Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease. The study, "Rare ...
Apr 10, 2024
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In people with Alzheimer's disease (AD), the epigenetic regulator HDAC6 (histone deacetylase 6), which controls many biological processes, is significantly overexpressed in the brain.
Nov 27, 2023
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Three men who had heart failure caused by the build-up of sticky, toxic proteins are now free of symptoms after their condition spontaneously reversed in an unprecedented case described by a team at UCL (University College ...
Jun 7, 2023
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Columbia researchers have found a link between a common back ailment and a type of heart failure, suggesting that screening patients with lumbar spinal stenosis could identify those at risk of the heart disease and prevent ...
Aug 31, 2022
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On the surface, Parkinson's disease—a neurodegenerative disorder—and melanoma—a type of skin cancer—do not appear to have much in common. However, for nearly 50 years, doctors have recognized that Parkinson's disease ...
Apr 7, 2021
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A hypothesis which has been the standard way of explaining how the body develops Alzheimer's Disease for almost 30 years is flawed, according to a University of Manchester biologist.
Oct 16, 2018
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A team of researchers from the Cleveland Clinic Lerner Research Institute have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer's ...
Feb 14, 2018
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Researchers at Boston Children's Hospital show how brain connections, or synapses, are lost early in Alzheimer's disease and demonstrate that the process starts—and could potentially be halted—before telltale plaques ...
Mar 31, 2016
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Researchers have used a non-invasive method of observing how the process leading to Parkinson's disease takes place at the nanoscale, and identified the point in the process at which proteins in the brain become toxic, eventually ...
Mar 14, 2016
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A group of villagers on the Pacific island of Guam has offered some key insight into the role that an environmental toxin may play in brain changes that are a hallmark of Alzheimer's disease. And scientists studying that ...
Jan 20, 2016
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