaust particulates (DEP) and house dust extract (HDE) causes pulmonary inflammation that aggravates asthma. The study ...

Health created Dec 14, 2011 | popularity 5 / 5 (1) | comments 0

Insulin therapy may help repair atherosclerotic lesions in diabetic patients

New research reveals that insulin applied in therapeutic doses selectively stimulates the formation of new elastic fibers in cultures of human aortic smooth muscle cells. These results advance the understanding of the molecular ...

Diseases, Conditions, Syndromes created Jan 09, 2012 | popularity 5 / 5 (1) | comments 0

New software opens the door to wider use of 3-D imaging in the study of disease

Researchers have developed a novel, easy-to-use system for three-dimensional (3D) reconstruction and examination of tissues at microscopic resolution, with the potential to significantly enhance the study of normal and disease ...

Medical research created Apr 16, 2012 | popularity 5 / 5 (1) | comments 0

'Mad cow disease' in cattle can spread widely in ANS before detectable in CNS

Bovine spongiform encephalopathy (BSE, or "mad cow disease") is a fatal disease in cattle that causes portions of the brain to turn sponge-like. This transmissible disease is caused by the propagation of a misfolded form ...

Diseases, Conditions, Syndromes created Jul 09, 2012 | popularity 5 / 5 (1) | comments 0

Butter flavoring in microwave popcorn, thought safe for food industry workers, is respiratory hazard

The ingredient 2,3-pentanedione (PD), used to impart the flavor and aroma of butter in microwave popcorn, is a respiratory hazard that can also alter gene expression in the brain of rats. Manufacturers started using PD when ...

Health created Aug 13, 2012 | popularity 5 / 5 (1) | comments 0

Activation of cortical type 2 cannabinoid receptors ameliorates ischemic brain injury

A new study published in the March issue of The American Journal of Pathology suggests that cortical type 2 cannabinoid (CB2) receptors might serve as potential therapeutic targets for cerebral ischemia.

Medical research created Feb 21, 2013 | popularity 5 / 5 (1) | comments 0

Ranibizumab may prevent retinal detachment side effect

Proliferative vitreoretinopathy (PVR), or the formation of scar tissue in the eye, is a serious, sight-threatening complication in people recovering from surgical repair of retinal detachment. PVR is difficult to predict, ...

Ophthalmology created Apr 09, 2013 | popularity 5 / 5 (1) | comments 0

New hope for spinal cord injury patients

A new antibody could reverse the damage caused by trauma to the central nervous system, according to new research.

Diseases, Conditions, Syndromes created Aug 29, 2012 | popularity 3 / 5 (1) | comments 0

Tamoxifen ameliorates symptoms of Duchenne muscular dystrophy

A new study has found that tamoxifen, a well-known breast cancer drug, can counteract some pathologic features in a mouse model of Duchenne muscular dystrophy (DMD). At present, no treatment is known to produce ...

Diseases, Conditions, Syndromes created Jan 15, 2013 | popularity 3 / 5 (1) | comments 0 | with audio podcast